nogrЭкспериментальная и клиническая гастроэнтерологияExperimental and Clinical Gastroenterology1682-8658«Global Media Technologies»10.31146/1682-8658-ecg-205-9-153-160nogr-2052Research ArticleОБЗОРREVIEWРак желчного пузыря: эпидемиология, факторы рискаGallbladder cancer: epidemiology, risk factorshttps://orcid.org/0000-0001-8317-7765ДрукИнна ВикторовнаDrukI. V.noemail@neicon.ruНечаеваГалина ИвановнаNechaevaG. I.noemail@neicon.ruЛялюковаЕлена АлександровнаLyalyukovaE. A.lyalykova@rambler.ruСеменоваЕлена ВладимировнаSemenovaE. V.noemail@neicon.ruФГБОУ ВО «Омский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияOmsk State Medical UniversityRussian Federation20220710202209153160Copyright © Друк И.В., Нечаева Г.И., Лялюкова Е.А., Семенова Е.В., 20222022Друк И.В., Нечаева Г.И., Лялюкова Е.А., Семенова Е.В.Druk I.V., Nechaeva G.I., Lyalyukova E.A., Semenova E.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.nogr.org/jour/article/view/2052

Рак желчного пузыря (РЖП) - редкое, но высоко злокачественное новообразование. Большинство случаев выявляется случайно у пациентов, проходящих обследование по поводу желчнокаменной болезни. Считается, что неблагоприятный прогноз, связанный с РЖП, связан с поздней стадией при постановке диагноза, что обусловлено как анатомическим положением желчного пузыря, так и нечеткостью и неспецифичностью симптомов, что повышает актуальность изучения и освещения данной тематики. Хотя имеющиеся данные подтверждают снижение общей заболеваемости РЖП за последние 30 лет, заболеваемость может увеличиваться у молодых людей. В глобальном масштабе бремя рака желчного пузыря и других видов рака желчевыводящих путей возросло за последние 30 лет. Для РЖП было выявлено несколько факторов риска, многие из которых имеют общие характеристики хронического воспаления желчного пузыря. В статье рассматриваются основные факторы риска и заболевания, предшествующие развитию рака. Цель обзора - представить анализ современных литературных данных об эпидемиологии настоящего заболевания и факторах риска.

Gallbladder cancer (GBC) is a rare but highly malignant neoplasm. Most cases are discovered incidentally in patients undergoing evaluation for gallstone disease. It is believed that an unfavorable prognosis associated with RZD is associated with a late stage at diagnosis, which is due to both the anatomical position of the gallbladder and the vagueness and non-specificity of symptoms, which increases the relevance of studying and highlighting this topic. Although the available evidence supports a decline in the overall incidence of RZD over the past 30 years, the incidence may be increasing in younger people. Globally, the burden of gallbladder and other biliary tract cancers has increased over the past 30 years. Several risk factors have been identified for RGB, many of which share the characteristics of chronic gallbladder inflammation. The article discusses the main risk factors and diseases that precede the development of cancer. The purpose of the review is to present an analysis of current literature data on the epidemiology of this disease and risk factors.

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The authors declare that there are no conflicts of interest present.