<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-166-6-70-79</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-907</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Особенности терапии больных хронической сердечной недостаточностью в сочетании с алкогольной болезнью печени</article-title><trans-title-group xml:lang="en"><trans-title>Features of the treatment of patients with chronic heart failure in combination with alcoholic liver disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евдокимова</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Evdokimova</surname><given-names>A. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жуколенко</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhukolenko</surname><given-names>L. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евдокимов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Evdokimov</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Томова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tomova</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голикова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Golikova</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стрюк</surname><given-names>Р. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Stryuk</surname><given-names>R. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО МГМСУ им. А. И. Евдокимова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow state university of medicine and dentistry named after A. I. Evdokimov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ООО «Сеть Семейных Медицинских Центров»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Family Medical Center Network</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>20</day><month>06</month><year>2019</year></pub-date><volume>0</volume><issue>6</issue><fpage>70</fpage><lpage>79</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Евдокимова А.Г., Жуколенко Л.В., Евдокимов В.В., Томова А.В., Голикова А.А., Стрюк Р.И., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Евдокимова А.Г., Жуколенко Л.В., Евдокимов В.В., Томова А.В., Голикова А.А., Стрюк Р.И.</copyright-holder><copyright-holder xml:lang="en">Evdokimova A.G., Zhukolenko L.V., Evdokimov V.V., Tomova A.V., Golikova A.A., Stryuk R.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/907">https://www.nogr.org/jour/article/view/907</self-uri><abstract><p>В статье представлен краткий литературный обзор по проблеме коморбидной патологии, а именно хронической сердечной недостаточности (ХСН) на фоне ишемической болезни сердца (ИБС) в сочетании с алкогольной болезнью печени (АБП). Рассмотрены вопросы эпидемиологии, взаимосвязь патогенетических механизмов в развитии и прогрессировании ХСН и АБП. Обсуждаются вопросы оптимизации лечения ХСН и АБП в свете современных рекомендаций и доказательной базы. Особый интерес представляет диагностика такого осложнения как печеночная энцефалопатия (ПЭ), возможность ее обратимости на фоне проводимой терапии с включением L-орнитина-L-аспартата. Приводится клинический случай больного, страдающего ХСН на фоне постинфарктного кардиосклероза в сочетании с токсическим гепатитом.</p></abstract><trans-abstract xml:lang="en"><p>The article provides a brief literature review on the problem of comorbid pathology, namely, chronic heart failure (CHF) in patients with coronary heart disease (CHD) in combination with alcoholic liver disease (ABP). The issues of epidemiology, the relationship of pathogenetic mechanisms in the development and progression of CHF and ABP are considered. The issues of optimizing the treatment of CHF and ABP are discussed in the light of current recommendations and evidence base. Of particular interest is the diagnosis of such a complication as hepatic encephalopathy (PE), the possibility of its reversibility during therapy with the inclusion of L-ornithine-L-aspartate. A clinical case of a patient suffering from heart failure due to post-infarction cardiosclerosis in combination with toxic hepatitis is given.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая сердечная недостаточность</kwd><kwd>ишемическая болезнь сердца</kwd><kwd>алкогольная болезнь печени</kwd><kwd>острый токсический гепатит</kwd><kwd>карведилол</kwd><kwd>L-орнитин-L-аспартат</kwd><kwd>chronic heart failure</kwd><kwd>coronary heart disease</kwd><kwd>alcoholic liver disease</kwd><kwd>acute toxic hepatitis</kwd><kwd>carvedilol</kwd><kwd>L-ornithine-L-aspartate</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
