The effect of fats and their hydrolysis products on the proteolytic activity of pancreatic and gastric juices
https://doi.org/10.31146/1682-8658-ecg-179-7-131-136
Abstract
The effect of various concentrations of fat hydrolysis products on the pancreatic and gastric juices OPA using casein-fat emulsion (casein + tributyrin, casein + sunflower oil) was studied. It is concluded that the hydrolysis products of sunflower oil, contributes to a significant decrease in pancreatic juice OPA, which are less pronounced under the influence of tributyrin hydrolysis products.
The hydrolysis products of both sunflower oil and tributyrinare less pronounced in an acidic environment to reduce the gastric juice OPA. An increase in the concentration of both sunflower oil and tributyrin in the emulsion with casein contributes to a significant increase in pancreatic juice OPA. At the same time, the effect of tributyrinis less pronounced than when using sunflower oil. At the same time, an increase in the concentration of both tributyrin and sunflower oil to a lesser extent affects the increase in the gastric juice gastric arteries.
About the Authors
O. K. DzhalalovaRussian Federation
Ozoda K. Dzhalalova - doctoral candidate.
Andijan, 170127.
V. A. Aleinik
Russian Federation
Vladimir A. Aleinik - MD, professor, professor of the Department of Normal Physiology.
Andijan, 170127.
M. A. Zhuraeva
Russian Federation
Mohigul A. Juraeva - candidate of medical sciences, associate professor, associate professor of the Department of GP-1, Faculty of Medicine.
Andijan, 170127.
S. M. Babich
Russian Federation
Svetlana M. Babich - Candidate of Medical Sciences, Associate Professor, Head of the Department of Social Hygiene and Health Management.
Andijan, 170127.
Sh. Kh. Khamrakulov
Russian Federation
Sharif K. Khamrakulov - MD, professor, head of the department of pathological physiology.
Andijan, 170127.
References
1. Andreeva Yu. V. The effect of fasting and resumption of feeding on the secretory function of the stomach. Diss., Candidate of Biological Sciences, St. Petersburg, 2007, 140 p.
2. Golding, M., Wooster, T. J., Day, L., Xu, M., Lundin, L., Keogh, J., & Clift on, P. Impact of gastric structuring on the lipolysis of emulsified lipids. Soft matter. 2011. Vol. 7, no. 7, pp. 3513-3523.
3. Macierzanka, A., Sancho, A. I., Mills, E. C., Rigby, N. M., & Mackie, A. R. Emulsification alters simulated gastrointestinal proteolysis of в-casein and в-lactoglobulin. Soft Matter. 2009. Vol. 5, no. 3, pp. 538-550.
4. Mandalari, G., Mackie, A. M., Rigby, N. M., Wickham, M. S., & Mills, E. C. Physiological phosphatidylcholine protects bovine в-lactoglobulin from simulated gastrointestinal proteolysis. Molecular nutrition & food research. 2009. Vol. 53, no. S1, pp. S131-S139.
5. Sarkar A., Goh K. K. T., Singh H. Properties of oil-in-water emulsions stabilized by в-lactoglobulin in simulated gastric fluid as influenced by ionic strength and presence of mucin. Food Hydrocolloids. 2010. Vol. 24, no. 5, pp. 534-541.
6. Sarkar, A., Goh, K. K., Singh, R. P., & Singh, H. Behaviour of an oil-in-water emulsion stabilized by в-lactoglobulin in an in vitro gastric model. Food Hydrocolloids. 2009. Vol. 23, no. 6, pp. 1563-1569.
7. Sklan D., Budowski P., Hurwitz S. Absorption of oleic and taurocholic acids from the intestine of the chick. Interactions and interference by proteins. Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism. 1979. Vol. 573, no. 1, pp. 31-39.
8. Smith, F., Pan, X., Bellido, V., Toole, G. A., Gates, F. K., Wickham, M. S., Mills, E. C. (2015). Digestibility of gluten proteins is reduced by baking and enhanced by starch digestion. Molecular nutrition & food research. 2015. Vol. 59, no. 10, pp. 2034-2043.
Review
For citations:
Dzhalalova O.K., Aleinik V.A., Zhuraeva M.A., Babich S.M., Khamrakulov Sh.Kh. The effect of fats and their hydrolysis products on the proteolytic activity of pancreatic and gastric juices. Experimental and Clinical Gastroenterology. 2020;(7):131-136. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-179-7-131-136