nogrЭкспериментальная и клиническая гастроэнтерологияExperimental and Clinical Gastroenterology1682-8658«Global Media Technologies»10.31146/1682-8658-ecg-228-8-258-272nogr-2870Research ArticleКЛИНИЧЕСКИЕ НАБЛЮДЕНИЯCLINICAL CASESОценка качества жизни пациентов с воспалительными заболеваниями кишечника в зависимости от проводимой лекарственной терапииAssessment of the quality of life of patients with inflammatory bowel diseases depending on the drug therapy performedhttps://orcid.org/0000-0001-7308-7280ХавкинА. И.KhavkinA. I.noemail@neicon.ruhttps://orcid.org/0000-0001-8364-6066НиколайчукК. М.NikolaychukK. M.noemail@neicon.ruhttps://orcid.org/0009-0001-7803-7917НиколаеваВ. Д.NikolaevaV. D.noemail@neicon.ruhttps://orcid.org/0009-0002-9228-2350ВеременкоА. С.VeremenkoA. S.noemail@neicon.ruhttps://orcid.org/0009-0002-7317-6077ЛевченкоИ. Д.LevchenkoI. D.noemail@neicon.ruhttps://orcid.org/0009-0004-1880-9585ПлатоноваП. Я.PlatonovaP. Ya.noemail@neicon.ruhttps://orcid.org/0009-0008-7479-8277НовиковаМ. Ф.NovikovaM. F.noemail@neicon.ruhttps://orcid.org/0009-0004-1138-6049ТумасА. С.TumasA. S.noemail@neicon.ruhttps://orcid.org/0009-0003-0793-4236ВергуноваЕ. Е.VergunovaE. E.noemail@neicon.ruhttps://orcid.org/0000-0003-3606-4068ШрайнерЕ. В.ShraynerE. V.sch704@icloud.comhttps://orcid.org/0009-0000-5888-0651ЛукичевД. А.LukichevD. A.noemail@neicon.ruГБУЗ МО «Научно-исследовательский клинический институт детства Министерства здравоохранения Московской области»; Белгородский государственный исследовательский университетРоссияResearch Clinical Institute of Childhood, Ministry of Health of the Moscow Region; Belgorod State Research UniversityRussian FederationНовосибирский государственный университетРоссияNovosibirsk State UniversityRussian FederationНовосибирский государственный университет; Институт химической биологии и фундаментальной медицины СО РАНРоссияNovosibirsk State University; Institute of Chemical Biology and Fundamental Medicine of the SB RASRussian Federation20240302202508258272Copyright © Хавкин А.И., Николайчук К.М., Николаева В.Д., Веременко А.С., Левченко И.Д., Платонова П.Я., Новикова М.Ф., Тумас А.С., Вергунова Е.Е., Шрайнер Е.В., Лукичев Д.А., 20252025Хавкин А.И., Николайчук К.М., Николаева В.Д., Веременко А.С., Левченко И.Д., Платонова П.Я., Новикова М.Ф., Тумас А.С., Вергунова Е.Е., Шрайнер Е.В., Лукичев Д.А.Khavkin A.I., Nikolaychuk K.M., Nikolaeva V.D., Veremenko A.S., Levchenko I.D., Platonova P.Y., Novikova M.F., Tumas A.S., Vergunova E.E., Shrayner E.V., Lukichev D.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.nogr.org/jour/article/view/2870

В данной работа подробно рассматривается влияние воспалительных заболеваний кишечника (ВЗК) на качество жизни пациентов. С целью оценки КЖ пациентов были разработан ряд специфических и общих инструментов, позволяющих оценить КЖ у больных ВЗК. Согласно данным полученным в ряде клинических исследований ВЗК значимо снижают качество жизни пациентов в сравнении с здоровыми людьми. Более того КЖ напрямую связано с формой и степень активности ВЗК. Так более худшее качество жизни ассоциировано с болезнью Крона и активной стадией заболевания. Однако в стадию ремиссии КЖ у пациентов с болезнью Крона (БК) и язвенным колитом (ЯК) не имеют статистически значимых отличий. Помимо этого, для КЖ жизни пациентов с ЯК большое значение имеет диета и образ жизни. Крайне важным звеном позволяющем значимо улучшить КЖ пациентов является консервативная терапия большое значение в которой играют таргетные препараты. Последние выраженно повышают КЖ пациентов с ВЗК, способствуя переходу ВЗК из активной формы в стадию ремиссии.

This paper details the impact of inflammatory bowel disease (IBD) on patients’ quality of life. In order to assess patients’ quality of life, a number of specific and general tools have been developed to assess quality of life in patients with IBS. According to the data obtained in a number of clinical studies, IBS significantly reduces the quality of life of patients compared to healthy people. Moreover, the quality of life is directly related to the form and degree of ICD activity. Thus, worse quality of life is associated with Crohn’s disease and active stage of the disease. However, in the remission stage, the quality of life in patients with Crohn’s disease (CD) and ulcerative colitis (UC) do not have statistically significant differences. In addition, diet and lifestyle are of great importance for the QOL of patients with UC. Conservative therapy is an extremely important link that allows to significantly improve the life quality of patients, in which targeting pre-drugs play an important role. The latter significantly improve the QOL of patients with ICD, contributing to the transition of ICD from the active form to remission.

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The authors declare that there are no conflicts of interest present.