<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-206-10-152-156</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-2171</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>COVID-19</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>COVID-19</subject></subj-group></article-categories><title-group><article-title>Желудочно-кишечный тракт - входные ворота для COVID-19</article-title><trans-title-group xml:lang="en"><trans-title>The gastrointestinal tract is the gate of entrance for COVID-19</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хомерики</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Khomeriki</surname><given-names>N. M.</given-names></name></name-alternatives><email xlink:type="simple">nataliakhomeriki@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Государственное бюджетное учреждение здравоохранения Московской области «Московский областной научно-исследовательский клинический институт им. М. Ф. Владимирского»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Regional Research Clinical Institute of M. Vladimirsky</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>18</day><month>01</month><year>2023</year></pub-date><volume>0</volume><issue>10</issue><fpage>152</fpage><lpage>156</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Хомерики Н.М., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Хомерики Н.М.</copyright-holder><copyright-holder xml:lang="en">Khomeriki N.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/2171">https://www.nogr.org/jour/article/view/2171</self-uri><abstract><p>Доказано, что вирус новой коронавирусной инфекции SARS-CoV-2 проникает в организм не только через дыхательные пути, но и через клетки желудочно-кишечного тракта, на поверхности которых также обнаружены рецепторы (или входные ворота) для вируса, что приводит к повреждения слизистой оболочки желудочно-кишечного тракта. Для лечения новой коронавирусной инфекции для защиты слизистой оболочки используются схемы, включающие в себя гастропротекторные препараты.</p></abstract><trans-abstract xml:lang="en"><p>It has been proven that the virus of the new coronavirus infection SARS-CoV-2 enters the body not only through the respiratory tract, but also through the cells of the gastrointestinal tract, on the surface of which receptors (or entry gates) for the virus are also found, which leads to damage to the mucous membrane gastrointestinal tract. For the treatment of a new coronavirus infection, schemes are used to protect the mucous membrane, including gastroprotective drugs.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>слизистая оболочка желудочно-кишечного тракта</kwd><kwd>гастропротекция</kwd><kwd>Гастрарекс</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>mucous membrane of the gastrointestinal tract</kwd><kwd>gastroprotection</kwd><kwd>Gastrarex</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Grinevich V. B., Kravchuk Yu. A., et al. Management of patients with digestive diseases during the COVID-19 pandemic: Clinical Practice Guidelines by the Gastroenterological Scientifi c Society of Russia. Experimental and Clinical Gastroenterology. 2020;179(7): 4-51. (In Russ.) doi: 10.31146/1682-8658-ecg-179-7-4-51@@ Гриневич В. Б., Кравчук Ю. А., Педь В. И., Сас Е. И., Саликова С. П., Губонина И. В., Ткаченко Е. И., Ситкин С. И., Лазебник Л. Б., Голованова Е. В. Ведение пациентов с заболеваниями органов пищеварения в период пандемии COVID-19. Клинические рекомендации Научного общества гастроэнтерологов России. Экспериментальная и клиническая гастроэнтерология. 2020;179(7): 4-51. DOI: 10.31146/1682-8658-ecg-179-7-4-5.</mixed-citation><mixed-citation xml:lang="en">Grinevich V. B., Kravchuk Yu. A., et al. Management of patients with digestive diseases during the COVID-19 pandemic: Clinical Practice Guidelines by the Gastroenterological Scientifi c Society of Russia. Experimental and Clinical Gastroenterology. 