<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-211-3-144-147</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-2346</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Новые возможности лечебного питания у больных с подагрой</article-title><trans-title-group xml:lang="en"><trans-title>New possibilities of therapeutic nutrition in patients with gout</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2363-5215</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рустамова</surname><given-names>М. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Rustamova</surname><given-names>M. T.</given-names></name></name-alternatives><email xlink:type="simple">mamlakatrustamova2018@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хайруллаева</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Khairullaeva</surname><given-names>S. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сарыбаева</surname><given-names>Г. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Sarybaeva</surname><given-names>G. K.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хайтимбетов</surname><given-names>Ж. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Khaitimbetov</surname><given-names>Z. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ташкентская медицинская академия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tashkent Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>25</day><month>07</month><year>2023</year></pub-date><volume>0</volume><issue>3</issue><fpage>144</fpage><lpage>147</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Рустамова М.Т., Хайруллаева С.С., Сарыбаева Г.К., Хайтимбетов Ж.Ш., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Рустамова М.Т., Хайруллаева С.С., Сарыбаева Г.К., Хайтимбетов Ж.Ш.</copyright-holder><copyright-holder xml:lang="en">Rustamova M.T., Khairullaeva S.S., Sarybaeva G.K., Khaitimbetov Z.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/2346">https://www.nogr.org/jour/article/view/2346</self-uri><abstract><p>Подагра, одна из наиболее распространенных форм воспалительного артрита. Известно, что подагра возникает в связи с депонированием кристаллов моно-урата натрия в суставах из-за высокого уровня сывороточной мочевой кислоты. Одним из главных факторов риска развития подагры считается особенности питания. Изменения пищевых привычек и рекомендации по модификации образа жизни при подагре являются основными принципами лечения и ведения пациентов. Целью данного исследования является обобщение текущих знаний по немедикаментозному лечению и ведению пациентов с подагрой.</p></abstract><trans-abstract xml:lang="en"><p>Gout is one of the most common forms of inflammatory arthritis. It is known that gout occurs in connection with the deposition of mono-sodium urate crystals in the joints due to high levels of serum uric acid. One of the main risk factors for developing gout is dietary habits. Changes in dietary habits and recommendations for lifestyle modification in gout are the main principles of treatment and management of patients. The purpose of this study is to summarize the current knowledge on non-pharmacological treatment and management of patients with gout.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>подагра</kwd><kwd>диета</kwd><kwd>образ жизни</kwd><kwd>лечебное питание</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gout</kwd><kwd>diet</kwd><kwd>lifestyle</kwd><kwd>clinical nutrition</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Zhu Y, Pandya BJ, Choi HK. Prevalence of gout and hyperuricemia in the US general population: the National Health and Nutrition Examination Survey 2007-2008. ArthritisRheum. 2011;63(10):3136-41. doi: 10.1002/art.30520.</mixed-citation><mixed-citation xml:lang="en">Zhu Y, Pandya BJ, Choi HK. Prevalence of gout and hyperuricemia in the US general population: the National Health and Nutrition Examination Survey 2007-2008. ArthritisRheum. 2011;63(10):3136-41. doi: 10.1002/art.30520.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Gromova M.A., Tsurko V. V., Melekhina A. S. Rational approach to nutrition for patients with gout. The Clinician. 2019;13(3-4):15-21. (In Russ.) doi: 10.17650/1818-8338-2019-13-3-4-15-21.@@ Громова М. А., Цурко В. В., Мелехина А. С. Рационально-обоснованный подход к питанию у больных подагрой. Клиницист. 2019; 13(3-4):15-21. doi: 10.17650/1818-8338-2019-13-3-4-15-21.