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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-230-10-130-136</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-3009</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ХИРУРГИЧЕСКАЯ ГАСТРОЭНТЕРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SURGICAL GASTROENTEROLOGY</subject></subj-group></article-categories><title-group><article-title>Опыт применения индоцианина зеленого и низкочастотной пьезотромбоэластографии для оценки печеночной недостаточности у пациента с опухолью периампулярной зоны, осложненной механической желтухой</article-title><trans-title-group xml:lang="en"><trans-title>The experience of using indocyanine and low-frequency piezothromboelastography to assess liver failure in a patient with a tumor of the periampular zone complicated by obstructive jaundice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1056-3168</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенцов</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sementson</surname><given-names>K. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6411-040X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бояринов</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Boyarinov</surname><given-names>D. Yu.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5879-2093</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мянзелин</surname><given-names>М. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Myanzelin</surname><given-names>M. N.</given-names></name></name-alternatives><email xlink:type="simple">mn_myanzelin@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-4429-4887</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фоменко</surname><given-names>Е. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Fomenko</surname><given-names>E. E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-6272-0130</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исаева</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Isaeva</surname><given-names>P. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6399-6963</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кошелев</surname><given-names>Т. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Koshelev</surname><given-names>T. E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургское государственное бюджетное учреждение здравоохранения «Госпиталь для ветеранов войн»; Федеральное государственное бюджетное образовательное учреждение высшего образования «Северо-Западный государственный медицинский университет имени И.И. Мечникова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Hospital for Veterans of Wars; North-Western State Medical University named after I.I. Mechnikov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Санкт-Петербургское государственное бюджетное учреждение здравоохранения «Госпиталь для ветеранов войн»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Hospital for Veterans of Wars</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Северо-Западный государственный медицинский университет имени И.И. Мечникова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North-Western State Medical University named after I.I. Mechnikov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>10</day><month>12</month><year>2024</year></pub-date><volume>0</volume><issue>10</issue><fpage>130</fpage><lpage>136</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Семенцов К.В., Бояринов Д.Ю., Мянзелин М.Н., Фоменко Е.Е., Исаева П.В., Кошелев Т.Е., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Семенцов К.В., Бояринов Д.Ю., Мянзелин М.Н., Фоменко Е.Е., Исаева П.В., Кошелев Т.Е.</copyright-holder><copyright-holder xml:lang="en">Sementson K.V., Boyarinov D.Y., Myanzelin M.N., Fomenko E.E., Isaeva P.V., Koshelev T.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/3009">https://www.nogr.org/jour/article/view/3009</self-uri><abstract><p>Панкреатодуоденальная резекция - это единственный радикальный хирургический метод лечения пациентов со злокачественными опухолями периампулярной зоны. Механическая желтуха в большинстве случаев является первым проявлением заболевания. Больные этой категории часто истощены, имеют нарушения функции печени и подвержены высокому риску периоперационных осложнений. Одним из способов решения данного вопроса является предоперационное дренирование желчных путей. В то же время существуют противоречивые взгляды на оптимальные сроки выполнения радиальной операции после билиарного дренирования. В статье мы приводим опыт применения дополнительных методов для оценки функции печени у пациента с механической желтухой, которые позволяют оптимизировать стратегию лечения. Пациент 71 год, с диагнозом аденокарционома большого дуоденального сосочка, осложненная кишечным кровотечением и механической желтухой. Больному на первом этапе выполнена селективная эмболизация ветвей a. gastroduodenalis, и чрезкожно-чрезпеченочное дренирование желчевыводях путей. В послеоперационном периоде продолжалась активная инфузионная, дезинтоксикационная терапия. На 10 сутки проведена оценка функционального состояния печени и системы гемостаза с помощью низкочастотной пьезотромбоэлатостографии и оценки элиминации индоцианин зеленого: купированы структурная и хронометрическая гипокоагуляция, скорость плазменной элиминации увеличилась в 5 раз. На 11 сутки пациенту выполнена панкреатодуоденальная резекция, послеоперационный период протекал на фоне формирования биохимической фистулы. Таким образом, оценка элиминации индоцианин зеленого и низкочастотная пьезотромбоэластография могут быть использованы в комплексной оценке состояния пациента при выборе тактики хирургического лечения больных с опухолями панкреатодуоденальной зоны, осложненных механической желтухой.</p></abstract><trans-abstract xml:lang="en"><p>Pancreaticoduodenal resection is the only radical surgical method for the treatment of patients with malignant periampullary tumors. Mechanical jaundice in most cases is the first manifestation of the disease. Patients in this category are often emaciated, have impaired liver function and are at high risk of perioperative complications. One of the ways to solve this issue is preoperative drainage of biliary tract. At the same time, there are contradictory views on the optimal timing of radial surgery after biliary drainage. In this article we present our experience of using additional methods to assess liver function in a patient with mechanical jaundice, which allow us to optimize the treatment strategy. A 71-year-old patient diagnosed with adenocarcinoma of the large duodenal papilla complicated by intestinal bleeding and mechanical jaundice. Selective embolization of a. gastroduodenalis branches and percutaneous transhepatic biliary drainage were performed at the first stage. In the postoperative period active infusion and detoxification therapy was continued. On the 10th day the functional state of the liver and hemostasis system was evaluated using low-frequency piezothromboelatostography and evaluation of indocyanine green elimination: structural and chronometric hypocoagulation were eliminated, plasma elimination rate increased 5 times. On the 11th day the patient underwent pancreaticoduodenal resection, the postoperative period proceeded against the background of biochemical fistula formation. Thus, evaluation of indocyanine green elimination and low-frequency piezothromboelastography can be used in complex assessment of the patient’s condition when choosing the tactics of surgical treatment of patients with pancreaticoduodenal tumors complicated by mechanical jaundice.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>механическая желтуха</kwd><kwd>индоцианин зеленый</kwd><kwd>опухоль периампулярной зоны</kwd><kwd>панкреатодуоденальная резекция</kwd><kwd>низкочастотная пьезотромбоэластография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obstructive jaundice</kwd><kwd>indocyanine green</kwd><kwd>periampular tumor</kwd><kwd>pancreatoduodenal resection</kwd><kwd>low-frequency piezothromboelastography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Blacker S., Lahiri R.P., Phillips M. et al. 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