nogrЭкспериментальная и клиническая гастроэнтерологияExperimental and Clinical Gastroenterology1682-8658«Global Media Technologies»10.31146/1682-8658-ecg-244-12-103-112nogr-3287Research ArticleСтатьиФакторы риска и некоторые аспекты канцеропревенции рака поджелудочной железыRisk factors and some aspects of pancreatic cancer preventionhttps://orcid.org/0000-0002-9421-5146БыковаА. П.BykovaA. P.vulpesruber@yandex.ruhttps://orcid.org/0000-0002-5056-4504КозловаИ. В.KozlovaI. V.noemail@neicon.ruhttps://orcid.org/0000-0002-0981-1083ТихоноваТ. А.TikhonovaT. A.noemail@neicon.ruhttps://orcid.org/0000-0002-4654-9344ПахомоваА. Л.PakhomovaA. L.noemail@neicon.ruЛекареваЛ. И.LekarevaL. I.noemail@neicon.ruФедеральное государственное бюджетное образовательное учреждение высшего образования «Саратовский государственный медицинский университет им. В.И. Разумовского» Минздрава РоссииРоссияSaratov State Medical University named after V.I. Razumovsky (Razumovsky University)Russian Federation202526022026012103112Copyright © Быкова А.П., Козлова И.В., Тихонова Т.А., Пахомова А.Л., Лекарева Л.И., 20262026Быкова А.П., Козлова И.В., Тихонова Т.А., Пахомова А.Л., Лекарева Л.И.Bykova A.P., Kozlova I.V., Tikhonova T.A., Pakhomova A.L., Lekareva L.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.nogr.org/jour/article/view/3287

Рак поджелудочной железы (РПЖ) - высокозлокачественная опухоль пищеварительной системы с плохим прогнозом. У большинства пациентов с РПЖ диагноз устанавливается на поздней стадии или при метастазировании из-за его агрессивных характеристик и отсутствия типичных ранних симптомов. Это ограничивает возможности лечения и обусловливает низкую пятилетнюю выживаемость в 3-15%. При этом РПЖ встречается относительно редко, и скрининг бессимптомного взрослого населения в настоящее время не считают целесообразным. Цель этого обзора - освещение основных направлений в разработке стратегии раннего скрининга РПЖ: выявление групп высокого риска и соответствующие методы, рекомендуемые для детального исследования в этих когортах.

Pancreatic cancer is a malignant tumor of the digestive system with a poor prognosis. Most patients suffering from pancreatic cancer are diagnosed only at a late stage due to its aggressiveness and lack of early symptoms. This limits treatment options and results in a low five-year survival rate of 3-15%. However, pancreatic cancer is relatively rare, so screening of asymptomatic adults is not currently considered viable. The main purpose of this review is to highlight the main development strategies of early pancreatic cancer screening. This review is an in-depth analysis of the main methods of identifying high-risk groups and the procedures of carrying out a detailed study in these cohorts.

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The authors declare that there are no conflicts of interest present.