Typical dietary habits and elevated intestinal permeability in people with excess body weight and IBS
https://doi.org/10.31146/1682-8658-ecg-190-6-50-56
Abstract
To optimize non-drug methods of treatment of patients with irritable bowel syndrome (IBS) against the background of obesity to identify the peculiarities of food preferences and permeability of the intestinal wall.
Materials and methods: An anonymous questionnaire survey of 52 IBS patients was carried out using the author’s set of dietary assessment questions “Nutrition Information and Food Behavior” developed at the Department of Hygiene, Human Nutrition of Omsk State Medical University. The study of the level of zonulin in the feces was carried out at the Central Research Laboratory of the Federal State Budgetary Educational Institution of Higher Professional Education Omsk State Medical University of the Ministry of Health of Russia by enzyme immunoassay using the IDK Zonulin ELISA test system (Immundiagnostik, Germany).
Results: The eating habits of IBS patients with BMI ≥25 kg/m2 diff er from those of normal weight patients and can be considered a component of the phenotype of this patient cohort. IBS patients with BMI ≥25 kg/m2 have a higher level of intestinal permeability as assessed by zonulin content in feces.
About the Authors
M. M. Fedorin
Federal State Educational Establishment of Higher Education Omsk State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Maksim M. Fedorin, Resident at the Department of Faculty Therapy and Gastroenterology
12 Lenina street, 644099 Omsk, Russia
O. V. Gaus
Federal State Educational Establishment of Higher Education Omsk State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Olga V. Gaus, Cand. Sci. (Med.), Associate Professor of the Department of Faculty Therapy and Gastroenterology. Scopus Author ID: 56598554900
12 Lenina street, 644099 Omsk, Russia
M. A. Livzan
Federal State Educational Establishment of Higher Education Omsk State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Maria A. Livzan, D. Sci. (Med.), Professor, Rector, Head of the Department of Faculty Therapy and Gastroenterology. Scopus Author ID: 24341682600
12 Lenina street, 644099 Omsk, Russia
S. A. Sukhanova
Federal State Educational Establishment of Higher Education Omsk State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Sofi a A. Sukhanova, 5th year student of the Faculty of Medicine
12 Lenina street, 644099 Omsk, Russia
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For citations:
Fedorin M.M., Gaus O.V., Livzan M.A., Sukhanova S.A. Typical dietary habits and elevated intestinal permeability in people with excess body weight and IBS. Experimental and Clinical Gastroenterology. 2021;1(6):50-56. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-190-6-50-56
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