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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-195-11-66-74</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-1784</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Нарушения нутритивного статуса и способы его коррекции у больных распространенным раком поджелудочной железы</article-title><trans-title-group xml:lang="en"><trans-title>Nutritional status disorders and methods of their correction in patients with advanced pancreatic cancer</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6946-3826</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кирюкова</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kiryukova</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кирюкова Мария Анатольевна, м. н. с. отделения патологии поджелудочной железы и желчных путей</p><p>111123, г. Москва, шоссе Энтузиастов, 86с6</p></bio><bio xml:lang="en"><p>Maria A. Kiryukova, MD, Junior Research Fellow, Pancreatic and Biliary Diseases Department</p><p>86 bld. 6 Entuziastov shosse, Moscow, 111123</p></bio><email xlink:type="simple">m.kirukova@mknc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6556-7505</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дубцова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dubtsova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дубцова Елена Анатольевна, д. м. н., заведующая отделением патологии поджелудочной железы и желчных путей</p><p>111123, г. Москва, шоссе Энтузиастов, 86с6</p></bio><bio xml:lang="en"><p>Elena A. Dubtsova, MD, PhD, Chair of Pancreatic and Biliary Diseases Department</p><p>86 bld. 6 Entuziastov shosse, Moscow, 111123</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4556-4681</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Винокурова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vinokurova</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Винокурова Людмила Васильевна, д. м. н., вед. науч. сотр. отделения патологии поджелудочной железы и желчных путей</p><p>111123, г. Москва, шоссе Энтузиастов, 86с6</p></bio><bio xml:lang="en"><p>Lyudmila V. Vinokurova, MD, PhD, Leading researcher, Pancreatic and Biliary Diseases Department</p><p>86 bld. 6 Entuziastov shosse, Moscow, 111123</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2480-5191</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малых</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Malykh</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Малых Марина Васильевна, м. н. с. отделения патологии поджелудочной железы и желчных путей</p><p>111123, г. Москва, шоссе Энтузиастов, 86с6</p></bio><bio xml:lang="en"><p>Marina V. Malykh, MD, Junior Research Fellow, Pancreatic and Biliary Diseases Department</p><p>86 bld. 6 Entuziastov shosse, Moscow, 111123</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2815-3992</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бордин</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Bordin</surname><given-names>D. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бордин Дмитрий Станиславович, д. м. н., заведующий отделом патологии поджелудочной железы, желчных путей и верхних отделов пищеварительного тракта; профессор кафедры пропедевтики внутренних болезней и гастроэнтерологии; профессор кафедры поликлинической терапии и семейной медицины факультета последипломного образования</p><p>111123, г. Москва, шоссе Энтузиастов, 86с6</p></bio><bio xml:lang="en"><p>Dmitry S. Bordin, MD, PhD, Head of Department of Pancreatic, Biliary, and Upper Digestive tract disorders; Professor, Chair of Propaedeutics of Internal Diseases and Gastroenterology; Professor, Chair of Outpatient Therapy and Family Medicine, Faculty of Postgraduate Education</p><p>86 bld. 6 Entuziastov shosse, Moscow, 11112320–1 Delegatskaya st., Moscow, 1274734 Sovetskaya st., Tver, 170100</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский клинический научно-практический центр им. А. С. Логинова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Clinical Research Center named after A. S. Loginov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Московский клинический научно-практический центр им. А. С. Логинова; Московский государственный медико-стоматологический университет им. А. И. Евдокимова; Тверской государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Clinical Research Center named after A. S. Loginov; Moscow State University of Medicine and Dentistry named after A. I. Yevdokimov; Tver State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>02</day><month>01</month><year>2022</year></pub-date><volume>0</volume><issue>11</issue><fpage>66</fpage><lpage>74</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кирюкова М.А., Дубцова Е.А., Винокурова Л.В., Малых М.В., Бордин Д.С., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Кирюкова М.А., Дубцова Е.А., Винокурова Л.В., Малых М.В., Бордин Д.С.</copyright-holder><copyright-holder xml:lang="en">Kiryukova M.A., Dubtsova E.A., Vinokurova L.V., Malykh M.V., Bordin D.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/1784">https://www.nogr.org/jour/article/view/1784</self-uri><abstract><p>Несмотря на достигнутый прогресс в лекарственном лечении распространенного рака поджелудочной железы, результаты его лечения и исходы заболевания остаются далекими от удовлетворительных. Особенность лечения мальнутриции у таких пациентов представлена сложностью ее генеза и прогрессивно нарастающей степенью ее проявлений. В обзоре представлены механизмы развития нарушения нутритивного статуса и способы их коррекции.</p></abstract><trans-abstract xml:lang="en"><p>Despite of achieved progress in advanced pancreatic cancer treatment, the disease outcomes remain far from satisfying. The peculiarity of malnutrition treatment in these patients is the result of its causes complexity and progressively growing manifestations extent. The review represents mechanisms of malnutrition and approaches to their treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>нутритивный статус</kwd><kwd>мальнутриция</kwd><kwd>рак поджелудочной железы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>nutritional status</kwd><kwd>malnutrition</kwd><kwd>pancreatic cancer</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kamisawa T., Wood L. D., Itoi T., Takaori K. Pancreatic cancer. Lancet. 2016 Jul 2;388(10039):73–85. doi: 10.1016/S0140–6736(16)00141–0.</mixed-citation><mixed-citation xml:lang="en">Kamisawa T., Wood L. D., Itoi T., Takaori K. Pancreatic cancer. Lancet. 2016 Jul 2;388(10039):73–85. doi: 10.1016/S0140–6736(16)00141–0.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Rawla P., Sunkara T., Gaduputi V. 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