2020;179(7): 4-51. (In Russ.) doi: 10.31146/1682-8658-ecg-179-7-4-51@@ Гриневич В. Б., Кравчук Ю. А., Педь В. И., Сас Е. И., Саликова С. П., Губонина И. В., Ткаченко Е. И., Ситкин С. И., Лазебник Л. Б., Голованова Е. В. Ведение пациентов с заболеваниями органов пищеварения в период пандемии COVID-19. Клинические рекомендации Научного общества гастроэнтерологов России. Экспериментальная и клиническая гастроэнтерология. 2020;179(7): 4-51. DOI: 10.31146/1682-8658-ecg-179-7-4-5.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Mao R., Qiu Y., He J. S., et al. Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis [published correction appears in Lancet Gastroenterol Hepatol. 2020 Jul;5(7): e6]. Lancet Gastroenterol Hepatol. 2020;5(7):667-678. doi: 10.1016/S2468-1253(20)30126-6.</mixed-citation><mixed-citation xml:lang="en">Mao R., Qiu Y., He J. S., et al. Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis [published correction appears in Lancet Gastroenterol Hepatol. 2020 Jul;5(7): e6]. Lancet Gastroenterol Hepatol. 2020;5(7):667-678. doi: 10.1016/S2468-1253(20)30126-6.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Suresh Kumar V. C., Mukherjee S., Harne P. S., et al. Novelty in the gut: a systematic review and meta-analysis of the gastrointestinal manifestations of COVID-19. BMJ Open Gastroenterol. 2020;7(1): e000417. doi: 10.1136/ bmjgast-2020-000417.</mixed-citation><mixed-citation xml:lang="en">Suresh Kumar V. C., Mukherjee S., Harne P. S., et al. Novelty in the gut: a systematic review and meta-analysis of the gastrointestinal manifestations of COVID-19. BMJ Open Gastroenterol. 2020;7(1): e000417. doi: 10.1136/ bmjgast-2020-000417.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Cheung K.S., Hung I. F., Chan P. P. Gastrointestinal Manifestations of SARS-CoV-2 Infection and Virus Load in Fecal Samples from the Hong Kong Cohort and Systematic Review and Meta-analysis. Gastroenterology. 2020 Apr 3: S0016-5085(20)30448-0. doi: 10.1053/j.gastro.2020.03.065.</mixed-citation><mixed-citation xml:lang="en">Cheung K.S., Hung I. F., Chan P. P. Gastrointestinal Manifestations of SARS-CoV-2 Infection and Virus Load in Fecal Samples from the Hong Kong Cohort and Systematic Review and Meta-analysis. Gastroenterology. 2020 Apr 3: S0016-5085(20)30448-0. doi: 10.1053/j.gastro.2020.03.065.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Sultan S., Altayar O., Siddique S. M. AGA Institute Rapid Review of the Gastrointestinal and Liver Manifestations of COVID-19, Meta-Analysis of International Data, and Recommendations for the Consultative Management of Patients with COVID-19. Gastroenterology. 2020 May 11: S0016-5085(20)30593-X. doi: 10.1053/j.gastro.2020.05.001.</mixed-citation><mixed-citation xml:lang="en">Sultan S., Altayar O., Siddique S. M. AGA Institute Rapid Review of the Gastrointestinal and Liver Manifestations of COVID-19, Meta-Analysis of International Data, and Recommendations for the Consultative Management of Patients with COVID-19. Gastroenterology. 2020 May 11: S0016-5085(20)30593-X. doi: 10.1053/j.gastro.2020.05.001.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Parasa S., Desai M., Th oguluva Chandrasekar V., et al. Prevalence of Gastrointestinal Symptoms and Fecal Viral Shedding in Patients With Coronavirus Disease 2019: A Systematic Review and Meta-analysis. JAMA Netw Open. 2020;3(6): e2011335. Published 2020 Jun 1. doi: 10.1001/jamanetworkopen.2020.11335.</mixed-citation><mixed-citation xml:lang="en">Parasa S., Desai M., Th oguluva Chandrasekar V., et al. Prevalence of Gastrointestinal Symptoms and Fecal Viral Shedding in Patients With Coronavirus Disease 2019: A Systematic Review and Meta-analysis. JAMA Netw Open. 2020;3(6): e2011335. Published 2020 Jun 1. doi: 10.1001/jamanetworkopen.2020.11335.