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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-214-6-100-104</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-2313</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Гастроинтестинальные нарушения при болезни Паркинсона</article-title><trans-title-group xml:lang="en"><trans-title>Gastrointestinal disorders in Parkinson’s disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7536-2060</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каракулова</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Karakulova</surname><given-names>Yu. V.</given-names></name></name-alternatives><email xlink:type="simple">julia.karakulova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3954-1405</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гольченко</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gol’Chenko</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Пермский государственный медицинский университет имени академика Е. А. Вагнера» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Perm State Medical University n. a. E. A. Wagner of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ «Оренбургский областной клинический психоневрологический госпиталь ветеранов войн»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Orenburg hospital of veterans all wars</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>25</day><month>07</month><year>2023</year></pub-date><volume>0</volume><issue>6</issue><fpage>100</fpage><lpage>104</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Каракулова Ю.В., Гольченко Е.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Каракулова Ю.В., Гольченко Е.А.</copyright-holder><copyright-holder xml:lang="en">Karakulova Y.V., Gol’Chenko E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/2313">https://www.nogr.org/jour/article/view/2313</self-uri><abstract><p>Болезнь Паркинсона (БП) - это неуклонно прогрессирующее нейродегенеративное заболевание нервной системы, которое сочетает в клинической картине «моторные» (двигательные) и «немоторные» проявления. В последние годы много внимания уделяется «немоторным» симптомам БП, важное место среди которых занимают вегетативные. Особое внимание в обзоре уделяется гастроинтестинальным нарушениям, таким как запор, синдром раздраженного кишечника, а также роли микробиоты кишечника в развитии болезни Паркинсона.</p></abstract><trans-abstract xml:lang="en"><p>Parkinson’s disease (PD) is a steadily progressive neurodegenerative disease of the nervous system, which combines “motor” (motor) and “non-motor” manifestations in the clinical picture. In recent years, much attention has been paid to the “non-motor” symptoms of PD, an important place among which is occupied by vegetative ones. The review pays special attention to gastrointestinal disorders, such as constipation, irritable bowel syndrome, as well as the role of the intestinal microbiota in the development of Parkinson’s disease.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>болезнь Паркинсона</kwd><kwd>немоторные симптомы</kwd><kwd>запоры</kwd><kwd>микробиота кишечника</kwd><kwd>вегетативные нарушения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Parkinson’s disease</kwd><kwd>non-motor symptoms</kwd><kwd>constipation</kwd><kwd>intestinal microbiota</kwd><kwd>autonomic disorders</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">de Lau L. M., Breteler M. M. Epidemiology of Parkinson’s disease. Lancet Neurol. 2006 Jun;5(6):525-35. doi: 10.1016/S1474-4422(06)70471-9.</mixed-citation><mixed-citation xml:lang="en">de Lau L. M., Breteler M. M. Epidemiology of Parkinson’s disease. 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