Efficacy of Prokinetic Itopride in Type 2 Diabetes Mellitus
https://doi.org/10.31146/1682-8658-ecg-181-9-35-39
Abstract
The constant increase in the incidence of diabetes in the world and the high frequency of lesions of the upper gastrointestinal tract with impaired motor function in this category of patients, on the one hand, worsen the clinical picture, and on the other, reduce the effectiveness of sugar-lowering therapy. Currently, specialists have at their disposal a number of prokinetics that contribute to the restoration of the motor-evacuation function of the stomach, but many of them have many undesirable effects. The aim of our study was to evaluate the effectiveness of itopride hydrochloride in the treatment of patients with chronic gastritis associated with Helicobacter pylori and type 2 diabetes. During the study, both general clinical and more specific research methods were used, in particular, esophagogastroduodenoscopy. According to the results of the study, the use of prokinetics in the treatment of patients with type 2 diabetes mellitus reduces the manifestations of impaired motor-evacuation function of the upper gastrointestinal tract. The results obtained indicate to verify the manifestations of chronic gastritis in patients with type 2 diabetes mellitus and the identification of motor dysfunction and the need for prokinetic therapy.
About the Authors
A. E. Shklyaev
Federal State Budgetary Educational Institution of Higher Education “Izhevsk State Medical Academy” of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Aleksey E. Shklyaev, MD, PhD, Full Proffesor, Rector of medical Academy, Professor of Department of faculty therapy with the courses of endocrinology and hematology
426034, st. Kommunarov, 281, Izhevsk
D. D. Kazarin
Federal State Budgetary Educational Institution of Higher Education “Izhevsk State Medical Academy” of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Daniil D. Kazarin, Postgraduate of Department of faculty therapy with the courses of endocrinology and hematology
426034, st. Kommunarov, 281, Izhevsk
Y. V. Gorbunov
Federal State Budgetary Educational Institution of Higher Education “Izhevsk State Medical Academy” of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Yurii V. Gorbunov, MD, PhD, Full Proffesor, Head of Department of faculty therapy with the courses of endocrinology and hematology
426034, st. Kommunarov, 281, Izhevsk
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Review
For citations:
Shklyaev A.E., Kazarin D.D., Gorbunov Y.V. Efficacy of Prokinetic Itopride in Type 2 Diabetes Mellitus. Experimental and Clinical Gastroenterology. 2020;(9):35-39. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-181-9-35-39
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