References

nogr

Экспериментальная и клиническая гастроэнтерология

Experimental and Clinical Gastroenterology

1682-8658

«Global Media Technologies»

10.31146/1682-8658-ecg-235-3-35-43

nogr-3132

Research Article

МЕТАБОЛИЧЕСКИЙ СИНДРОМ

METABOLIC SYNDROME

Детские истоки хронических заболеваний взрослых: в фокусе - ожирение и метаболический синдром

Children’s origins of chronic diseases in adults: focus on obesity and metabolic syndrome (literature review)

https://orcid.org/0000-0003-0941-9871

Мигачёва

Н. Б.

Migacheva

N. B.

nbmigacheva@gmail.com

https://orcid.org/0000-0003-3329-6445

Скворцова

О. В.

Skvortsova

O. V.

noemail@neicon.ru

Федеральное государственное бюджетное образовательное учреждение высшего образования «Самарский государственный медицинский университет» Министерства здравоохранения Российской Федерации; Государственное бюджетное учреждение здравоохранения «Самарская областная детская клиническая больница им. Н.Н. Ивановой»РоссияSamara State Medical University; Samara Regional Children’s Clinical Hospital named after N.N. IvanovaRussian Federation

2025

29102025

033543

2025

Мигачёва Н.Б., Скворцова О.В.

Migacheva N.B., Skvortsova O.V.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.nogr.org/jour/article/view/3132

В настоящее время проблема ожирения и метаболического синдрома, входящих в группу хронических неинфекционных заболеваний, приобрела серьезное медико-социальное значение и глобальный масштаб в связи с неуклонным повсеместным ростом распространенности, что заставляет ученых искать причины таких негативных эпидемиологических трендов. В последние годы в круг наиболее интересных вопросов, обсуждаемых медицинским сообществом, попала концепция раннего программирования, основой которой является постулат о том, что истоки большинства хронических заболеваний взрослых формируются в детском возрасте. В настоящем обзоре представлены современные научные данные, подтверждающие концепцию ранних истоков хронических заболеваний с фокусом на ожирение и метаболических синдром. Авторы рассматривают ключевые факторы, определяющие особенности метаболических процессов, лежащих в основе формирования здоровья человека или предрасполагающих к развитию метаболических заболеваний, особенно в ранние периоды развития, акцентируя внимание на факторах риска ожирения и возможных направлениях профилактических вмешательств.

Currently, the problem of obesity and metabolic syndrome, which are part of the group of chronic non-infectious diseases, has acquired serious medical and social significance and a global scale due to the steady worldwide increase in prevalence, which forces scientists to look for the reasons for such negative epidemiological trends. In recent years, the concept of early programming, which is based on the postulate that the origins of most chronic diseases in adults are formed in childhood, has become one of the most interesting issues discussed in the medical community. This review presents current scientific evidence supporting the concept of the early origins of chronic diseases, with a focus on obesity and metabolic syndrome. The authors consider the key factors that determine the characteristics of metabolic processes that underlie the formation of human health or predispose to the development of metabolic diseases, especially in the early periods of development, focusing on risk factors for obesity and possible areas of preventive interventions.

ожирениеметаболический синдромхронические неинфекционные заболеваниядетиранние истоки

obesitymetabolic syndromechronic non-infectious diseaseschildrenearly origins

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The authors declare that there are no conflicts of interest present.