Crohn’s disease in a patient with ciliopathy (cystic disease of the kidneys, liver, lungs), ankylosing spondylitis and secondary polyosteoarthritis, who is on programmed hemodialysis
https://doi.org/10.31146/1682-8658-ecg-181-9-85-88
Abstract
The aim. Discussion of a clinical case of Crohn’s disease in a patient with chronic kidney disease on program hemodialysis.
Materials and methods: the study analyzed the medical history of a patient diagnosed with Crohn’s disease with severe comorbid pathology.
Results. The provoking factors for the development of Crohn’s disease in a patient with ciliopathy (cystic disease of the kidneys, liver, lungs), ankylosing spondylitis, secondary polyosteoarthrosis, undergoing hemodialysis are discussed.
About the Authors
S. N. StyazhkinaRussian Federation
Svetlana N. Styazhkina, Doctor of Medicine, Professor of the Department of faculty surgery
426034, st. Kommunarov, 281, Izhevsk
M. N. Klimentov
Russian Federation
Mikhail N. Klimentov, Candidate of Medical Sciences, Associate professor of the Department of faculty surgery
426034, st. Kommunarov, 281, Izhevsk
T. E. Chernyshova
Russian Federation
Tatyana E. Chernyshova, Doctor of Medicine, Professor of the Department of general practitioner with the course of medical fi rst-aid
426034, st. Kommunarov, 281, Izhevsk
O. A. Neganova
Russian Federation
Olga A. Neganova, graduate student of the Department of general practitioner with the course of medical fi rst-aid
426034, st. Kommunarov, 281, Izhevsk
F. F. Subaev
Russian Federation
Fanis F. Subaev, resident of the Department of faculty therapy with courses in endocrinology and hematology
426034, st. Kommunarov, 281, Izhevsk
A. E. Matusevich
Russian Federation
Anna E. Matusevich, resident of the Department of general practitioner with the course of medical fi rst-aid
426034, st. Kommunarov, 281, Izhevsk
References
1. Стяжкина С. Н. Язвенный колит и болезнь Крона/ С. Н. Стяжкина. – Ижевск, 2018–160 с. Styazhkina S. N. Ulcerative colitis and Crohn›s disease. Styazhkin. Izhevsk, 2018, 160 p.
2. Белоусова, Е. А. Язвенный колит и болезнь Крона / Е. А. Белоусова. – Тверь: «Триада», 2012.-186 с. Belousova, E. A. Ulcerative colitis and Crohn›s disease. Tver, “Triada” Publ., 2012, 186 p.
3. Аксенова М.Е., Катышева О. В. Аутосомно-ре циссивная поликистозная болезнь: современный взгляд на старую проблему // Практика педиатра, 2014. – № 12. – С. 42–46. Aksenova M. E., Katysheva O. V. Autosomal recessive polycystic disease: a modern perspective on an old problem. Practice of a pediatrician, 2014. No. 12, pp.42–46.
4. Tsunoda T, Kakinuma S, Miyoshi M, et al. Loss of fibrocystin promotes interleukin-8-dependent proliferation and CTGF production of biliary epithelium. J Hepatol. 2019 Jul;71(1):143–152. doi: 10.1016/j.jhep.2019.02.024. Epub 2019 Mar 19.
5. Fabris L, Fiorotto R, Spirli C, et al. Pathobiology of inherited biliary diseases: a roadmap to understand acquired liver diseases. Nat Rev Gastroenterol Hepatol. 2019 Aug;16(8):497–511. doi: 10.1038/s41575–019–0156–4.
6. Richards T, Modarage K, Dean C, et al. Atmin modulates Pkhd1 expression and may mediate Autosomal Recessive Polycystic Kidney Disease (ARPKD) through altered non-canonical Wnt/Planar Cell Polarity (PCP) signalling. Biochim Biophys Acta Mol Basis Dis. 2019 Feb 1;1865(2):378–390. doi: 10.1016/j.bbadis.2018.11.003. Epub 2018 Nov 7.
Review
For citations:
Styazhkina S.N., Klimentov M.N., Chernyshova T.E., Neganova O.A., Subaev F.F., Matusevich A.E. Crohn’s disease in a patient with ciliopathy (cystic disease of the kidneys, liver, lungs), ankylosing spondylitis and secondary polyosteoarthritis, who is on programmed hemodialysis. Experimental and Clinical Gastroenterology. 2020;(9):85-88. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-181-9-85-88