The State Of Upper Gastrointestinal Mucosa In Patient With Portal Hypertension

E. R. Olevskaya; A. I. Dolgushina; A. N. Tarasov; O. V. Naumenko; T. N. Shamaeva; Yu. I. Klepinina

The State Of Upper Gastrointestinal Mucosa In Patient With Portal Hypertension

E. R. Olevskaya, A. I. Dolgushina, A. N. Tarasov, O. V. Naumenko, T. N. Shamaeva, Yu. I. Klepinina

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Abstract

A study of the state of the mucosa of the upper gastrointestinal tract (GIT) in patient with portal hypertension (PH) is necessary to stratify the risk of bleeding and correct of treatment. The purpose of the study was to study the state and dynamics of changes in mucosa of upper gastrointestinal tract in patient with PH. Materials and methods: Esophagogastroduodenoscopy (EGD) and sessions of endoscopic ligation (EL) were performed in 190 patients with PG. The cause of PG was liver cirrhosis (LC) in 170 cases and portal vein thrombosis (PVT) in 20 cases. Results: Becides varices, portal hypertensive gastropathy and GAVE -syndrome, chronic gastritis, ulcerous lesions, polyps, erosive esophagitis, tumors were found in 48%, 34,7%, 10,5%, 13,4%, 2,1% accordingly. 130 patients bled previously, and 8.6% of them had not variceal cause of bleeding. Conclusions: Pathological changes of mucosa of upper gastrointestinal tract in patients with PG are different and can lead to a bleeding. There are not significant difference in pathology between different types of portal block. Eradication of varices leads to an increase in pathology of the mucosa and PHG. The level of blood pressure in varices correlates with the severity of PHG.