References

nogr

Экспериментальная и клиническая гастроэнтерология

Experimental and Clinical Gastroenterology

1682-8658

«Global Media Technologies»

10.31146/1682-8658-ecg-235-3-236-244

nogr-3152

Research Article

МЕТАБОЛИЧЕСКИЙ СИНДРОМ

METABOLIC SYNDROME

Метаболические фенотипы старческой астении и течение сахарного диабета 2 типа

Metabolic phenotypes of frailty and the course of type 2 diabetes mellitus

Батршина

Л. А.

Batrshina

L. A.

noemail@neicon.ru

https://orcid.org/0000-0003-0027-1786

Булгакова

С. В.

Bulgakova

S. V.

osteoporosis63@gmail.com

Курмаев

Д. П.

Kurmaev

D. P.

noemail@neicon.ru

https://orcid.org/0000-0003-0097-7252

Тренева

Е. В.

Treneva

E. V.

noemail@neicon.ru

https://orcid.org/0009-0006-4531-9682

Косарева

О. В.

Kosareva

O. V.

noemail@neicon.ru

https://orcid.org/0009-0004-6243-6528

Мерзлова

П. Я.

Merzlova

P. Ya.

noemail@neicon.ru

https://orcid.org/0000-0001-8827-4919

Шаронова

Л. А.

Sharonova

L. A.

noemail@neicon.ru

https://orcid.org/0000-0001-6678-6411

Долгих

Ю. А.

Dolgikh

Yu. A.

noemail@neicon.ru

https://orcid.org/0000-0002-9609-2725

Первышин

Н. А.

Pervyshin

N. A.

noemail@neicon.ru

https://orcid.org/0009-0009-2115-0546

Булгаков

А. С.

Bulgakov

A. S.

noemail@neicon.ru

Романенко

Е. А.

Romanenko

E. A.

noemail@neicon.ru

Государственное бюджетное учреждение здравоохранения Самарской области «Самарская городская больница № 6»РоссияSamara Samara City Hospital No. 6Russian Federation

Федеральное государственное бюджетное образовательное учреждение высшего образования «Самарский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияSamara State Medical UniversityRussian Federation

Федеральное государственное бюджетное образовательное учреждение высшего образования «Самарский государственный технический университет»РоссияSamara State Technical UniversityRussian Federation

Федеральное государственное бюджетное образовательное учреждение высшего образования «Самарский государственный технический университет»РоссияSamara State Medical UniversityRussian Federation

2025

29102025

03236244

2025

Батршина Л.А., Булгакова С.В., Курмаев Д.П., Тренева Е.В., Косарева О.В., Мерзлова П.Я., Шаронова Л.А., Долгих Ю.А., Первышин Н.А., Булгаков А.С., Романенко Е.А.

Batrshina L.A., Bulgakova S.V., Kurmaev D.P., Treneva E.V., Kosareva O.V., Merzlova P.Y., Sharonova L.A., Dolgikh Y.A., Pervyshin N.A., Bulgakov A.S., Romanenko E.A.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.nogr.org/jour/article/view/3152

Распространенность сахарного диабета (СД) увеличивается с возрастом. В настоящее время синдром старческой астении (ССА, хрупкость) у больных СД 2 типа считается дополнительным осложнением к традиционным микро- и макрососудистым. ССА вызывает изменения состава тела и метаболизма, формируя определенные фенотипы, которые влияют на течение СД 2 типа, выбор целевых показателей гликемии и сахароснижающей терапии. Анализу метаболических изменений и фенотипов, связанных с ССА, их влиянию на течение СД 2 типа, выбор сахароснижающей терапии и целевых значений гликемии посвящена данная статья.

The prevalence of diabetes mellitus (DM) increases with age. Currently, frailty syndrome (FSS, frailty) in patients with type 2 DM is considered an additional complication to traditional micro- and macrovascular complications. FSS causes changes in body composition and metabolism, forming certain phenotypes that affect the course of type 2 DM, the choice of target glycemic values and hypoglycemic therapy. This article is devoted to the analysis of metabolic changes and phenotypes associated with FSS, their impact on the course of type 2 DM, the choice of hypoglycemic therapy and target glycemic values.

сахарный диабетсиндром старческой астениипожилые людисахароснижающая терапиягликемия

diabetes mellitusfrailty syndromeelderly peoplehypoglycemic therapyglycemia

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The authors declare that there are no conflicts of interest present.