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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nogr-432</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ ГАСТРОЭНТЕРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL GASTROENTEROLOGY</subject></subj-group></article-categories><title-group><article-title>АНАЛИЗ ГЕНДЕРНЫХ И ВОЗРАСТНЫХ РАЗЛИЧИЙ КАЧЕСТВА ЖИЗНИ БОЛЬНЫХ С СИНДРОМОМ РАЗДРАЖЕННОГО КИШЕЧНИКА</article-title><trans-title-group xml:lang="en"><trans-title>ANALYSIS OF GENDER AND AGE DIFF ERENCES IN THE QUALITY OF LIFE OF PATIENTS WITH IRRITABLE BOWEL SYNDROME</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мнацаканян</surname><given-names>М. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Mnatsakanyan</surname><given-names>M. G.</given-names></name></name-alternatives><email xlink:type="simple">mnatsakanyan08@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Погромов</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Pogromov</surname><given-names>A. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дюкова</surname><given-names>Г. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Dyukova</surname><given-names>G. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тащян</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tashjian</surname><given-names>O. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО Первый МГМУ им. И. М. Сеченова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I. M. Sechenov First Moscow State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>20</day><month>06</month><year>2017</year></pub-date><volume>0</volume><issue>6</issue><fpage>48</fpage><lpage>53</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мнацаканян М.Г., Погромов А.П., Дюкова Г.М., Тащян О.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Мнацаканян М.Г., Погромов А.П., Дюкова Г.М., Тащян О.В.</copyright-holder><copyright-holder xml:lang="en">Mnatsakanyan M.G., Pogromov A.P., Dyukova G.M., Tashjian O.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/432">https://www.nogr.org/jour/article/view/432</self-uri><abstract><p>Цель исследования: Синдром раздраженного кишечника (СРК) негативно влияет на качество жизни (КЖ), связанное со здоровьем. Целью настоящего исследования является сравнительный анализ показателей психического и физического компонентов здоровья у больных СРК в зависимости от возраста, пола пациентов и типа СРК. Материалы и методы: В специализированной гастроэнтерологической клинике у 245 больных СРК было исследовано КЖ с помощью опросника MOS SF-36. Анализ был проведен в 2-х группах больных СРК: до 45 лет (n=125) от 45 лет и старше (n=120). Результаты исследования: У больных с СРК выявлены низкие показатели как физического, так и психического компонентов здоровья. С возрастом значимо снижается КЖ за счет физического компонента здоровья (PH), р&lt;0.05. КЖ по физическому функционированию (FF), эмоциональному (RE) и ролевому функционированию (RP) у женщин старшей возрастной подгруппы ниже, чем, у мужчин, p&lt;0.05. У больных СРК-З показатели КЖ ниже, чем при СРК-Д и СРК-СМ, р&lt;0.05. Заключение: КЖ у больных СРК снижено как в молодом, так и старшем возрасте, преимущественно у женщин и с возрастом еще более снижается. У больных с СРК-З качество жизни ниже, чем при СРК-Д и СРК-СМ.</p></abstract><trans-abstract xml:lang="en"><p>Preamble and aim of the study: Irritable bowel syndrome (IBS) affects health-related quality of life (QоL). The purpose of this study is a comparative analysis of the mental and physical indicators of health conditions IBS patients depending on age, gender of patients and type of IBS. Materials and methods: In a specialized gastroenterology clinic 245 patients with IBS were investigated QoL using a questionnaire MOS SF-36. The analysis was conducted in 2 groups of patients with IBS: up to 45 years (n=125) from 45 years and older (n=120). The results of the study: IBS рatients have low rates of both physical and mental components health. With age significantly reduced QoL, due to the physical component health (PH), p&lt;0.05. QoL by physical (FF), emotional (RE) and role functioning (RP), in the women older age subgroup is lower than in men, p&lt;0.05. QoL indicators of IBS-C patients are lower than in IBS-D and IBS-CM patients, p&lt;0.05. Conclusion: QOL in patients with IBS reduced in younger and older age, predominantly in women and with age even more reduced. IBS-C patients QoL is lower than at IBS-D and IBS-CM.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>синдром раздраженного кишечника</kwd><kwd>качество жизни</kwd><kwd>возраст</kwd><kwd>пол</kwd><kwd>варианты СРК</kwd></kwd-group><kwd-group xml:lang="en"><kwd>irritable bowel syndrome</kwd><kwd>quality of life</kwd><kwd>age</kwd><kwd>gender</kwd><kwd>type of IBS</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lovell RM, Ford AC. 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