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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-226-6-221-224</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-2823</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Необычное начало и течение болезни Крона у детей</article-title><trans-title-group xml:lang="en"><trans-title>Unusual onset and course of Crohn’s disease in children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8307-5168</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самолыго</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Samolygo</surname><given-names>I. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1951-6424</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аминова</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Aminova</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7659-1765</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ерюшова</surname><given-names>Т. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Yeryushova</surname><given-names>T. Yu.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0876-6548</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мацукатова</surname><given-names>Б. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Matsukatova</surname><given-names>B. O.</given-names></name></name-alternatives><email xlink:type="simple">matsukatova_b_o@staff.sechenov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-1802-4470</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андрианова</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Andrianova</surname><given-names>K. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-7144-371X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гундина</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gundina</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8689-7602</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Эрдес</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Erdes</surname><given-names>S. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый МГМУ им. И. М. Сеченова Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I. M. Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>22</day><month>10</month><year>2024</year></pub-date><volume>0</volume><issue>6</issue><fpage>221</fpage><lpage>224</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Самолыго И.С., Аминова А.И., Ерюшова Т.Ю., Мацукатова Б.О., Андрианова К.А., Гундина А.В., Эрдес С.И., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Самолыго И.С., Аминова А.И., Ерюшова Т.Ю., Мацукатова Б.О., Андрианова К.А., Гундина А.В., Эрдес С.И.</copyright-holder><copyright-holder xml:lang="en">Samolygo I.S., Aminova A.I., Yeryushova T.Y., Matsukatova B.O., Andrianova K.A., Gundina A.V., Erdes S.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/2823">https://www.nogr.org/jour/article/view/2823</self-uri><abstract><p>Цель: Демонстрация клинического случая болезни Крона у ребенка 8 лет. Материалы и методы: Приведенный клинический пример - это случай неклассического варианта течения болезни Крона у ребенка 8 лет, дебютировавшего с поражения верхних дыхательных путей в сочетании с болью в животе на фоне длительных курсов антибактериальной терапии. Заключение: Данный клинический случай демонстрирует сложность диагностического поиска, необходимость тщательного сбора анамнеза и проведения дифференциальной диагностики.</p></abstract><trans-abstract xml:lang="en"><p>The purpose of the article is to demonstrate a clinical case of Crohn’s disease in an 8-year-old child. Materials and methods: The given clinical example is a case of a non-classical variant of the course of Crohn’s disease in an 8-year-old child who debuted with an upper respiratory tract lesion in combination with abdominal pain against the background of long courses of antibacterial therapy. Conclusion: This clinical case demonstrates the complexity of the diagnostic search, the need for careful history collection and differential diagnosis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>клинический случай</kwd><kwd>болезнь Крона</kwd><kwd>ребенок</kwd><kwd>антибактериальная терапия</kwd><kwd>резистентность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>case report</kwd><kwd>Crohn’s disease</kwd><kwd>child</kwd><kwd>antibacterial therapy</kwd><kwd>resistance</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Yu Y. R., Rodriguez J. R. Clinical presentation of Crohn’s, ulcerative colitis, and indeterminate colitis: Symptoms, extraintestinal manifestations, and disease phenotypes. Semin Pediatr Surg. 2017;26(6):349-355. doi: 10.1053/j.sempedsurg.2017.10.003.</mixed-citation><mixed-citation xml:lang="en">Yu Y. R., Rodriguez J. R. Clinical presentation of Crohn’s, ulcerative colitis, and indeterminate colitis: Symptoms, extraintestinal manifestations, and disease phenotypes. Semin Pediatr Surg. 2017;26(6):349-355. doi: 10.1053/j.sempedsurg.2017.10.003.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Benchimol E. I., Fortinsky K. J., Gozdyra P. et al. Epidemiology of pediatric inflammatory bowel disease: a systematic review of international trends. Inflamm Bowel Dis. 2011;17(1):423-39. doi: 10.1002/ibd.21349.