nogrЭкспериментальная и клиническая гастроэнтерологияExperimental and Clinical Gastroenterology1682-8658«Global Media Technologies»10.31146/1682-8658-ecg-219-11-120-129nogr-2607Research ArticleСтатьиАккомодация желудка: патогенетическая роль и клиническое значениеGastric accommodation: pathogenetic role and clinical significancehttps://orcid.org/0000-0003-4479-508XШкляевА. Е.ShklyaevA. E.shklyaevaleksey@gmail.comФедеральное государственное бюджетное образовательное учреждение высшего образования «Ижевская государственная медицинская академия» Министерства здравоохранения Российской ФедерацииРоссияIzhevsk State Medical AcademyRussian Federation202326032024011120129Copyright © Шкляев А.Е., 20242024Шкляев А.Е.Shklyaev A.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.nogr.org/jour/article/view/2607

В статье представлен литературный обзор современных российских и зарубежных публикаций, посвященных изучению аккомодации желудка. Показано, что аккомодация проксимального отдела желудка играет важную роль в его адаптации к приему пищи. Данный процесс осуществляется в две стадии при участии парасимпатической и паракринной регуляции, важную роль также играют эффекты нутриентов при попадании их в двенадцатиперстную кишку. К методам оценки аккомодации желудка относят желудочный баростат, сцинтиграфию желудка с пищевой нагрузкой, питьевые тесты, однофотонную эмиссионную компьютерную томографию, магнитно-резонансную томографию и ультразвуковое исследование желудка, внутрижелудочную манометрию. Нарушение аккомодации желудка приводит к избыточному повышению внутрижелудочного давления и возникновению симптомов, наиболее часто встречающихся при функциональной диспепсии, гастроэзофагеальной рефлюксной болезни и диабетической гастропатии. Подходы к лечению нарушений аккомодации желудка находятся на стадии разработки, обсуждаются возможности диетотерапии, фармакологической и немедикаментозной коррекции.

The article presents a literature review of modern Russian and foreign publications devoted to the study of gastric accommodation. It has been shown that accommodation of the proximal stomach plays an important role in its adaptation to food intake. This process is carried out in two stages with the participation of parasympathetic and paracrine regulation; the effects of nutrients when they enter the duodenum also play an important role. Methods for assessing gastric accommodation include gastric barostat, gastric scintigraphy with food load, drinking tests, single-photon emission computed tomography, magnetic resonance imaging and ultrasound examination of the stomach, intragastric manometry. Violation of gastric accommodation leads to an excessive increase in intragastric pressure and the occurrence of symptoms most often found in functional dyspepsia, gastroesophageal reflux disease and diabetic gastropathy. Approaches to the treatment of gastric accommodation disorders are at the development stage, the possibilities of diet therapy, pharmacological and non-drug correction are being discussed.

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The authors declare that there are no conflicts of interest present.