</mixed-citation><mixed-citation xml:lang="en">Gromova M.A., Tsurko V. V., Melekhina A. S. Rational approach to nutrition for patients with gout. The Clinician. 2019;13(3-4):15-21. (In Russ.) doi: 10.17650/1818-8338-2019-13-3-4-15-21.@@ Громова М. А., Цурко В. В., Мелехина А. С. Рационально-обоснованный подход к питанию у больных подагрой. Клиницист. 2019; 13(3-4):15-21. doi: 10.17650/1818-8338-2019-13-3-4-15-21.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Mirakhmedova Kh.T. [National clinical position on the management of patients with gout]. Tashkent, 2021. 15P. (in Russ.)@@ Мирахмедова Х. Т. (ред.). Национальное клиническое положение по ведению больных подагрой. Ташкент, 2021. 15с.</mixed-citation><mixed-citation xml:lang="en">Mirakhmedova Kh.T. [National clinical position on the management of patients with gout]. Tashkent, 2021. 15P. (in Russ.)@@ Мирахмедова Х. Т. (ред.). Национальное клиническое положение по ведению больных подагрой. Ташкент, 2021. 15с.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Association of rheumatologists of Russia. Gout. Clinical guidelines. 2018. (in Russ.) Available at: URL: http://cr.rosminzdrav.ru/#!/recomend/174 (access date: 01.20.2021) @@ Ассоциация ревматологов России. Подагра. Клинические рекомен-дации. 2018. (Электронный ресурс.) URL: http://cr.rosminzdrav.ru/#!/ recomend/174(дата обращения: 20.01.2021).</mixed-citation><mixed-citation xml:lang="en">Association of rheumatologists of Russia. Gout. Clinical guidelines. 2018. (in Russ.) Available at: URL: http://cr.rosminzdrav.ru/#!/recomend/174 (access date: 01.20.2021) @@ Ассоциация ревматологов России. Подагра. Клинические рекомен-дации. 2018. (Электронный ресурс.) URL: http://cr.rosminzdrav.ru/#!/ recomend/174(дата обращения: 20.01.2021).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">FitzGerald J.D., Dalbeth N., Mikuls T., Brignardello-Petersen R., Guyatt G., Abeles A. M. et al. 2020 American College of Rheumatology Guideline for the Management of Gout. Arthritis Care &amp; Researches (Hoboken). 2020;72(6): 744-761.</mixed-citation><mixed-citation xml:lang="en">FitzGerald J.D., Dalbeth N., Mikuls T., Brignardello-Petersen R., Guyatt G., Abeles A. M. et al. 2020 American College of Rheumatology Guideline for the Management of Gout. Arthritis Care &amp; Researches (Hoboken). 2020;72(6): 744-761.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Nasonov E. L.Russian clinical guidelines. Rheumatology. Moscow. GEOTAR-Media, 2017. 464 p. (in Russ.)@@ Насонов Е. Л. (ред.). Российские клинические рекомендации. Ревматология. Мoscow. ГЭОТАР-Медиа; 2017. 464 с.</mixed-citation><mixed-citation xml:lang="en">Nasonov E. L.Russian clinical guidelines. Rheumatology. Moscow. GEOTAR-Media, 2017. 464 p. (in Russ.)@@ Насонов Е. Л. (ред.). Российские клинические рекомендации. Ревматология. Мoscow. ГЭОТАР-Медиа; 2017. 464 с.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Nabieva D. A. The relationship of hireruricemia and hyperlipidemia in men with primary gout. Scientific journal young science «Juvenis scienta» St. Petersburg. 2016, No. 1, pp.27-29. (in Russ.)@@ Набиева Д. А. Взаимосвязи гирерурикемии и гиперлипидемии у мужчин первичной подагрой. Научный журнал молодая наука «Juvenis scienta» Санкт-Петербург. 2016, № 1. С. 27-29.</mixed-citation><mixed-citation xml:lang="en">Nabieva D. A. The relationship of hireruricemia and hyperlipidemia in men with primary gout. Scientific journal young science «Juvenis scienta» St. Petersburg. 2016, No. 1, pp.27-29. (in Russ.)@@ Набиева Д. А. Взаимосвязи гирерурикемии и гиперлипидемии у мужчин первичной подагрой. Научный журнал молодая наука «Juvenis scienta» Санкт-Петербург. 2016, № 1. С. 27-29.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Tsurko V. V., Gromova M. A. A rationally grounded approach to treating gout with regard to its onset and course and the presence of comorbidity according to the European League against Rheumatism (EULAR 2016) recommendations. Therapeutic archive. 2017; 89(12):233-237. (in Russ.) doi: 10.17116/terarkh20178912233-237.@@ Цурко В. В., Громова М. А. Рационально-обоснованный подход к лечению подагры с учетом дебюта, течения и сочетанной патологии по материалам рекомендаций Европейской антиревматической лиги (EULAR 2016). Терапевтический архив. 2017; 89(12):233-237. doi: 10.17116/terarkh20178912233-237.