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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-237-5-24-29</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-3031</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ХИРУРГИЧЕСКАЯ ГАСТРОЭНТЕРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SURGICAL GASTROENTEROLOGY</subject></subj-group></article-categories><title-group><article-title>Оперативная эндоскопия у пациентов с субэпителиальными новообразованиями пищевода</article-title><trans-title-group xml:lang="en"><trans-title>Interventional endoscopy in esophageal subepithelial tumors</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3690-1316</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дробязгин</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Drobyazgin</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">evgenyidrob@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6795-6678</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чикинев</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Chikinev</surname><given-names>Yu. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7320-5141</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коробейников</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Korobeinikov</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1800-6422</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полякевич</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Polyakevich</surname><given-names>A. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3810-2788</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пешкова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Peshkova</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1737-7747</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Штофин</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Stofin</surname><given-names>S. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Новосибирский государственный медицинский университет» Минздрава Росси; Государственное бюджетное учреждение здравоохранения Новосибирской области «Государственная Новосибирская областная клиническая больница»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University; State Novosibirsk Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Государственное бюджетное учреждение здравоохранения Новосибирской области «Государственная Новосибирская областная клиническая больница»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Novosibirsk Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Новосибирский государственный медицинский университет» Минздрава Росси</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>18</day><month>07</month><year>2025</year></pub-date><volume>0</volume><issue>5</issue><fpage>24</fpage><lpage>29</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Дробязгин Е.А., Чикинев Ю.В., Коробейников А.В., Полякевич А.С., Пешкова И.В., Штофин С.Г., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Дробязгин Е.А., Чикинев Ю.В., Коробейников А.В., Полякевич А.С., Пешкова И.В., Штофин С.Г.</copyright-holder><copyright-holder xml:lang="en">Drobyazgin E.A., Chikinev Y.V., Korobeinikov A.V., Polyakevich A.S., Peshkova I.V., Stofin S.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/3031">https://www.nogr.org/jour/article/view/3031</self-uri><abstract><p>Цель исследования. Оценка результатов эндоскопических операций у пациентов с подслизистыми опухолями пищевода на основании данных одного центра. Материалы и методы. С 2017 по 2025 год эндоскопические вмешательства при субэпителиальных опухолях пищевода выполнены 72 пациентам с субэпителиальными опухолями пищевода: эндоскопическая диссекция новообразования трем пациентам, тоннельные эндоскопические вмешательства у 67 пациентов в возрасте от 18 до 67 лет (средний возраст 47,45±12,2 лет). Среди пациентов преобладали женщины - 45, мужчин было - 27. Результаты. Длительность оперативного вмешательства в тоннельном варианте составляла от 45 до 210 минут (в среднем значении 116,56 минут). Опухоли были удалены полностью. При локализации опухоли в II эхослое, длительность вмешательства не превышала 30 минут. Сложности были у семи пациентов при плексиморфных опухолях. Изменение хода вмешательства было в трех случаях - опухоли были удалены с фрагментом слизистой оболочки, а образовавшиеся дефекты клипированы. Фрагментирование опухоли перед ее извлечением при помощи петли было предпринято нами в семи случаях при размерах опухолей более 4 см. Осложнений во время операции и в послеоперационном периоде не наблюдали. Во всех случаях опухоли были полностью удалены. По результатам патоморфологического и иммуногистохимического исследования у большинства (66-94,28%) пациентов диагностирована лейомиома, у двух (2,85%) гастроинтестинальная стромальная опухоль с высоким митотическим индексом, у двух (2,85%) опухоль Абрикосова. Выводы. Эндоскопические операции при подслизистых опухолях пищевода и пищеводно-желудочного перехода - высокоэффективны и безопасны. Обязательным является проведение эндоскопического ультразвукового исследования для визуализации новообразования, определения истинных размеров, слоя стенки пищевода и для типирования перед планируемой интервенцией, но всегда позволяет определить истинный тип опухоли. Возможно безопасное применение туннельных эндоскопических вмешательств при размерах опухоли более 4 см с выделением и извлечением опухоли, в том числе путем ее фрагментирования. Осложнения, возникающие во время оперативного вмешательства, могут быть успешно устранены с применением гибких эндоскопов.</p></abstract><trans-abstract xml:lang="en"><p>The aim of the study - evaluate the one center results of endoscopic interventions in patients with esophageal submucosal tumors. Materials and methods. From 2017 to 2024, endoscopic interventions for esophageal subepithelial tumors were performed in 72 patients: endoscopic dissection of the neoplasm in 3 patients, tunnel endoscopic interventions were performed in 67 patients aged 18 to 67 years (mean age 47.45 ± 12.2 years) (women - 45, men 27). Results. The duration of the tunnel surgery ranged from 45 to 210 minutes (on average 116.56 minutes). The tumors were completely removed. When the tumor was localized in the II echo layer, the duration of the intervention did not exceed 30 minutes. We had difficulties in treatment 7 patients with pleximorphic tumors. The intervention plan was changed in 3 cases - the tumors were removed and clipping of mucosa defect was perfomed. Fragmentation of the tumor before its extraction was used in 7 cases with tumor sizes of more than 4 cm. We didn’t have complications during the operation and postoperative period. In all cases, the tumors were completely removed. According to the results of pathomorphological and immunohistochemical studies, leiomyoma was diagnosed in 68-94.44% of patients, gastrointestinal stromal tumor with a high mitotic index in 2 (2.77%), and Abrikosov tumor in 2 (2.77%). Conclusions. Interventions for submucosal tumors of the esophagus and esophagogastric junction are highly effective and safe. Endoscopic ultrasound examination is mandatory to tumor visualization, determine the true size, the esophageal wall layer. It always allows to determine the true type of tumor. Safe use of tunnel endoscopic interventions is possible for tumors larger than 4 cm with isolat</p></trans-abstract><kwd-group xml:lang="ru"><kwd>подслизистые опухоли пищевода</kwd><kwd>тоннельные вмешательства</kwd><kwd>лейомиома пищевода</kwd><kwd>эндоскопия</kwd><kwd>эндоскопический ультразвук</kwd></kwd-group><kwd-group xml:lang="en"><kwd>esophageal submucosal tumor</kwd><kwd>tunnel interventions</kwd><kwd>esophageal leiomyoma</kwd><kwd>endoscopy</kwd><kwd>endoscopic ultrasound</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Wang Z, Zheng Z, Wang T. et al. 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