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Hoffmann M., Kleine-Weber H., Schroeder S. SARS-CoV- 2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell. 2020 Apr 16;181(2):271-280.e8. doi: 10.1016/j.cell.2020.02.052.</mixed-citation><mixed-citation xml:lang="en">Hoffmann M., Kleine-Weber H., Schroeder S. SARS-CoV- 2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell. 2020 Apr 16;181(2):271-280.e8. doi: 10.1016/j.cell.2020.02.052.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Xu Z., Shi L., Wang Y., et al. Pathological findings of COVID-19 associated with acute respiratory distress syndrome [published correction appears in Lancet Respir Med. 2020 Feb 25]. Lancet Respir Med. 2020;8(4):420-422. doi:10.1016/S2213-2600(20)30076-X.</mixed-citation><mixed-citation xml:lang="en">Xu Z., Shi L., Wang Y., et al. Pathological findings of COVID-19 associated with acute respiratory distress syndrome [published correction appears in Lancet Respir Med. 2020 Feb 25]. Lancet Respir Med. 2020;8(4):420-422. doi:10.1016/S2213-2600(20)30076-X.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Xia L., Wu K. Gastroenterology Practice in COVID-19 Epidemic. World Gastroenterology News. May 2020. pp. 7-10.</mixed-citation><mixed-citation xml:lang="en">Xia L., Wu K. Gastroenterology Practice in COVID-19 Epidemic. World Gastroenterology News. May 2020. pp. 7-10.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Consensus of Diagnosis and Treatment of digestive disorders related to COVID-19. Natl Med J Chin. 2020, Vol. 40: E001. Published Online.</mixed-citation><mixed-citation xml:lang="en">Consensus of Diagnosis and Treatment of digestive disorders related to COVID-19. Natl Med J Chin. 2020, Vol. 40: E001. Published Online.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Grinevich V. B., Kravchuk Yu. A., et al. Features of management of patients with gastroenterological pathology in the conditions of the COVID-19 pandemic. Experimental and Clinical Gastroenterology. 2020;176(4): 3-18. (In Russ.) doi: 10.31146/1682-8658-ecg-176-4-3-18.@@ Гриневич В. Б., Кравчук Ю. А., Ткаченко Е. И., Першко А. М., Педь В. И., Сас Е. И., Губонина И. В., Лазебник Л. Б., Стефанюк О. В. Особенности ведения больных с гастроэнтерологической патологией в условиях пандемии COVID-19. Экспериментальная и клиническая гастроэнтерология. 2020;176(4): 3-18. doi: 10.31146/1682-8658-ecg-176-4-3-18.</mixed-citation><mixed-citation xml:lang="en">Grinevich V. B., Kravchuk Yu. A., et al. Features of management of patients with gastroenterological pathology in the conditions of the COVID-19 pandemic. Experimental and Clinical Gastroenterology. 2020;176(4): 3-18. (In Russ.) doi: 10.31146/1682-8658-ecg-176-4-3-18.@@ Гриневич В. Б., Кравчук Ю. А., Ткаченко Е. И., Першко А. М., Педь В. И., Сас Е. И., Губонина И. В., Лазебник Л. Б., Стефанюк О. В. Особенности ведения больных с гастроэнтерологической патологией в условиях пандемии COVID-19. Экспериментальная и клиническая гастроэнтерология. 2020;176(4): 3-18. doi: 10.31146/1682-8658-ecg-176-4-3-18.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Gu J., Han, B., Wang J. COVID-19: gastrointestinal manifestations and potential fecal-oral transmission. Gastroenterology. 2020 Mar 3. pii: S0016-5085(20)30281-X.</mixed-citation><mixed-citation xml:lang="en">Gu J., Han, B., Wang J. COVID-19: gastrointestinal manifestations and potential fecal-oral transmission. Gastroenterology. 2020 Mar 3. pii: S0016-5085(20)30281-X.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Ivashkin V. T., Sheptulin A. A., Zolnikova O. Yu., et al. New Coronavirus Infection (COVID-19) and Digestive System.Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2020;30(2):3-7. (in Russ.) doi: 10.22416/1382-4376-2020-30-3-7.@@ Ивашкин В. Т., Зольникова О. Ю., Охлобыстин А. В., Полуэктова Е. А., Трухманов А. С., Широкова Е. А., Шептулин А. А., Гоник М. И., Трофимовская Н. И. Новая коронавирусная инфекция (COVID-19) и система органов пищеварения. Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2020; 30(2): 3-7. doi: 10.22416/1382-4376-2020-30-3-7.</mixed-citation><mixed-citation xml:lang="en">Ivashkin V. T., Sheptulin A. A., Zolnikova O. Yu., et al. New Coronavirus Infection (COVID-19) and Digestive System.Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2020;30(2):3-7. (in Russ.) doi: 10.22416/1382-4376-2020-30-3-7.@@ Ивашкин В. Т., Зольникова О. Ю., Охлобыстин А. В., Полуэктова Е. А., Трухманов А. С., Широкова Е. А., Шептулин А. А., Гоник М. И., Трофимовская Н. И. Новая коронавирусная инфекция (COVID-19) и система органов пищеварения. Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2020; 30(2): 3-7. doi: 10.22416/1382-4376-2020-30-3-7.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Lazebnik L.B., Tkachenko E. I., Abdulganiyeva D. I., et al. VI National guidelines for the diagnosis and treatment of acid-related and helicobacter pylori-associated diseases (VI Moscow agreement). Experimental and Clinical Gastroenterology. 2017;(2):3-21. (In Russ.)@@ Лазебник Л. Б., Ткаченко Е. И., Абдулганиева Д. И. и др. VI Национальные рекомендации по диагностике и лечению кислотозависимых и ассоциированных с Helicobacter Pylori заболеваний VI Московские соглашения. Экспериментальная и клиническая гастроэнтерология. - 2017. - № 138 (2). - С. 3-21.</mixed-citation><mixed-citation xml:lang="en">Lazebnik L.B., Tkachenko E. I., Abdulganiyeva D. I., et al. VI National guidelines for the diagnosis and treatment of acid-related and helicobacter pylori-associated diseases (VI Moscow agreement). Experimental and Clinical Gastroenterology. 2017;(2):3-21. (In Russ.)@@ Лазебник Л. Б., Ткаченко Е. И., Абдулганиева Д. И. и др. VI Национальные рекомендации по диагностике и лечению кислотозависимых и ассоциированных с Helicobacter Pylori заболеваний VI Московские соглашения. Экспериментальная и клиническая гастроэнтерология. - 2017. - № 138 (2). - С. 3-21.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Martynov A. I., Sheptulin A. A., Mayev I. V., et al. New Prospects of Cytoprotection in the Treatment and Prevention of Gastric and Intestinal Diseases (Resolution of an Expert Council and Literature Review).Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2020;30(2):7-14. (In Russ.) doi: 10.22416/1382-4376-2020-30-2-7-14.@@ Мартынов А. И., Шептулин А. А., Маев И. В. и др. Новые возможности цитопротекции в лечении и профилактике заболеваний желудка и кишечника (резолюция Экспертного совета и обзор литературы). Рос журнал гастро-энтеро - гепато-колопроктол. - 2020. Т. 30, № 2. - С. 7-14. doi: 10.22416/1382-4376-2020-30-2-7-14.</mixed-citation><mixed-citation xml:lang="en">Martynov A. I., Sheptulin A. A., Mayev I. V., et al. New Prospects of Cytoprotection in the Treatment and Prevention of Gastric and Intestinal Diseases (Resolution of an Expert Council and Literature Review).Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2020;30(2):7-14. (In Russ.) doi: 10.22416/1382-4376-2020-30-2-7-14.@@ Мартынов А. И., Шептулин А. А., Маев И. В. и др. Новые возможности цитопротекции в лечении и профилактике заболеваний желудка и кишечника (резолюция Экспертного совета и обзор литературы). Рос журнал гастро-энтеро - гепато-колопроктол. - 2020. Т. 30, № 2. - С. 7-14. doi: 10.22416/1382-4376-2020-30-2-7-14.