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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-195-11-75-78</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-1785</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭКСПЕРИМЕНТАЛЬНАЯ ГАСТРОЭНТЕРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERIMENTAL GASTROENTEROLOGY</subject></subj-group></article-categories><title-group><article-title>Влияние пентагастрина и гастрина-17 на секреторную функцию желудочных желез</article-title><trans-title-group xml:lang="en"><trans-title>Effect of pentagastrin and gastrin-17 on the secretory function of the gastric glands</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8338-1122</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жураева</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhuraeva</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жураева Мохигуль Азимжановна, д. м. н., профессор РАЕ, доцент кафедры ВОП-1 лечебный факультет</p><p>г. Андижан, 170127, ул, Атабекова, 1</p></bio><bio xml:lang="en"><p>Mohigul A. Zhuraeva, MD, Professor of RAE, Associate Professor of the Department of GP-1 Medical Faculty</p><p>Andijan, 170127, Atabekov str., 1</p></bio><email xlink:type="simple">mohigul_azimovna@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алейник</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Aleynik</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алейник Владимир Алексеевич, д. м. н., профессор, профессор кафедры нормальной физиологии</p><p>г. Андижан, 170127, ул, Атабекова, 1</p></bio><bio xml:lang="en"><p>Vladimir A. Aleynik, MD, Professor, Professor of the Department of Normal Physiology</p><p>Andijan, 170127, Atabekov str., 1</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ашуралиева</surname><given-names>Н. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Ashuralieva</surname><given-names>N. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ашуралиева Нилюфар Дильшод кизи, ассистент кафедры пропедевтики внутренних болезней лечебный факультет</p><p>г. Андижан, 170127, ул, Атабекова, 1</p></bio><bio xml:lang="en"><p>Nilufar D. kizi. Ashuralieva, Assistant of the Department of Propaedeutics of Internal Diseases, Faculty of medicine</p><p>Andijan, 170127, Atabekov str., 1</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Холикова</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kholikova</surname><given-names>D. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Холикова Дильрабо Собировна, ассистент кафедры пропедевтики внутренних болезней лечебный факультет</p><p>г. Андижан, 170127, ул, Атабекова, 1</p></bio><bio xml:lang="en"><p>Dilrabo S. Kholikova, Assistant of the Department of Propaedeutics of Internal Diseases, Faculty of medicine</p><p>Andijan, 170127, Atabekov str., 1</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Андижанский государственный медицинский институт (АГМИ)</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>Andijan State Medical Institute (ASMI)</institution><country>Uzbekistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>02</day><month>01</month><year>2022</year></pub-date><volume>0</volume><issue>11</issue><fpage>75</fpage><lpage>78</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Жураева М.А., Алейник В.А., Ашуралиева Н.Д., Холикова Д.С., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Жураева М.А., Алейник В.А., Ашуралиева Н.Д., Холикова Д.С.</copyright-holder><copyright-holder xml:lang="en">Zhuraeva M.A., Aleynik V.A., Ashuralieva N.D., Kholikova D.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/1785">https://www.nogr.org/jour/article/view/1785</self-uri><abstract><p>Регуляцию пищеварительных желез желудка и поджелудочной железы в организме животных и человека обеспечивают пептиды, большинство из которых пребывают в различных молекулярных формах. Установлено 10 молекулярных форм пептидов гастриновой группы и 5 пептидов холецистокининовой (ХЦК) группы, содержащих в своей структуре от 4 до 56 аминокислот, физиологическая роль которых мало изучена. Доказано, что печень выводит до 85% короткоцепочных пептидов гастриновой (пентагастрин) и холецистокининовой (ХЦК-8) групп.</p></abstract><trans-abstract xml:lang="en"><p>The regulation of the digestive glands of the stomach and pancreas in the body of animals and humans is provided by peptides, most of which are in various molecular forms. 10 molecular forms of peptides of the gastrin group and 5 peptides of the cholecystokinin (CCK) group have been identiﬁed, containing in their structure from 4 to 56 amino acids, the physiological role of which has been little studied. It has been proven that the liver removes up to 85% of short-chain peptides of the gastrin (pentagastrin) and cholecystokinin (CCK-8) groups.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>короткоцепочные пептиды</kwd><kwd>холецистокинин</kwd><kwd>гастрин</kwd><kwd>печень</kwd><kwd>гастрин–17</kwd><kwd>утилизация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>short-chain peptides</kwd><kwd>cholecystokinin</kwd><kwd>gastrin</kwd><kwd>liver</kwd><kwd>gastrin-17</kwd><kwd>utilization</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Aleynik V.A., Babich S. M. [The effect of various doses of trypsin on the change in liver utilization of pentagastrin]. Vestnik TMA – Bulletin of TMA, 2013, no. 1, pp. 13–16. (in Russ.)</mixed-citation><mixed-citation xml:lang="en">Aleynik V.A., Babich S. M. 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