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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-234-2-187-193</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-3097</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Лечение перианальных проявлений болезни Крона</article-title><trans-title-group xml:lang="en"><trans-title>Treatment of perianal manifestations of Crohn's disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-3200-6261</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитина</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitina</surname><given-names>I. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3363-6841</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Леонтьев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Leontyev</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6152-5693</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сытьков</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sytkov</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9439-9873</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Данилов</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Danilov</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7308-7280</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хавкин</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Khavkin</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3364-610X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яблокова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yablokova</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-0176-4588</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орлюк</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Orlyuk</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-6"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ Московский Клинический Научный Центр имени А.С. Логинова ДЗМ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Clinical Scientific Center named after Loginov MHD</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ Московский Клинический Научный Центр имени А.С. Логинова ДЗМ; Московский финансово-промышленный университет «Синергия»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Clinical Scientific Center named after Loginov MHD; Moscow Financial and Industrial University «Synergy»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Российский университет медицины» Министерства здравоохранения Российской Федерации; Федеральное государственное бюджетное учреждение «Федеральный научно-клинический центр детей и подростков Федерального медико-биологического агентства» (ФГБУ «ФНКЦ детей и подростков ФМБА России»)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian University of Medicine; Federal Scientific and Clinical Center for Children and Adolescents of the Federal Medical and Biological Agency</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Федеральное государственное автономное образовательное учреждение высшего образования «Белгородский государственный исследовательский университет» Министерства науки и высшего образования Российской Федерации; ГБУЗ МО «Научно-исследовательский клинический институт детства» Министерства здравоохранения Московской области</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Belgorod State Research University. Ministry of Science and Higher Education of the Russian Federation; Research Clinical Institute of Childhood, Ministry of Health of the Moscow Regio</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ГБУЗ МО «Научно-исследовательский клинический институт детства» Министерства здравоохранения Московской области; Федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Clinical Institute of Childhood, Ministry of Health of the Moscow Regio; Sechenov University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>Московский финансово-промышленный университет «Синергия»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Financial and Industrial University «Synergy»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>31</day><month>08</month><year>2025</year></pub-date><volume>0</volume><issue>2</issue><fpage>187</fpage><lpage>193</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Никитина И.А., Леонтьев А.В., Сытьков В.В., Данилов М.А., Хавкин А.И., Яблокова Е.А., Орлюк М.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Никитина И.А., Леонтьев А.В., Сытьков В.В., Данилов М.А., Хавкин А.И., Яблокова Е.А., Орлюк М.А.</copyright-holder><copyright-holder xml:lang="en">Nikitina I.A., Leontyev A.V., Sytkov V.V., Danilov M.A., Khavkin A.I., Yablokova E.A., Orlyuk M.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/3097">https://www.nogr.org/jour/article/view/3097</self-uri><abstract><p>В настоящее время лечение пациентов с перианальными проявлениями болезни Крона представляет собой сложную задачу, требующую комплексного подхода. Существующие методы хирургической коррекции, зачастую, носят лишь временный характер, показатель частоты рецидивов заболевания по-прежнему остается на высоком уровне. Неудовлетворительные результаты лечения, особенно в отдаленном послеоперационном периоде, малое число клинических наблюдений в опубликованных научных работах, посвященных лечению перианальных свищей на фоне болезни Крона, отсутствие единой тактики лечения этих пациентов, а также низкая достоверность результатов, определяют потребность дальнейших исследований.</p></abstract><trans-abstract xml:lang="en"><p>Currently, the treatment of patients with perianal manifestations of Crohn's disease is a complex task that requires an integrated approach. Existing methods of surgical correction are often only temporary, the rate of relapse of the disease remains high. Unsatisfactory treatment results, especially in the late postoperative period, a small number of clinical observations in published scientific papers devoted to the treatment of perianal fistulas against the background of Crohn's disease, the lack of a unified treatment strategy for these patients, as well as the low reliability of the results, determine the need for further research.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Перианальные проявления болезни Крона</kwd><kwd>обзор литературы</kwd><kwd>сфинктеросберегающие операции</kwd><kwd>стромально-васкулярная фракция (SVF)</kwd><kwd>обогащенная тромбоцитами плазма (PRP)</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Perianal manifestations of Crohn's disease</kwd><kwd>literature review</kwd><kwd>sphincter-preserving operations</kwd><kwd>stromal vascular fraction (SVF)</kwd><kwd>platelet-rich plasma (PRP)</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Gaertner W.B., Burgess P.L., Davids J.S., Lightner A.L., Shogan B.D., Sun M.Y., Steele S.R., Paquette I.M., Feingold D.L.; Clinical Practice Guidelines Committee of the American Society of Colon and Rectal Surgeons. 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