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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-229-9-119-125</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-2893</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ ГАСТРОЭНТЕРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL GASTROENTEROLOGY</subject></subj-group></article-categories><title-group><article-title>Саркопения и ГЭРБ</article-title><trans-title-group xml:lang="en"><trans-title>Sarcopenia and GERD</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4160-8154</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шавкута</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shavkuta</surname><given-names>G. V.</given-names></name></name-alternatives><email xlink:type="simple">semmed@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8736-5851</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лазебник</surname><given-names>Л. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Lazebnik</surname><given-names>L. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8844-2465</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Туркина</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Turkina</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Ростовский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rostov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Российский университет медицины» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian University of Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО «Волгоградский государственный медицинский университет», Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Volgograd State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>06</day><month>03</month><year>2025</year></pub-date><volume>0</volume><issue>9</issue><fpage>119</fpage><lpage>125</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шавкута Г.В., Лазебник Л.Б., Туркина С.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Шавкута Г.В., Лазебник Л.Б., Туркина С.В.</copyright-holder><copyright-holder xml:lang="en">Shavkuta G.V., Lazebnik L.B., Turkina S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/2893">https://www.nogr.org/jour/article/view/2893</self-uri><abstract><p>По оценкам экспертов, саркопения, как генерализованное прогрессирующее расстройства функции скелетной мускулатуры, в ближайшем будущем приобретет статус общемировой проблемы, что связывают с увеличением продолжительности жизни людей, а значимость ее основных фенотипов (саркопеническое ожирения, кахексия) не вызывает сомнений. Результаты метаанализа указывают, что саркопеническое ожирение является значимым предиктором смертности от всех причин среди пожилых людей, особенно госпитализированных пациентов. Кахексия - предиктор смертности при онкозаболеваниях. Особый интерес вызывают данные о тесной связи ГЭРБ и различных фенотипов саркопении. В представленном обзоре продемонстрированы имеющиеся на сегодняшний день данные, подтверждающие эту взаимосвязь. Показана важность ранней диагностики саркопении, саркопенического ожирения и кахексии с целью возможной коррекции этого состояния и снижения показателей смертности. особенно среди пожилых людей.</p></abstract><trans-abstract xml:lang="en"><p>According to experts, sarcopenia, as a generalized progressive disorder of skeletal muscle function, will acquire the status of a global problem in the near future, which is associated with an increase in human life expectancy, and the significance of its main phenotypes (sarcopenic obesity, cachexia) is beyond doubt. The results of the meta-analysis indicate that sarcopenic obesity is a significant predictor of all-cause mortality among the elderly, especially hospitalized patients. Cachexia is a predictor of mortality in cancer. Of particular interest are the data on the close relationship between GERD and various phenotypes of sarcopenia. The presented review demonstrates the data available to date confirming this relationship. The importance of early diagnosis of sarcopenia, sarcopenic obesity and cachexia is shown in order to possibly correct this condition and reduce mortality rates. especially among the elderly.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>саркопения</kwd><kwd>саркопеническое ожирение</kwd><kwd>кахексия</kwd><kwd>миокины</kwd><kwd>гастроэзофагеальная рефлюксная болезнь</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sarcopenia</kwd><kwd>sarcopenic obesity</kwd><kwd>cachexia</kwd><kwd>myokines</kwd><kwd>gastroesophageal reflux disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Dikova T.S., Zatsepina A. Yu., Fedorinov D.S., Lyadov V.K. Sarcopenia, sarcopenic obesity, myosteatosis as factors of unfavorable prognosis in tumors of the gastrointestinal tract: literature review. Sovremennaya Onkologiya = Modern Oncology. 2021;23(1):141-147. 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