nogrЭкспериментальная и клиническая гастроэнтерологияExperimental and Clinical Gastroenterology1682-8658«Global Media Technologies»nogr-288Research ArticleЛЕКЦИЯLECTIONПАНКРЕАТИТ У БЕРЕМЕННЫХ: ТАКТИКА ВЕДЕНИЯ ПАЦИЕНТОКPANCREATITIS IN PREGNANCY: CASE MANAGMENTМаринкинИ. О.MarinkinI. O.rector@ngmu.ruСоколоваТ. М.SokolovaT. M.noemail@neicon.ruКиселеваТ. В.KiselevaT. V.noemail@neicon.ruКулешовВ. М.KuleshovV. M.noemail@neicon.ruМакаровК. Ю.MakarovK. Yu.noemail@neicon.ruЯкимоваА. В.YakimovaA. V.noemail@neicon.ruАйдагуловаС. В.AidagulovaS. V.noemail@neicon.ruФГБОУ ВО НГМУ Минздрава России - Федеральное государственное бюджетное образовательное учреждение высшего образования «Новосибирский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияFSBEF HE NSMU HMR - Federal State Budget Educational Foundation of the High Education «Novosibirsk State Medical University» of the Health Ministry of RussiaRussian Federation201620092016099197Copyright © Маринкин И.О., Соколова Т.М., Киселева Т.В., Кулешов В.М., Макаров К.Ю., Якимова А.В., Айдагулова С.В., 20162016Маринкин И.О., Соколова Т.М., Киселева Т.В., Кулешов В.М., Макаров К.Ю., Якимова А.В., Айдагулова С.В.Marinkin I.O., Sokolova T.M., Kiseleva T.V., Kuleshov V.M., Makarov K.Y., Yakimova A.V., Aidagulova S.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.nogr.org/jour/article/view/288

Цель обзора - обобщение современных данных о хроническом и остром панкреатите для улучшения диагностики и лечения женщин в период беременности, которая осложняет дифференциальную диагностику патологии гепатопанкреатобилиарной системы. Представлены особенности заболеваемости, этиологии, патогенеза и оценка тяжести клинических проявлений обострения панкреатита у беременных женщин. Сделан акцент на его наиболее частой причине - желчнокаменной болезни с развитием билиарного панкреатита. Проанализирован опыт применения у беременных пациенток методов визуализации - эндоскопического УЗИ, магнитно-резонансной холангиопанкреатографии (МРХПГ) и эндоскопической ретроградной холангиопанкреатографии (ЭРХПГ), а также методов лечения, которые включают в себя эндоскопическую сфинктеротомию, экстракцию камня из общего желчного протока и лапароскопическую холецистэктомию. Рекомендации основаны на мнении экспертов и не подтверждены рандомизированными контролируемыми исследованиями. При этом более активная тактика ведения пациенток позволяет своевременно диагностировать и эффективно лечить панкреатит, в том числе билиарный, что способствует резкому снижению показателей материнской и перинатальной смертности.

The purpose of the review is to summarise the current data on chronic and acute pancreatitis with the goal to improve the diagnostics and treatment of women during pregnancy, which complicates differential diagnosis of hepatopancreatobiliary system pathology. The features of the incidence, etiology, pathogenesis and evaluation of the severity of the clinical manifestations of acute pancreatitis in pregnant women are given. It is emphasis that the most frequent its reason is the gallstones following by the biliary pancreatitis. The experience of use in pregnant patients imaging methods - endoscopic ultrasound, magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography, as well as treatments that include endoscopic sphincterotomy, stone extraction from the common bile duct and laparoscopic cholecystectomy. The recommendations are based on expert opinions and are not supported by randomized controlled trials. Nevertheless more active clinical management allows to diagnose and treat effectively pancreatitis, including biliary etiology, which contributes to a sharp decline in maternal and perinatal mortality.

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The authors declare that there are no conflicts of interest present.