nogrЭкспериментальная и клиническая гастроэнтерологияExperimental and Clinical Gastroenterology1682-8658«Global Media Technologies»10.31146/1682-8658-ecg-219-11-112-119nogr-2606Research ArticleОБЗОРREVIEWСовременные аспекты вагус-индуцированной гастропротекции и ульцерогенеза при язвенной болезни желудка и двенадцатиперстной кишкиModern aspects of vagus-induced gastroprotection and ulcerogenesis in gastric and duodenal ulcershttps://orcid.org/0000-0003-0632-6653ЮсуповФ. А.YusupovF. A.noemail@neicon.ruhttps://orcid.org/0000-0002-4179-9205ЮлдашевА. А.YuldashevA. A.akmal.yuldashev.2017@list.ruОшский государственный университетРоссияOsh State UniversityRussian Federation202326032024011112119Copyright © Юсупов Ф.А., Юлдашев А.А., 20242024Юсупов Ф.А., Юлдашев А.А.Yusupov F.A., Yuldashev A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.nogr.org/jour/article/view/2606

Блуждающий нерв является незаменимым соединением между телом и мозгом, которое контролирует жизненно важные аспекты вегетативной физиологии, такие как дыхание, частота сердечных сокращений, кровяное давление и перистальтика кишечника, рефлексы, такие как кашель и глотание, а также поведение, связанное с выживанием, такое как прием пищи, питье и реакция на тошноту. Желудок имеет сложный нервный аппарат. Иннервация желудка обеспечивается как соматической, так и вегетативной нервной системой. Желудок получает иннервация от блуждающего нерва и производные чревного сплетения (верхнее брыжеечное, желудочное, селезеночные, печеночные). Наибольшую влияние на работу желудка и кишечника оказывает блуждающий нерв. Блуждающий нерв самый длинный внутренностный нерв буквально блуждает по всему телу. Блуждающие нервы играют доминирующую роль в стимуляции желудочной секреции. Базальная или непрерывная секреция желудочного сока в норме у человека полностью обусловлена тоническими импульсами в блуждающих нервах. Целью нашего обзора явилось выявление патогенетической роли блуждающего нерва при язвенной болезни желудка и двенадцатиперстной кишки.

The vagus nerve is an essential connection between the body and the brain that controls vital aspects of autonomic physiology such as respiration, heart rate, blood pressure and intestinal motility, reflexes such as coughing and swallowing, and survival behaviors such as eating, drinking and response to nausea. The stomach has a complex nervous apparatus. The innervation of the stomach is provided by both the somatic and the autonomic nervous system. The stomach receives innervation from the vagus nerve and derivatives of the celiac plexus (superior mesenteric, gastric, splenic, hepatic). The vagus nerve has the greatest influence on the work of the stomach and intestines. The vagus nerve is the longest splanchnic nerve, literally wandering throughout the body. The vagus nerves play a dominant role in stimulating gastric secretion. The basal or continuous secretion of gastric juice in normal humans is entirely due to tonic impulses in the vagus nerves. The purpose of our review was to identify the pathogenetic role of the vagus nerve in gastric and duodenal ulcers.

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The authors declare that there are no conflicts of interest present.