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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-226-6-101-108</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-2806</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Ожирение матери как риск коморбидности у детей</article-title><trans-title-group xml:lang="en"><trans-title>Maternal obesity as a risk of comorbidity in children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5412-1412</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прокопьева</surname><given-names>Н. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Prokopyeva</surname><given-names>N. E.</given-names></name></name-alternatives><email xlink:type="simple">shkunat93@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0060-4168</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванов</surname><given-names>Д. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanov</surname><given-names>D. O.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8623-4574</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петренко</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrenko</surname><given-names>Yu. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0992-1709</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новикова</surname><given-names>В. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Novikova</surname><given-names>V. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Санкт-Петербургский государственный педиатрический медицинский университет» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St. Petersburg State Pediatric Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>22</day><month>10</month><year>2024</year></pub-date><volume>0</volume><issue>6</issue><fpage>101</fpage><lpage>108</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Прокопьева Н.Э., Иванов Д.О., Петренко Ю.В., Новикова В.П., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Прокопьева Н.Э., Иванов Д.О., Петренко Ю.В., Новикова В.П.</copyright-holder><copyright-holder xml:lang="en">Prokopyeva N.E., Ivanov D.O., Petrenko Y.V., Novikova V.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/2806">https://www.nogr.org/jour/article/view/2806</self-uri><abstract><p>Цель. Изучить влияние материнского ожирения на состояние здоровья детей в первый год жизни. Материалы и методы. В исследование включено 90 детей: 1 группа - 54 ребенка от матерей с ожирением (индекс массы тела матери до беременности ≥ 30 кг/м2); 2 группа - 36 детей от матерей с нормальным индексом массы тела (18,5-24,9 кг/м2). Всем детям проводилась оценка течения перинатального периода и состояния здоровья в течение первого года жизни при динамическом наблюдении. Результаты исследования. Выявлено, что новорожденные от матерей с ожирением значимо чаще имели массу тела более 4000 граммов (20,4% и 10,6%, р = 0,026). Перинатальный период в этой группе детей чаще сопровождался асфиксией новорожденных (11,0% и 1,6%; р = 0,003), требующей искусственной вентиляции легких (10,2%, и 1,6%; р = 0,003) и терапии в условиях отделения реанимации и интенсивной терапии (10,9% и 1,6%; р = 0,002). При динамическом наблюдении отмечено, что у детей от матерей с ожирением чаще встречались аномалии развития мочевыделительной системы (40,7% и 25,0%, р = 0,03). Эти дети статистически значимо чаще болели острыми респираторными вирусными инфекциями (32,1% и 19,4%, р = 0,03), острыми кишечными инфекциями (24,1% и 11,1%, р = 0,02) и инфекциями мочевыводящих путей (20,4% и 11,1%, р = 0,04). У них с большей частотой диагностировались: анемия легкой степени тяжести (24,1% и 8,3%, р = 0,03) и атопический дерматит (38,9% и 25,0%, р = 0,02). Заключение. Полученные результаты демонстрируют значимое влияние материнского ожирения в развитии неблагоприятных исходов у потомства, таких как: нарушений постнатальной адаптации, асфиксии, увеличение частоты аномалий развития и заболеваемости у детей в течение первого года жизни, а также указывают на риски развития коморбидных состояний у детей в будущем.</p></abstract><trans-abstract xml:lang="en"><p>Aim. To study the impact of maternal obesity on children’s health in the first year of life. Materials and methods. The study included 90 children: group 1-54 children from obese mothers (maternal body mass index before pregnancy ≥ 30 kg/m2); Group 2-36 children from mothers with a normal body mass index (18.5-24.9 kg/m2). All children were assessed for the course of the perinatal period and health status during the first year of life during dynamic observation. Research results. It was found that newborns from obese mothers were significantly more likely to have a body weight of more than 4000 grams (20.4% and 10.6%, p = 0.026). The perinatal period in this group of children was more often accompanied by asphyxia of newborns (11.0% and 1.6%; p = 0.003), requiring artificial ventilation (10.2% and 1.6%; p = 0.003) and therapy in conditions intensive care units (10.9% and 1.6%; p = 0.002). During dynamic observation, it was noted that in children from obese mothers, anomalies in the development of the urinary system were more common (40.7% and 25.0%, p = 0.03). These children were statistically significantly more likely to suffer from acute respiratory viral infections (32.1% and 19.4%, p = 0.03), acute intestinal infections (24.1% and 11.1%, p = 0.02) and urinary tract (20.4% and 11.1%, p = 0.04). They were diagnosed with a higher frequency of mild anemia (24.1% and 8.3%, p = 0.03) and atopic dermatitis (38.9% and 25.0%, p = 0.02). Conclusion. The results obtained demonstrate the significant influence of maternal obesity in the development of adverse perinatal outcomes, such as: disorders of postnatal adaptation, asphyxia, an increase in the frequency of developmental anomalies and morbidity in children during the first year of life and indicate the risks of developing comorbid conditions in children in the future.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>материнское ожирение</kwd><kwd>перинатальный период</kwd><kwd>коморбидные состояния</kwd></kwd-group><kwd-group xml:lang="en"><kwd>maternal obesity</kwd><kwd>perinatal period</kwd><kwd>comorbid conditions</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bezrukova D. A., Dzhumagaziev A. A., Otto N.Yu. et al. Early and late effects of maternal obesity in the mother-child dyad. Issues of pediatric dietology. 2021; 19(4): 46-55. 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