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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-226-6-194-204</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-2820</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEWS</subject></subj-group></article-categories><title-group><article-title>Недостаточность диаминоксидазы и ее роль в патогенезе заболеваний</article-title><trans-title-group xml:lang="en"><trans-title>Diamine oxidase deficiency and its role in the pathogenesis of diseases</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3606-4068</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шрайнер</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shrayner</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">sch704@icloud.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7308-7280</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хавкин</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Khavkin</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3522-5384</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Быстрова</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Bystrova</surname><given-names>V. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9048-7710</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лифшиц</surname><given-names>Г. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Lifshits</surname><given-names>G. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1173-7553</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Денисов</surname><given-names>М. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Denisov</surname><given-names>M. Yu.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Новосибирский государственный университет; Институт химической биологии и фундаментальной медицины СО РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State University; Institute of chemical, Institute of Chemical Biology and Fundamental Medicine of the SB RAS</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научно-исследовательский клинический институт детства Министерства здравоохранения Московской области; Федеральное Государственное Автономное Образовательное Учреждение Высшего Образования «Белгородский государственный национальный исследовательский университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Clinical Institute of Childhood, Ministry of Health of the Moscow Region; Belgorod State University (BelSU)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Новосибирский государственный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>22</day><month>10</month><year>2024</year></pub-date><volume>0</volume><issue>6</issue><fpage>194</fpage><lpage>204</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шрайнер Е.В., Хавкин А.И., Быстрова В.И., Лифшиц Г.И., Денисов М.Ю., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Шрайнер Е.В., Хавкин А.И., Быстрова В.И., Лифшиц Г.И., Денисов М.Ю.</copyright-holder><copyright-holder xml:lang="en">Shrayner E.V., Khavkin A.I., Bystrova V.I., Lifshits G.I., Denisov M.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/2820">https://www.nogr.org/jour/article/view/2820</self-uri><abstract><p>Непереносимость гистамина - гистаминоз, представляет собой расстройство, связанное с нарушением способности усваивать поступающий внутрь гистамин. Гистаминоз встречается у 1-3% населения. Данное состояние было описано в начале 21-го века. В этой статье представлен обзор непереносимости гистамина, в основном посвященный клиническим проявлениям, диагностике и лечению.</p></abstract><trans-abstract xml:lang="en"><p>Histamine intolerance is a disorder associated with impaired ability to absorb ingested histamine. Histaminosis occurs in 1-3% of the population. This condition was described at the beginning of the 21st century. This article provides an overview of histamine intolerance, mainly devoted to clinical manifestations, diagnosis and treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>непереносимость гистамина</kwd><kwd>диаминоксидаза</kwd><kwd>гистамин</kwd><kwd>гистаминоз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>histamine intolerance</kwd><kwd>diamine oxidase</kwd><kwd>histamine</kwd><kwd>histaminosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Comas-Basté O, Sánchez-Pérez S, Veciana-Nogués MT, Latorre-Moratalla M, Vidal-Carou MDC. Histamine Intolerance: The Current State of the Art. Biomolecules. 2020;10(8):1181. doi: 10.3390/biom10081181</mixed-citation><mixed-citation xml:lang="en">Comas-Basté O, Sánchez-Pérez S, Veciana-Nogués MT, Latorre-Moratalla M, Vidal-Carou MDC. Histamine Intolerance: The Current State of the Art. 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Клиническое значение изучения генетического полиморфизма факторов адгезии при Helicobacter pylori-ассоциированных заболеваниях. Экспериментальная и клиническая гастроэнтерология. 2022;(1):18-23. doi: 10.31146/1682-8658-ecg-197-1-18-23.</mixed-citation><mixed-citation xml:lang="en">Lifshits G. I., Shrayner E. V., Kokh N. V., Voronina E. N., Khavkin A. I. Clinical significance of studying the genetic polymorphism of adhesion factors in Helicobacter pylori-associated diseases. Experimental and Clinical Gastroenterology. 2022;(1):18-23. (In Russ.) doi: 10.31146/1682-8658-ecg-197-1-18-23.@@ Лифшиц Г. И., Шрайнер Е. В., Кох Н. В., Воронина Е. Н., Хавкин А. И. Клиническое значение изучения генетического полиморфизма факторов адгезии при Helicobacter pylori-ассоциированных заболеваниях. 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