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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-211-3-156-160</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-2348</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Клинический случай вируса папилломы человека (ВПЧ) и кондилома Бушке-Левенштейна</article-title><trans-title-group xml:lang="en"><trans-title>Clinical case of giant buschke-levenstein condyloma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0440-7118</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Надей</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nadey</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">nadeyelena@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4878-0838</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лялюкова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyalyukova</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6134-1533</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Усачева</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Usacheva</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Набока</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Naboka</surname><given-names>M. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Омский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>25</day><month>07</month><year>2023</year></pub-date><volume>0</volume><issue>3</issue><fpage>156</fpage><lpage>160</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Надей Е.В., Лялюкова Е.А., Усачева Е.В., Набока М.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Надей Е.В., Лялюкова Е.А., Усачева Е.В., Набока М.В.</copyright-holder><copyright-holder xml:lang="en">Nadey E.V., Lyalyukova E.A., Usacheva E.V., Naboka M.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/2348">https://www.nogr.org/jour/article/view/2348</self-uri><abstract><p>В статье описывается клинический случай вируса папилломы человека (ВПЧ) и кондиломы Бушке - Левенштейна. Развитие опухоли связывают с папилломавирусной инфекцией на фоне иммунодефицитного состояния. Рассматриваются трудности выявления причинно-значимого фактора, сложности ведения пациента, риск неблагоприятного исхода заболевания. Данный клинический пример демонстрирует необходимость проведения своевременного обследования мужчин на папилломавирусную инфекцию и поиск новых методов терапии на фоне топических и системных иммуностимуляторов.</p></abstract><trans-abstract xml:lang="en"><p>The article describes a clinical case of Buschke - Levenstein condyloma. The development of the tumor is associated with a papillomavirus infection against the background of an immunodeficiency condition. The difficulties of identifying a causally significant factor, the complexity of patient management, the risk of an unfavorable outcome of the disease are considered. This clinical example demonstrates the need for a timely examination of men for papillomavirus infection and the search for new therapies against the background of topical and systemic immunostimulants.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>вирус</kwd><kwd>инфекция</kwd><kwd>опухоль</kwd><kwd>кандилома</kwd><kwd>иммунитет</kwd></kwd-group><kwd-group xml:lang="en"><kwd>virus</kwd><kwd>infection</kwd><kwd>tumor</kwd><kwd>candyloma</kwd><kwd>immunity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rogovskaya S.I. [The prevalence of human papillomavirus infection in Russia]. Epidemiology and vaccine prevention. 2012, No. 1, pp. 25-33. (in Russ.)@@ Роговская С. И. Распространенность папилломавирусной инфекции в России. Эпидемиология и вакцинопрофилактика. 2012. № 1. С. 25-33.</mixed-citation><mixed-citation xml:lang="en">Rogovskaya S.I. 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