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Mazza S., Sorce A., Peyvandi F., Vecchi M., Caprioli F. A fatal case of COVID-19 pneumonia occurring in a patient with severe acute ulcerative colitis. Gut. 2020 Jun;69(6):1148-1149. doi: 10.1136/gutjnl-2020-321183.</mixed-citation><mixed-citation xml:lang="en">Mazza S., Sorce A., Peyvandi F., Vecchi M., Caprioli F. A fatal case of COVID-19 pneumonia occurring in a patient with severe acute ulcerative colitis. Gut. 2020 Jun;69(6):1148-1149. doi: 10.1136/gutjnl-2020-321183.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Mirabito Colafella K. M., Bovee D. M., Danser A. H.J. The rennin-angiotensin-aldosterone system and its therapeutic targets. Exp. Eye Res. 2019 Sep;186:107680. doi: 10.1016/j.exer.2019.05.020.</mixed-citation><mixed-citation xml:lang="en">Mirabito Colafella K. M., Bovee D. M., Danser A. H.J. The rennin-angiotensin-aldosterone system and its therapeutic targets. Exp. Eye Res. 2019 Sep;186:107680. doi: 10.1016/j.exer.2019.05.020.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Bordin D.S., Kiryukova M. A., Shengelia M. I., Kolbasnikov S. V. COVID-19 and Gastrointestinal Tract. Effective pharmacotherapy. Gastroenterology. 2020; (2): 12-16. (in Russ.) doi: 10.33978/2307-3586-2020-16-15-12-16.@@ Бордин Д. С., Кирюкова М. А., Шенгелия М. И., Колбасников С. В. Инфекция COVID-19 и органы пищеварения // Эффективная фармакотерапия. 2020. Т. 16. № 15. С. 12-16. doi: 10.33978/2307-3586-2020-16-15-12-16.</mixed-citation><mixed-citation xml:lang="en">Bordin D.S., Kiryukova M. A., Shengelia M. I., Kolbasnikov S. V. COVID-19 and Gastrointestinal Tract. Effective pharmacotherapy. Gastroenterology. 2020; (2): 12-16. (in Russ.) doi: 10.33978/2307-3586-2020-16-15-12-16.@@ Бордин Д. С., Кирюкова М. А., Шенгелия М. И., Колбасников С. В. Инфекция COVID-19 и органы пищеварения // Эффективная фармакотерапия. 2020. Т. 16. № 15. С. 12-16. doi: 10.33978/2307-3586-2020-16-15-12-16.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">I-Cheng Lee, Teh-Ia Huo, Yi-Hsiang Huang. Gastrointestinal and liver manifestations in patients with COVID-19. Journal of the Chinese Medical Association. 2020; 83 (6): 521-523. doi: 10.1097/JCMA.0000000000000319.</mixed-citation><mixed-citation xml:lang="en">I-Cheng Lee, Teh-Ia Huo, Yi-Hsiang Huang. Gastrointestinal and liver manifestations in patients with COVID-19. Journal of the Chinese Medical Association. 2020; 83 (6): 521-523. doi: 10.1097/JCMA.0000000000000319.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Song Y., Liu P., Shi X. L., et al. SARS-CoV-2 induced diarrhoea as onset symptom in patient with COVID-19. Gut. 2020; 69: 1143-1144. doi: 10.1136/gutjnl-2020-320891.</mixed-citation><mixed-citation xml:lang="en">Song Y., Liu P., Shi X. L., et al. SARS-CoV-2 induced diarrhoea as onset symptom in patient with COVID-19. Gut. 2020; 69: 1143-1144. doi: 10.1136/gutjnl-2020-320891.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Pilat T. L, Radysh I. V., Surovtsev V. V., Korosteleva M. M., Khanferyan R. A. Possibilities of specialized dietary correction of gastrointestinal tract disorders in patients with COVID-19 viral infection. Lechaschi Vrach. 2020;(8): 11-15. (in Russ.) doi: 10.26295/OS.2020.90.44.001.@@ Пилат Т. Л, Радыш И. В., Суровцев В. В., Коростелева М. М., Ханферьян Р. А. Возможности специализированной диетической коррекции нарушений желудочно-кишечного тракта у больных с вирусной инфекцией СOVID-19/. Лечащий врач № 8/2020; 11-15. doi: 10.26295/OS.2020.90.44.001.</mixed-citation><mixed-citation xml:lang="en">Pilat T. L, Radysh I. V., Surovtsev V. V., Korosteleva M. M., Khanferyan R. A. Possibilities of specialized dietary correction of gastrointestinal tract disorders in patients with COVID-19 viral infection. Lechaschi Vrach. 2020;(8): 11-15. (in Russ.) doi: 10.26295/OS.2020.90.44.001.