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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nogr-267</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>СОЧЕТАНИЕ ЦЕЛИАКИИ И ПСОРИАЗА У 5-ЛЕТНЕГО РЕБЕНКА</article-title><trans-title-group xml:lang="en"><trans-title>COELIAC DISEASE AND PSORIASIS COMBINATION IN 5-YEAR-OLD CHILD</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Комарова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Komarova</surname><given-names>O. N.</given-names></name></name-alternatives><email xlink:type="simple">komarova@pedklin.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хавкин</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Khavkin</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>РНИМУ им. Н. И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>20</day><month>08</month><year>2016</year></pub-date><volume>0</volume><issue>8</issue><fpage>98</fpage><lpage>103</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Комарова О.Н., Хавкин А.И., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Комарова О.Н., Хавкин А.И.</copyright-holder><copyright-holder xml:lang="en">Komarova O.N., Khavkin A.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/267">https://www.nogr.org/jour/article/view/267</self-uri><abstract><p>В статье демонстрируется клинический случай ребенка, наблюдаемого в течение 3-х лет, родители которого изначально обратились с жалобами на незаживающие трещины между пальцами ног, в области пупка, вульвы и за ушами при назначении традиционной терапии. Ребенку по месту жительства проведено полное аллергологическое обследование, результаты которого были нормативными. Неэффективная терапия заболевания кожи, а также наличие отягощенной наследственности по аутоиммунным заболеваниям послужили необходимостью госпитализации пациента для проведения обследования. При обследовании в клинике выявлены высокие значения антител к тканевой трансглутаминазе и глиадину в крови, дуоденоеюнит по данным еюноскопии и проявления хронического активного выраженного энтерита с тотальной атрофией ворсин на протяженном участке слизистой оболочки тонкой кишки по результатам морфологического исследования биоптатов. На основании полученных результатов поставлен диагноз целиакия. На фоне безглютеновой диеты отмечалась нормализация лабораторных и морфологических показателей. Клинически - весо-ростовых показателей, результатов денситометрии, однако, было лишь незначительное улучшение со стороны поражения кожи. При повторном обследовании ребенку поставлен сопутствующий диагноз псориаз.</p></abstract><trans-abstract xml:lang="en"><p>The article demonstrates a clinical case of a child observed over 3 years, whose parents initially complained of non-healing crack between the toes, the navel, the vulva and behind the ears in the appointment of traditional therapy. The child in the community conducted a full survey of allergy, the results of which were normative. Ineffective treatment of skin diseases, as well as the presence of family history for autoimmune diseases served as the need for hospitalization of the patient survey. The examination at the clinic revealed higher values of antibodies to tissue transglutaminase and gliadin in the blood, duodenojejunal according to the results of endoscopy and active manifestations of chronic enteritis expressed with total villous atrophy on the long section on the results of morphological study of biopsies of the small intestine mucosa. Based on the results diagnosis of coeliac disease. On the background of a gluten-free diet showed normalization of laboratory and morphological parameters, weight and growth rates, the results of densitometry. However, it was only a slight improvement from the skin lesions. When re-examination of the child set accompanying diagnosis of psoriasis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>целиакия</kwd><kwd>псориаз</kwd><kwd>аутоиммунные заболевания</kwd><kwd>безглютеновая диета</kwd></kwd-group><kwd-group xml:lang="en"><kwd>coeliac disease</kwd><kwd>psoriasis</kwd><kwd>autoimmune diseases</kwd><kwd>gluten free diet</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бишарова А. С. Псориаз у детей. Лечащий врач. 2006; 9:34-37.</mixed-citation><mixed-citation xml:lang="en">Бишарова А. С. Псориаз у детей. 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