</mixed-citation><mixed-citation xml:lang="en">Tsurko V. V., Gromova M. A. A rationally grounded approach to treating gout with regard to its onset and course and the presence of comorbidity according to the European League against Rheumatism (EULAR 2016) recommendations. Therapeutic archive. 2017; 89(12):233-237. (in Russ.) doi: 10.17116/terarkh20178912233-237.@@ Цурко В. В., Громова М. А. Рационально-обоснованный подход к лечению подагры с учетом дебюта, течения и сочетанной патологии по материалам рекомендаций Европейской антиревматической лиги (EULAR 2016). Терапевтический архив. 2017; 89(12):233-237. doi: 10.17116/terarkh20178912233-237.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Khanna D., Fitzgerald J. D., Khanna P. P., Bae S., Singh M. K., Neogi T. et al. 2012 American College of Rheumatology guidelines for management of gout. Part 1: Systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia. Arthritis Care &amp; Researches (Hoboken). 2012; 64:1431-1446. doi: 10.1002/acr.21772.</mixed-citation><mixed-citation xml:lang="en">Khanna D., Fitzgerald J. D., Khanna P. P., Bae S., Singh M. K., Neogi T. et al. 2012 American College of Rheumatology guidelines for management of gout. Part 1: Systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia. Arthritis Care &amp; Researches (Hoboken). 2012; 64:1431-1446. doi: 10.1002/acr.21772.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Roddy E., Doherty M. Epidemiology of gout. Arthritis Res Ther. 2010;12 (6):223. (in Russ.) doi: 10.1186/ar3199</mixed-citation><mixed-citation xml:lang="en">Roddy E., Doherty M. Epidemiology of gout. Arthritis Res Ther. 2010;12 (6):223. (in Russ.) doi: 10.1186/ar3199</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Rizamukhamedova M.Z., Nabieva D. A., Kurbanova Sh.R. [Diagnostic and therapeutic significance of the principles of diagnosis and treatment of patients with gout according to Ibn Sina]. [Teachings of Ibn Sina in the development of science. 7- International Ibn Sin readings]. Bukhara, 2013, p.83. (in Russ.) @@ Ризамухамедова М. З., Набиева Д. А., Курбанова Ш. Р. Диагностичес-кое и терапевтическое значение принципов диагностики и лечения больных подагрой по Ибн Сине. Учение Ибн Сины в развитии науки. 7- Международные Ибн Синские чтения. Бухара, 2013, С. 83.</mixed-citation><mixed-citation xml:lang="en">Rizamukhamedova M.Z., Nabieva D. A., Kurbanova Sh.R. [Diagnostic and therapeutic significance of the principles of diagnosis and treatment of patients with gout according to Ibn Sina]. [Teachings of Ibn Sina in the development of science. 7- International Ibn Sin readings]. Bukhara, 2013, p.83. (in Russ.) @@ Ризамухамедова М. З., Набиева Д. А., Курбанова Ш. Р. Диагностичес-кое и терапевтическое значение принципов диагностики и лечения больных подагрой по Ибн Сине. Учение Ибн Сины в развитии науки. 7- Международные Ибн Синские чтения. Бухара, 2013, С. 83.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Hui M., Carr A., Cameron S. et al. The British Society for Rheumatology Guideline for the Management of Gout. Rheumatology (Oxford). 2017; 56(7): e1-20. doi: 10.1093/rheumatology/kex156.</mixed-citation><mixed-citation xml:lang="en">Hui M., Carr A., Cameron S. et al. The British Society for Rheumatology Guideline for the Management of Gout. Rheumatology (Oxford). 2017; 56(7): e1-20. doi: 10.1093/rheumatology/kex156.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Eliseev M. S. Gout treatment: problems, paradoxes, prospects. Meditsinskiy sovet = Medical Council. 2020;(2):104-108. (In Russ.) doi: 10.21518/2079-701X-2020-2-104-108.@@ Елисеев М. С. Подагра: проблемы, парадоксы, перспективы. Медицинский совет. 2020, № 2. С. 104-108. doi: 10.21518/2079-701X-2020-2-104-108.</mixed-citation><mixed-citation xml:lang="en">Eliseev M. S. Gout treatment: problems, paradoxes, prospects. Meditsinskiy sovet = Medical Council. 2020;(2):104-108. (In Russ.) doi: 10.21518/2079-701X-2020-2-104-108.@@ Елисеев М. С. Подагра: проблемы, парадоксы, перспективы. Медицинский совет. 2020, № 2. С. 104-108. doi: 10.21518/2079-701X-2020-2-104-108.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Nielsena S.M., Zobbea K., Kristensena L. E., Christensen R. Nutritional recommendations for gout: An update from clinical epidemiology. Autoimmun Rev. 2018; 17(11):1090-1096. doi: 10.1016/j.autrev.2018.05.008.