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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-198-2-77-85</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-1871</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ ГАСТРОЭНТЕРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL GASTROENTEROLOGY</subject></subj-group></article-categories><title-group><article-title>Пробиотический штамм Bifidobacterium longum BB536 - нутрицевтик широкого профиля</article-title><trans-title-group xml:lang="en"><trans-title>Probiotic strain Bifidobacterium longum BB536 - a nutraceutical of a wide profile</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7663-710X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Громова</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gromova</surname><given-names>O. A.</given-names></name></name-alternatives><email xlink:type="simple">unesco.gromova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2659-7998</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Торшин</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Torshin</surname><given-names>I. Yu.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральный исследовательский центр «Информатика и управление» РАН (ФИЦ ИУ РАН)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Research Center “Informatics and Control” RAS (FRC IU RAS)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>05</day><month>04</month><year>2022</year></pub-date><volume>0</volume><issue>2</issue><fpage>77</fpage><lpage>85</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Громова О.А., Торшин И.Ю., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Громова О.А., Торшин И.Ю.</copyright-holder><copyright-holder xml:lang="en">Gromova O.A., Torshin I.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/1871">https://www.nogr.org/jour/article/view/1871</self-uri><abstract><p>Бифидобактерия B. longum BB536 - безопасный многофункциональный пробиотик с доказанной клинической эффективностью. Модулируя состав микробиома кишечника, штамм ВВ536 проявляет противовоспалительные, антиаллергические, противовирусные, антибактериальные, фунгицидные свойства, показанные в экспериментальных и клинических исследованиях. Показана эффективность применения штамма BB536 в терапии патологии кишечника (для нормализации стула, в терапии язвенного колита, синдрома раздраженного кишечника и др.) а также для нормализации липидного профиля крови и метаболизма жиров.</p></abstract><trans-abstract xml:lang="en"><p>Bifidobacterium B.longum BB536 is a safe multifunctional probiotic with proven clinical efficacy. By modulating the composition of the intestinal microbiome, the BB536 strain exhibits anti-inflammatory, antiallergic, antiviral, antibacterial, fungicidal properties, shown in experimental and clinical studies. The effectiveness of the use of strain BB536 in the treatment of intestinal pathology (for stool normalization, in the treatment of ulcerative colitis, irritable bowel syndrome, etc.), as well as for normalizing the lipid profile of blood and fat metabolism, has been shown.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>пробиотики</kwd><kwd>атеросклероз</kwd><kwd>деконъюгация желчных кислот</kwd><kwd>детоксикация</kwd><kwd>Лактофлорене Холестерол</kwd></kwd-group><kwd-group xml:lang="en"><kwd>probiotics</kwd><kwd>atherosclerosis</kwd><kwd>bile acid deconjugation</kwd><kwd>detoxification</kwd><kwd>Lactoflorene Cholesterol</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">O.A., Torshin I. Yu., Tetruashvili N. K., Serov V. N. 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