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Experimental and Clinical Gastroenterology

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Spectrum Of Esophageal Motility Disorders In GERD Revealed With The Use Of High Resolution Esophageal Manometry. Single-Center Prospective Trial

Abstract

The aim. To investigate esophageal motility in patients with GERD. Materials and methods. One hundred twenty-five GERD patients were examined. Esophageal motility was studied with the use of high resolution water-perfused catheter (MMS; Solar GI, Netherlands). Results. Normal esophageal motility was found in 70 patients, in 47 patients ineffective esophageal motility (IEM) was found. In 4 cases was revealed absent contractility, in 3 cases distal esophageal spasm (DES), and 1 patient suffered from achalasia type III. Among total group 13 patients had histologically confirmed Barrett esophagus, in 5 of them normal esophageal motility was found and 8 had signs of ineffective motility. Mean EGJ-CI in patients with GERD was 7.17 mmHg x cm (n=125). Conclusion. Patients with GERD have different patterns of esophageal motility. We should consider these differences to better understand the treatment options and prognosis of the disease.

About the Authors

A. A. Smirnov
Public budgetary educational institution of higher education “First Saint-Petersburg State Medical University n. a. I. P. Pavlov” of the Ministry of Healthcare of the Russian Federation
Russian Federation


M. M. Kiriltseva
Public budgetary educational institution of higher education “First Saint-Petersburg State Medical University n. a. I. P. Pavlov” of the Ministry of Healthcare of the Russian Federation
Russian Federation


A. N. Burakov
Public budgetary educational institution of higher education “First Saint-Petersburg State Medical University n. a. I. P. Pavlov” of the Ministry of Healthcare of the Russian Federation
Russian Federation


M. E. Lubchenko
Public budgetary educational institution of higher education “First Saint-Petersburg State Medical University n. a. I. P. Pavlov” of the Ministry of Healthcare of the Russian Federation
Russian Federation


D. I. Vasilevskij
Public budgetary educational institution of higher education “First Saint-Petersburg State Medical University n. a. I. P. Pavlov” of the Ministry of Healthcare of the Russian Federation
Russian Federation


K. D. Semenikhin
Public budgetary educational institution of higher education “First Saint-Petersburg State Medical University n. a. I. P. Pavlov” of the Ministry of Healthcare of the Russian Federation
Russian Federation


S. F. Bagnenko
Public budgetary educational institution of higher education “First Saint-Petersburg State Medical University n. a. I. P. Pavlov” of the Ministry of Healthcare of the Russian Federation
Russian Federation


Review

For citations:


Smirnov A.A., Kiriltseva M.M., Burakov A.N., Lubchenko M.E., Vasilevskij D.I., Semenikhin K.D., Bagnenko S.F. Spectrum Of Esophageal Motility Disorders In GERD Revealed With The Use Of High Resolution Esophageal Manometry. Single-Center Prospective Trial. Experimental and Clinical Gastroenterology. 2018;(10):22-26. (In Russ.)

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ISSN 1682-8658 (Print)