@@ Пилат Т. Л, Радыш И. В., Суровцев В. В., Коростелева М. М., Ханферьян Р. А. Возможности специализированной диетической коррекции нарушений желудочно-кишечного тракта у больных с вирусной инфекцией СOVID-19/. Лечащий врач № 8/2020; 11-15. doi: 10.26295/OS.2020.90.44.001.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Lin L., Jiang X., Zhang Z., et al. Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection. Gut. 2020;69 (6): 997-1001. doi: 10.1136/gutjnl-2020-321013. 18.</mixed-citation><mixed-citation xml:lang="en">Lin L., Jiang X., Zhang Z., et al. Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection. Gut. 2020;69 (6): 997-1001. doi: 10.1136/gutjnl-2020-321013. 18.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Turchina M.S., Mishina A. S., Veremeichik A. L., Reznikov R. G. Clinical features of gastrointestinal tract damage in pations with new coronaviral infection COVID-19. Challenges in modern medicine. 2020;44 (1): 5-15 (in Russ.) doi: 10.18413/2687-0940-2021-44-1-5-15.@@ Турчина М. С., Мишина А. С., Веремейчик А. Л., Резников Р. Г. 2020. Клинические особенности поражения желудочно-кишечного тракта у больных с новой коронавирусной инфекцией COVID-19. Актуальные проблемы медицины. 44 (1): 5-15. doi: 10.18413/2687-0940-2021-44-1-5-15.</mixed-citation><mixed-citation xml:lang="en">Turchina M.S., Mishina A. S., Veremeichik A. L., Reznikov R. G. Clinical features of gastrointestinal tract damage in pations with new coronaviral infection COVID-19. Challenges in modern medicine. 2020;44 (1): 5-15 (in Russ.) doi: 10.18413/2687-0940-2021-44-1-5-15.@@ Турчина М. С., Мишина А. С., Веремейчик А. Л., Резников Р. Г. 2020. Клинические особенности поражения желудочно-кишечного тракта у больных с новой коронавирусной инфекцией COVID-19. Актуальные проблемы медицины. 44 (1): 5-15. doi: 10.18413/2687-0940-2021-44-1-5-15.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Sultan S., Altayar O., Siddique S. M., et al. AGA Institute rapid review of the gastrointestinal and liver manifestations of COVID-19, meta-analysis of international data, and recommendations for the consultative management of patients with COVID-19. Gastroenterology. 2020 Jul;159(1):320-334.e27. doi: 10.1053/j.gastro.2020.05.001.</mixed-citation><mixed-citation xml:lang="en">Sultan S., Altayar O., Siddique S. M., et al. AGA Institute rapid review of the gastrointestinal and liver manifestations of COVID-19, meta-analysis of international data, and recommendations for the consultative management of patients with COVID-19. Gastroenterology. 2020 Jul;159(1):320-334.e27. doi: 10.1053/j.gastro.2020.05.001.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Wang D., Hu B., Hu C. et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China JAMA. 2020 Mar 17;323(11):1061-1069. doi: 10.1001/jama.2020.1585.</mixed-citation><mixed-citation xml:lang="en">Wang D., Hu B., Hu C. et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China JAMA. 2020 Mar 17;323(11):1061-1069. doi: 10.1001/jama.2020.1585.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Epidemiology Working Group for NCIP Epidemic Response, Chinese Center for Disease Control and Prevention. [The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China]. Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Feb 10;41(2):145-151. Chinese. doi: 10.3760/cma.j.issn.0254-6450.2020.02.003.</mixed-citation><mixed-citation xml:lang="en">Epidemiology Working Group for NCIP Epidemic Response, Chinese Center for Disease Control and Prevention. [The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China]. Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Feb 10;41(2):145-151. Chinese. doi: 10.3760/cma.j.issn.0254-6450.2020.02.003.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
