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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nogr-286</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>ХОЛЕСТАЗ У БЕРЕМЕННЫХ</article-title><trans-title-group xml:lang="en"><trans-title>CHOLESTASIS OF PREGNANCY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маринкин</surname><given-names>И. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Marinkin</surname><given-names>I. O.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соколова</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Sokolova</surname><given-names>T. M.</given-names></name></name-alternatives><email xlink:type="simple">tatyana3965@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Киселева</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kiseleva</surname><given-names>T. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кулешов</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuleshov</surname><given-names>V. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макаров</surname><given-names>К. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarov</surname><given-names>K. Yu.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Якимова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakimova</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО НГМУ МЗ РФ - Государственное бюджетное образовательное учреждение «Новосибирский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>SBEF HPE NSMU HMR - State Budget Educational Foundation of the High Professional Education «Novosibirsk State Medical University» of the Health Ministry of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>20</day><month>09</month><year>2016</year></pub-date><volume>0</volume><issue>9</issue><fpage>81</fpage><lpage>85</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Маринкин И.О., Соколова Т.М., Киселева Т.В., Кулешов В.М., Макаров К.Ю., Якимова А.В., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Маринкин И.О., Соколова Т.М., Киселева Т.В., Кулешов В.М., Макаров К.Ю., Якимова А.В.</copyright-holder><copyright-holder xml:lang="en">Marinkin I.O., Sokolova T.M., Kiseleva T.V., Kuleshov V.M., Makarov K.Y., Yakimova A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/286">https://www.nogr.org/jour/article/view/286</self-uri><abstract><p>В статье представлены данные о распространенности, клинике, методах диагностики, лечения и профилактике холестаза беременных, а также о тактике ведения пациенток в зависимости от срока беременности и тяжести течения холестаза. Представлен клинический пример типичного течения холестаза беременных.</p></abstract><trans-abstract xml:lang="en"><p>The article presents data concerning the prevalence, clinical manifestations, methods of diagnostics, treatment and prevention of cholestasis of pregnancy, as well as the case management depending on the gestation and the cholestasis severity. A clinical case of a typical course of cholestasis of pregnancy is presented</p></trans-abstract><kwd-group xml:lang="ru"><kwd>холестаз беременных</kwd><kwd>диагностика</kwd><kwd>лечение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cholestasis of pregnancy</kwd><kwd>diagnostics</kwd><kwd>treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Pusl Т., Beuers U. Intrahepatic cholestasis of pregnancy. Orphanet J. 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