</mixed-citation><mixed-citation xml:lang="en">Nielsena S.M., Zobbea K., Kristensena L. E., Christensen R. Nutritional recommendations for gout: An update from clinical epidemiology. Autoimmun Rev. 2018; 17(11):1090-1096. doi: 10.1016/j.autrev.2018.05.008.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Choi H.K. A prescription for lifestyle change in patients with hyperuricemia and gout. Curr Opin Rheumatol. 2010; 22:165-172. doi: 10.1097/ bor.0b013e328335ef38.</mixed-citation><mixed-citation xml:lang="en">Choi H.K. A prescription for lifestyle change in patients with hyperuricemia and gout. Curr Opin Rheumatol. 2010; 22:165-172. doi: 10.1097/ bor.0b013e328335ef38.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Choi H.K., Liu S., Curhan G.Intake of purine-rich foods, protein, and dairy products and relationship to serum levels of uric acid: the Third National Health and Nutrition Examination Survey. Arthritis &amp; Rheumatology. 2005; 52:283-289. doi: 10.1002/art.20761.</mixed-citation><mixed-citation xml:lang="en">Choi H.K., Liu S., Curhan G.Intake of purine-rich foods, protein, and dairy products and relationship to serum levels of uric acid: the Third National Health and Nutrition Examination Survey. Arthritis &amp; Rheumatology. 2005; 52:283-289. doi: 10.1002/art.20761.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang Y., Neogi T., Chen C. et al. Cherry consumption and the risk of recur-rent gout attacks. Arthritis Rheum. 2012; 64(12):4004-4011. doi: 10.1002/ art. 34677.</mixed-citation><mixed-citation xml:lang="en">Zhang Y., Neogi T., Chen C. et al. Cherry consumption and the risk of recur-rent gout attacks. Arthritis Rheum. 2012; 64(12):4004-4011. doi: 10.1002/ art. 34677.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Miao Z., Li C., Chen Y., et al. Dietary and lifestyle changes associated with high prevalence of hyperuricemia and gout in the Shandong coastal cities of Eastern China. J Rheumatol. 2008 Sep;35(9):1859-64. Epub 2008 Jul 15. PMID: 18634142.</mixed-citation><mixed-citation xml:lang="en">Miao Z., Li C., Chen Y., et al. Dietary and lifestyle changes associated with high prevalence of hyperuricemia and gout in the Shandong coastal cities of Eastern China. J Rheumatol. 2008 Sep;35(9):1859-64. Epub 2008 Jul 15. PMID: 18634142.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Craig W.J., Mangels A. R.; American Dietetic Association. Position of the American Dietetic Association: vegetarian diets. J Am Diet Assoc. 2009 Jul;109(7):1266-82. doi: 10.1016/j.jada.2009.05.027.</mixed-citation><mixed-citation xml:lang="en">Craig W.J., Mangels A. R.; American Dietetic Association. Position of the American Dietetic Association: vegetarian diets. J Am Diet Assoc. 2009 Jul;109(7):1266-82. doi: 10.1016/j.jada.2009.05.027.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Choi H.K., Atkinson K., Karlson E. W., Willett W., Curhan G. Purine-rich foods, dairy and protein intake, and the risk of gout in men. N. Engl. J. Med. 2004;350(11):1093-1103. doi: 10.1056/nejmoa035700.</mixed-citation><mixed-citation xml:lang="en">Choi H.K., Atkinson K., Karlson E. W., Willett W., Curhan G. Purine-rich foods, dairy and protein intake, and the risk of gout in men. N. Engl. J. Med. 2004;350(11):1093-1103. doi: 10.1056/nejmoa035700.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Choi H.K., Curhan G. Beer, liquor, and wine consumption and serum uric acid level: the Third National Health and Nutrition Examination Survey. Arthritis Rheum. 2004 Dec 15;51(6):1023-9. doi: 10.1002/art.20821.</mixed-citation><mixed-citation xml:lang="en">Choi H.K., Curhan G. Beer, liquor, and wine consumption and serum uric acid level: the Third National Health and Nutrition Examination Survey. Arthritis Rheum. 2004 Dec 15;51(6):1023-9. doi: 10.1002/art.20821.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Singh J.A., Bharat A., Edwards N. L. An internet survey of common treatments used by patients with gout including cherry extract and juice and other dietary supplements. J Clin Rheumatol. 2015; 21(4):225-226. doi: 10.1097/RHU.0000000000000246.</mixed-citation><mixed-citation xml:lang="en">Singh J.A., Bharat A., Edwards N. L. An internet survey of common treatments used by patients with gout including cherry extract and juice and other dietary supplements. J Clin Rheumatol. 2015; 21(4):225-226. doi: 10.1097/RHU.0000000000000246.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
