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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-205-9-276-283</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-2066</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>COVID-19</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>COVID-19</subject></subj-group></article-categories><title-group><article-title>Клинико- патогенетические особенности диарейного синдрома, ассоциированного с течением COVID-19</article-title><trans-title-group xml:lang="en"><trans-title>Clinical and pathogenic features of COVID-19- associated diarrhea syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7687-8157</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джулай</surname><given-names>Галина Семеновна</given-names></name><name name-style="western" xml:lang="en"><surname>Dzhulay</surname><given-names>G. S.</given-names></name></name-alternatives><email xlink:type="simple">djoulai@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7926-6749</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джулай</surname><given-names>Татьяна Евгеньевна</given-names></name><name name-style="western" xml:lang="en"><surname>Dzhulay</surname><given-names>T. E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Тверской государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tver State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>07</day><month>10</month><year>2022</year></pub-date><volume>0</volume><issue>9</issue><fpage>276</fpage><lpage>283</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Джулай Г.С., Джулай Т.Е., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Джулай Г.С., Джулай Т.Е.</copyright-holder><copyright-holder xml:lang="en">Dzhulay G.S., Dzhulay T.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/2066">https://www.nogr.org/jour/article/view/2066</self-uri><abstract><p>В статье систематизированы результаты исследований по ключевым направлениям проблемы диареи, ассоциированной с COVID-19, проанализированы сложившиеся представления о клинических характеристиках, патогенетических механизмах и связах с развитием дисбиотических изменений и воспалительных заболеваний кишечника, используемых в практике и перспективных лечебных стратегиях.</p></abstract><trans-abstract xml:lang="en"><p>The article systematizes the results of research in key areas of the problem of diarrhea, associated with COVID-19, analyzes the current ideas about the clinical characteristics, pathogenic mechanisms and relationships with the development of dysbiotic changes and inflammatory bowel diseases, accepted in practice and promising treatment strategies.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>диарейный синдром</kwd><kwd>COVID-19</kwd><kwd>клинические характеристики</kwd><kwd>патогенетические механизмы</kwd><kwd>осложнения</kwd><kwd>лечебные стратегии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diarrhea syndrome</kwd><kwd>COVID-19</kwd><kwd>clinical characteristics</kwd><kwd>pathogenic mechanisms</kwd><kwd>complications</kwd><kwd>treatment strategies</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ivashkin V.T., Sheptulin A. 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