nogrЭкспериментальная и клиническая гастроэнтерологияExperimental and Clinical Gastroenterology1682-8658«Global Media Technologies»nogr-502Research ArticleКЛИНИЧЕСКАЯ ГАСТРОЭНТЕРОЛОГИЯCLINICAL GASTROENTEROLOGYОСОБЕННОСТИ АКТИНОМИКОЗА КИШЕЧНИКАFEATURES INTESTINAL ACTINOMYCOSISКозловаО. П.KozlovaO. P.olgakozlova07@gmail.comШевяковМ. А.SheviakovM. A.noemail@neicon.ruКлимкоН. Н.KlimkoN. N.noemail@neicon.ruГОУ ДПО СЗГМУ им. И. И. МечниковаРоссияI. Metchnikov North-West State Medical UniversityRussian Federation2017201120170115559Copyright © Козлова О.П., Шевяков М.А., Климко Н.Н., 20172017Козлова О.П., Шевяков М.А., Климко Н.Н.Kozlova O.P., Sheviakov M.A., Klimko N.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.nogr.org/jour/article/view/502

Представлены результаты анализа актиномикоза кишечника у пациентов, находившихся на лечении в микологической клинике НИИ ММ в 2005-2016 гг. Актиномикоз кишечника развивается у людей среднего возраста (медиана - 42 (36,5÷52) года). Типичный фактор риска - аппендэктомия с осложненным течением послеоперационного периода (OR= 3.857[1.527-28.242]). Частая локализация: слепая кишка (64 %) и сальник (64 %). Клинические признаки неспецифичны: интоксикация у 100 %, боль у 91 %, диарея у 73 %, потеря массы тела у 36 %, формирование свищей выявлено у 27 % пациентов. Время от начала заболевания до постановки диагноза варьировало от нескольких недель до двух лет (медиана - 27 +/- 2 дней). Эффективность сочетанного лечения хирургического с длительной антибактериальной терапией составила 94 %.

The results of the single-center study of the intestinal actinomycosis patients, treated at the Research Institute of mycological clinic in 2005-2016. Age of patients from 8 to 81 year, median - 42 (36,5÷52). Risk factors for intestinal actinomycosis were acute appendicitis with perforation (OR= 3.857[1.527-28.242]). Appendix (64 %), omentum (64 %) are the most common abdominal sites of actinomycosis. Patients may present with non-specific symptoms such as fever (100 %), abdominal pain (91 %), weight loss (36 %). The formation of spontaneous draining of purulent material was in 27 % cases. The time from onset to diagnosis varied from a few weeks to two years (median - 27 +/- 2 days). Surgical resection of infected tissue and long-term antibiotic therapy will be effective in the treatment of abdominal actinomycosis - 94 %

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The authors declare that there are no conflicts of interest present.