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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-205-9-22-28</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-2035</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ ГАСТРОЭНТЕРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL GASTROENTEROLOGY</subject></subj-group></article-categories><title-group><article-title>Рак желудка у больного хроническим гастритом после эрадикации H. pylori: оцениваем риски</article-title><trans-title-group xml:lang="en"><trans-title>Gastric cancer in a patient with chronic gastritis after H. pylori eradication: assessing the risks</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6581-7017</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ливзан</surname><given-names>Мария Анатольевна</given-names></name><name name-style="western" xml:lang="en"><surname>Livzan</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9370-4768</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаус</surname><given-names>Ольга Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Gaus</surname><given-names>O. V.</given-names></name></name-alternatives><email xlink:type="simple">gaus_olga@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7200-7082</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мозговой</surname><given-names>Сергей Игоревич</given-names></name><name name-style="western" xml:lang="en"><surname>Mozgovoi</surname><given-names>S. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Омский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>07</day><month>10</month><year>2022</year></pub-date><volume>0</volume><issue>9</issue><fpage>22</fpage><lpage>28</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ливзан М.А., Гаус О.В., Мозговой С.И., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Ливзан М.А., Гаус О.В., Мозговой С.И.</copyright-holder><copyright-holder xml:lang="en">Livzan M.A., Gaus O.V., Mozgovoi S.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/2035">https://www.nogr.org/jour/article/view/2035</self-uri><abstract><p>Рак желудка занимает лидирующие позиции в структуре онкологической заболеваемости и смертности во всем мире. Ежегодно от рака желудка умирает около 800 тысяч человек. Примерно у двух третей пациентов заболевание диагностируется на поздней стадии, когда проведение радикальных методов лечения становится невозможным. Инфекция Helicobacter pylori (H. pylori) рассматривается в качестве основного этиологического фактора для рака желудка. Для стратификации риска развития рака желудка используется оценка морфологических изменений слизистой оболочки желудка по системе Operative Link for Gastritis Assessment of Atrophic Gastritis (OLGA). В отношении индивидуального риска развития рака желудка ключевую роль играет определение стадии гастрита. Высокую доказательную базу как эффективного метода канцеропревенции имеет эрадикационная терапия H. pylori. Вместе с тем, не у всех пациентов элиминация инфекта может предотвратить развитие рака желудка в будущем. Следовательно, крайне важным является выявление группы лиц с экс-геликобактерным гастритом, имеющих высокий риск развития рака желудка, и проведение у них своевременных мер профилактики. Цель данной публикации обобщить и систематизировать имеющиеся в настоящее время данные о риске развития рака желудка у пациентов с Н. pylori-ассоциированным гастритом, в том числе после успешной эрадикации.</p></abstract><trans-abstract xml:lang="en"><p>Stomach cancer occupies a leading position in oncological morbidity and mortality worldwide. Approximately 800,000 people die from stomach cancer every year. In two-thirds of patients gastric cancer is diagnosed at a late stage, when radical treatment becomes impossible. Helicobacter pylori (H. pylori) infection is considered as the main etiological factor for gastric cancer. To stratify the risk of developing gastric cancer an assessment of morphological changes in the gastric mucosa using the Operative Link for Gastritis Assessment of Atrophic Gastritis (OLGA) system is used. The stage of gastritis plays a key role in determining an individual’s risk of developing stomach cancer. H. pylori eradication therapy is an effective method for preventing gastric cancer. However not in all patients the elimination of the infection can prevent the development of gastric cancer in the future. It is extremely important to identify a group of people with ex-helicobacter gastritis, who have a high risk of developing stomach cancer, and to take timely preventive measures in them. The purpose of this publication is to summarize and systematize the currently available data on the risk of developing gastric cancer in patients with H. pylori-associated gastritis, including those after successful eradication.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак желудка</kwd><kwd>хронический гастрит</kwd><kwd>H. pylori</kwd><kwd>эрадикационная терапия</kwd><kwd>атрофия слизистой оболочки желудка</kwd><kwd>кишечная метаплазия</kwd><kwd>канцеропревенция</kwd><kwd>цитопротекторы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gastric cancer</kwd><kwd>chronic gastritis</kwd><kwd>H. pylori</kwd><kwd>eradication therapy</kwd><kwd>atrophy of the gastric mucosa</kwd><kwd>intestinal metaplasia</kwd><kwd>carcinoprevention</kwd><kwd>cytoprotectors</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">WHO: International Agency for Research on Cancer. Stomach. 2020. 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