Eosinophilic Esophagitis

Abstract

Recent years the number of eosinophilic esophagitis (EE) has increased. The disease is characterized by complex of clinical and histological features, the main of them are dysphagia and eosinophilic infiltration of esophageal mucosa. The etiology and pathogenesis of the disease are poorly studied. Allergy, nutritive factors and genetics are supposed to play leading role in the EE development. The incidence of EE varies worldwide. Only few cases of diagnosed EE were reported in Russia. Our experience includes five cases of EE within 3 years. The aim of the present article is to provide a literature review on the diagnosis and treatment of EE and to present a case of the diagnosed EE in a young man who complained on permanent dysphagia and who was previously treated for supposed gastroesophageal reflux disease and underwent fundoplication for this reason. We achieved complete resolution of the clinical manifestations of the disease.