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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-211-3-161-167</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-2349</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Комплексный эндоскопический подход в лечении пациентки с аденомой большого сосочка двенадцатиперстной кишки, холедохолитиазом и стриктурой терминального отдела общего желчного протока</article-title><trans-title-group xml:lang="en"><trans-title>Intraluminal endoscopic complex approach in the treatment of a patient with adenoma of the major duodenal papilla, choledocholithiasis and stricture of the terminal common bile duct</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4722-3466</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Старков</surname><given-names>Ю. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Starkov</surname><given-names>Yu. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0773-0498</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вагапов</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Vagapov</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">vagapov9494@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2515-9942</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Замолодчиков</surname><given-names>Р. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Zamolodchikov</surname><given-names>R. D.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8657-8609</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джантуханова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzhantukhanova</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4274-9362</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ибрагимов</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ibragimov</surname><given-names>A. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр хирургии им. А. В. Вишневского» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Vishnevsky National Medical Research Center of Surgery</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>25</day><month>07</month><year>2023</year></pub-date><volume>0</volume><issue>3</issue><fpage>161</fpage><lpage>167</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Старков Ю.Г., Вагапов А.И., Замолодчиков Р.Д., Джантуханова С.В., Ибрагимов А.С., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Старков Ю.Г., Вагапов А.И., Замолодчиков Р.Д., Джантуханова С.В., Ибрагимов А.С.</copyright-holder><copyright-holder xml:lang="en">Starkov Y.G., Vagapov A.I., Zamolodchikov R.D., Dzhantukhanova S.V., Ibragimov A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/2349">https://www.nogr.org/jour/article/view/2349</self-uri><abstract><p>Введение. Аденомы большого сосочка двенадцатиперстной кишки - это доброкачественные новообразования, но из-за высокой частоты малигнизации они подлежат удалению. В настоящее время в качестве альтернативы хирургическим методам вмешательств все чаще рассматриваются минимально инвазивные методы операций, при этом особую сложность в эндоскопическом лечении представляют случаи сочетания новообразования большого сосочка двенадцатиперстной кишки с холедохолитиазом и стриктурами желчного протока. Клиническое наблюдение. Пациентка 62 лет проходила комплексное эндоскопическое лечение в НМИЦ хирургии им. А. В. Вишневского по поводу аденомы большого сосочка двенадцатиперстной кишки IV типа, распространяющейся на стенки двенадцатиперстной кишки и терминальный отдел общего желчного протока, в сочетании с холедохолитиазом и рубцовой стриктурой общего желчного протока. Обсуждение. В лечении пациентки успешно применен комплексный подход минимально инвазивного лечения в объеме эндоскопической литоэкстракции, пофрагментного удаления аденомы большого сосочка двенадцатиперстной кишки с внутрипротоковой высокочастотной электрохирургической абляцией резидуальной аденоматозной ткани и последующими этапными билиарными стентированиями по поводу рубцовой стриктуры общего желчного протока, а также стентированием главного панкреатического протока для профилактики постманипуляционного панкреатита. Заключение. Комплексный подход в лечении пациентки аденомой большого сосочка двенадцатиперстной кишки IV типа, холедохолитиазом и стриктурой общего желчного протока, позволил добиться клинического успеха при отсутствии осложнений и необходимости в длительной реабилитации.</p></abstract><trans-abstract xml:lang="en"><p>Introduction. Adenomas of the major duodenal papilla are benign neoplasms, but due to their high tendency to malignancy, they must be removed. At present, minimally invasive methods of operations are increasingly being considered as an alternative to surgical interventions, while cases of a combination of a neoplasm of the major duodenal papilla with choledocholithiasis and bile duct strictures are of particular difficulty in endoscopic treatment. Clinical case. A 62-year-old patient underwent complex endoscopic treatment at the Vishnevsky National Research Medical Center for Surgery about adenoma of the major duodenal papilla type IV, extending to the walls of the duodenum and the terminal section of the common bile duct, in combination with choledocholithiasis and cicatricial stricture of the common bile duct. Results. The patient successfully applied a complex approach of minimally invasive treatment in the amount of endoscopic lithoextraction, fragmentary removal of adenoma of the major duodenal papilla with intraductal high-frequency electrosurgical ablation of residual adenomatous tissue and subsequent staged biliary stenting for cicatricial stricture of the common bile duct, as well as stenting of the main pancreatic duct to prevent post-manipulation pancreatitis. Discussion. An integrated approach in the treatment of a patient with adenoma of the major duodenal papilla IV, choledocholithiasis and stricture of the common bile duct, made it possible to achieve clinical success in the absence of complications and the need for long-term rehabilitation.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Аденома большого сосочка двенадцатиперстной кишки</kwd><kwd>стентирование</kwd><kwd>рубцовая стриктура</kwd><kwd>холедохолитиаз</kwd><kwd>эндоскопическое лечение</kwd><kwd>высокочастотная электрохирургическая абляция резидуальной внутрипротоковой аденомы</kwd><kwd>эндоскопическая классификация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Adenoma of the major duodenal papilla</kwd><kwd>stenting</kwd><kwd>cicatricial stricture</kwd><kwd>choledocholithiasis</kwd><kwd>endoscopic treatment</kwd><kwd>high-frequency electrosurgical ablation of residual intra-flow adenoma</kwd><kwd>endoscopic classification</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Panzeri F., Crippa S, Castelli P., Aleotti F., Pucci A., Partelli S., Zamboni G., Falconi M. 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