</mixed-citation><mixed-citation xml:lang="en">Benchimol E. I., Fortinsky K. J., Gozdyra P. et al. Epidemiology of pediatric inflammatory bowel disease: a systematic review of international trends. Inflamm Bowel Dis. 2011;17(1):423-39. doi: 10.1002/ibd.21349.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Pigneur B., Seksik P., Viola S. et al. Natural history of Crohn’s disease: comparison between childhood- and adult-onset disease. Inflamm Bowel Dis, 2010;16(6):953-61. doi: 10.1002/ibd.21152.</mixed-citation><mixed-citation xml:lang="en">Pigneur B., Seksik P., Viola S. et al. Natural history of Crohn’s disease: comparison between childhood- and adult-onset disease. Inflamm Bowel Dis, 2010;16(6):953-61. doi: 10.1002/ibd.21152.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Ruemmele F. M., Veres G., Kolho K. L. et al. European Crohn’s and Colitis Organisation; European Society of Pediatric Gastroenterology, Hepatology and Nutrition. Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn’s disease. J Crohns Colitis. 2014;8(10):1179-207. doi: 10.1016/j.crohns.2014.04.005.</mixed-citation><mixed-citation xml:lang="en">Ruemmele F. M., Veres G., Kolho K. L. et al. European Crohn’s and Colitis Organisation; European Society of Pediatric Gastroenterology, Hepatology and Nutrition. Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn’s disease. J Crohns Colitis. 2014;8(10):1179-207. doi: 10.1016/j.crohns.2014.04.005.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Plataki M., Tzortzaki E., Lambiri I. et al. Severe airway stenosis associated with Crohn’s disease: case report. BMC Pulm Med. 2006;7(6):7. doi: 10.1186/1471-2466-6-7.</mixed-citation><mixed-citation xml:lang="en">Plataki M., Tzortzaki E., Lambiri I. et al. Severe airway stenosis associated with Crohn’s disease: case report. BMC Pulm Med. 2006;7(6):7. doi: 10.1186/1471-2466-6-7.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Xia K., Wolf J., Friedman S., Carr-Locke D. L. Granulomatous tracheo-bronchitis associated with Crohn’s disease. MedGenMed. 2004;6(1):18.</mixed-citation><mixed-citation xml:lang="en">Xia K., Wolf J., Friedman S., Carr-Locke D. L. Granulomatous tracheo-bronchitis associated with Crohn’s disease. MedGenMed. 2004;6(1):18.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ruemmele F. M., Veres G., Kolho K. L. et al. European Crohn’s and Colitis Organisation; European Society of Pediatric Gastroenterology, Hepatology and Nutrition. Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn’s disease. J Crohns Colitis. 2014;8(10):1179-207. doi: 10.1016/j.crohns.2014.04.005.</mixed-citation><mixed-citation xml:lang="en">Ruemmele F. M., Veres G., Kolho K. L. et al. European Crohn’s and Colitis Organisation; European Society of Pediatric Gastroenterology, Hepatology and Nutrition. Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn’s disease. J Crohns Colitis. 2014;8(10):1179-207. doi: 10.1016/j.crohns.2014.04.005.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Feakins R. M. British Society of Gastroenterology. Inflammatory bowel disease biopsies: updated British Society of Gastroenterology reporting guidelines. J Clin Pathol. 2013;66(12):1005-26. doi: 10.1136/jclinpath-2013-201885.</mixed-citation><mixed-citation xml:lang="en">Feakins R. M. British Society of Gastroenterology. Inflammatory bowel disease biopsies: updated British Society of Gastroenterology reporting guidelines. J Clin Pathol. 2013;66(12):1005-26. doi: 10.1136/jclinpath-2013-201885.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Feakins R., Torres J., Borralho-Nunes P. et al. Differential Diagnosis of Inflammatory Bowel Disease. J Crohns Colitis. 2022;16(3):343-368. doi: 10.1093/ecco-jcc/jjab141.</mixed-citation><mixed-citation xml:lang="en">Feakins R., Torres J., Borralho-Nunes P. et al. Differential Diagnosis of Inflammatory Bowel Disease. J Crohns Colitis. 2022;16(3):343-368. doi: 10.1093/ecco-jcc/jjab141.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Theochari N. A., Stefanopoulos A., Mylonas K. S. Antibiotics exposure and risk of inflammatory bowel disease: a systematic review. Scand J Gastroenterol. 2018;53(1):1-7. doi: 1080/00365521.2017.1386711.</mixed-citation><mixed-citation xml:lang="en">Theochari N. A., Stefanopoulos A., Mylonas K. S. Antibiotics exposure and risk of inflammatory bowel disease: a systematic review. Scand J Gastroenterol. 2018;53(1):1-7. doi: 1080/00365521.2017.1386711.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Bernstein C. N. Review article: changes in the epidemiology of inflammatory bowel disease-clues for aetiology. Aliment Pharmacol Ther. 2017;46(10):911-919. doi: 10.1111/apt.14338.</mixed-citation><mixed-citation xml:lang="en">Bernstein C. N. Review article: changes in the epidemiology of inflammatory bowel disease-clues for aetiology. Aliment Pharmacol Ther. 2017;46(10):911-919. doi: 10.1111/apt.14338.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
