nogrЭкспериментальная и клиническая гастроэнтерологияExperimental and Clinical Gastroenterology1682-8658«Global Media Technologies»10.31146/1682-8658-ecg-238-6-93-98nogr-3199Research ArticleОБЗОРREVIEWОсобенности гемореологии и гемостаза при воспалительных заболеваниях кишечника у детей, коррекция измененийFeatures of hemorheology and hemostasis in IBD in children, correction of changeshttps://orcid.org/0000-0002-5526-5597ЦаревВ. А.TsarevV. A.vnkhvc78@mail.ruhttps://orcid.org/0000-0002-1774-0692ФедуловаЭ. Н.FedulovaE. N.noemail@neicon.ruhttps://orcid.org/0000-0002-9008-3860КозловМ. К.KozlovM. K.noemail@neicon.ruhttps://orcid.org/0000-0001-7308-7280ХавкинА. И.KhavkinA. I.noemail@neicon.ruФедеральное государственное бюджетное образовательное учреждение высшего образования «Приволжский исследовательский медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияPrivolzhsky Research Medical UniversityRussian FederationГБУЗ МО «Научно-исследовательский клинический институт детства» Министерства здравоохранения Московской областиРоссияResearch Clinical Institute of Childhood, Ministry of Health of the Moscow RegionRussian Federation202522012026069398Copyright © Царев В.А., Федулова Э.Н., Козлов М.К., Хавкин А.И., 20262026Царев В.А., Федулова Э.Н., Козлов М.К., Хавкин А.И.Tsarev V.A., Fedulova E.N., Kozlov M.K., Khavkin A.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.nogr.org/jour/article/view/3199

Воспалительные заболевания кишечника (ВЗК) являются серьезной проблемой в детской гастроэнтерологии и требуют более глубокого и детального изучения. Патогенез ВЗК основан на генетической предрасположенности, реализация которой происходит под воздействием агрессивных факторов внешней среды и состояния кишечной микрофлоры, что приводит к каскаду воспалительных реакций в стенке кишечника. Однако до настоящего время механизм развития ВЗК остается не до конца изученным, в связи с чем проведение литературного обзора по вопросам особенностей гемореологии и гемостаза у детей с этой патологией является актуальным для последующего изучения этого вопроса c целью оптимизации терапии. Материалы и методы исследования. Поиск источников литературы проводился с использованием библиотечных платформ: PubMed, eLIBRARY. Все источники не более пяти лет давности.

Inflammatory bowel disease (IBD) is a serious problem in pediatric gastroenterology and requires deeper and more detailed study. The pathogenesis of IBD is based on a genetic predisposition, the implementation of which occurs under the influence of aggressive environmental factors and the state of the intestinal microflora, which leads to a cascade of inflammatory reactions in the intestinal wall. However, to date, the mechanism of IBD development remains incompletely understood, and therefore conducting a literature review on the features of hemorheology and hemostasis in children with this pathology is relevant for the subsequent study of this issue in order to optimize therapy. Materials and methods of research. The search for literature sources was carried out using the library platforms: PubMed, eLIBRARY. All sources are no more than five years old.

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The authors declare that there are no conflicts of interest present.