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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-192-8-160-166</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-1724</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Язвенная болезнь у женщин</article-title><trans-title-group xml:lang="en"><trans-title>Pulcer disease in women</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2922-7087</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сагадатова</surname><given-names>Ю. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Sagadatova</surname><given-names>Yu. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сагадатова Юлия Риязовна, аспирант кафедры хирургических болезней</p><p>450112, Республика Башкортостан, г. Уфа, улица 40 лет Октября, 1; Республика Башкортостан, Уфа</p></bio><bio xml:lang="en"><p>Yuliya R. Sagadatova, Postgraduate student of the Department of Surgical Diseases</p><p>450112, Republic of Bashkortostan, Ufa, 40 years of October 1; Republic of Bashkortostan, Ufa, Republic of Bashkortostan, Russia</p></bio><email xlink:type="simple">sagadatovay@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5870-8894</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хасанов</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Khasanov</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хасанов Анвар Гиниятович, д. м. н., профессор, заведующий кафедрой хирургических болезней</p><p>450112, Республика Башкортостан, г. Уфа, улица 40 лет Октября, 1; Республика Башкортостан, Уфа</p></bio><bio xml:lang="en"><p>Anvar G. Khasanov, Doctor of Medical Sciences, Professor, Head of the Department of Surgical Diseases</p><p>450112, Republic of Bashkortostan, Ufa, 40 years of October 1; Republic of Bashkortostan, Ufa, Republic of Bashkortostan, Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8688-8458</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суфияров</surname><given-names>И. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Sufiyarov</surname><given-names>I. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Суфияров Ильдар Фанусович, д. м. н., профессор кафедры хирургических болезней, декан педиатрического факультета</p><p>Республика Башкортостан, Уфа</p></bio><bio xml:lang="en"><p>Ildar F. Sufiyarov, Doctor of Medical Sciences, Professor of the Department of Surgical Diseases, Dean of the Faculty of Pediatrics</p><p>Republic of Bashkortostan, Ufa, Republic of Bashkortostan, Russia</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1890-2865</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фаязов</surname><given-names>Р. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Fayazov</surname><given-names>R. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Фаязов Радик Радифович, д. м. н., профессор кафедры хирургических болезней, ответственный по науке на кафедре</p><p>450112, Республика Башкортостан, г. Уфа, улица 40 лет Октября, 1; Республика Башкортостан, Уфа</p></bio><bio xml:lang="en"><p>Radik R. Fayazov, Doctor of Medical Sciences, Professor of the Department of Surgical Diseases, responsible for science at the Department of Surgical Diseases</p><p>450112, Republic of Bashkortostan, Ufa, 40 years of October 1; Republic of Bashkortostan, Ufa, Republic of Bashkortostan, Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2738-393X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бадретдинов</surname><given-names>А. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Badretdinov</surname><given-names>A. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бадретдинов Азамат Фуатович, к. м.н, доцент кафедры хирургических болезней</p><p>450112, Республика Башкортостан, г. Уфа, улица 40 лет Октября, 1; Республика Башкортостан, Уфа</p></bio><bio xml:lang="en"><p>Azamat F. Badretdinov, Candidate of Medical Sciences, Associate Professor of the Department of Surgical Diseases</p><p>450112, Republic of Bashkortostan, Ufa, 40 years of October 1; Republic of Bashkortostan, Ufa, Republic of Bashkortostan, Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Городская клиническая больница № 8; Башкирский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital No. 8; Bashkir State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Башкирский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bashkir State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>19</day><month>11</month><year>2021</year></pub-date><volume>0</volume><issue>8</issue><fpage>160</fpage><lpage>166</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сагадатова Ю.Р., Хасанов А.Г., Суфияров И.Ф., Фаязов Р.Р., Бадретдинов А.Ф., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Сагадатова Ю.Р., Хасанов А.Г., Суфияров И.Ф., Фаязов Р.Р., Бадретдинов А.Ф.</copyright-holder><copyright-holder xml:lang="en">Sagadatova Y.R., Khasanov A.G., Sufiyarov I.F., Fayazov R.R., Badretdinov A.F.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/1724">https://www.nogr.org/jour/article/view/1724</self-uri><abstract><p>В обзоре представлен анализ литературы по этиологии, патогенезу язвенной болезни желудка и двенадцатиперстной кишки у женщин. Приведены данные по распространенности этих заболеваний в мире и в России. Описаны основные моменты в становлении учения о язвенной болезни. А также, в статье подробно рассматривается теория о половой дифференциации—влияние возраста, менструации, беременности, лактации, менопаузы на язвообразование. Раскрыты взгляды на ключевые механизмы воздействия половых гормонов на желудочно- кишечный тракт.</p></abstract><trans-abstract xml:lang="en"><p>The review presents an analysis of the literature on the etiology and pathophysiology of gastric ulcer and duodenal ulcerin women. Data on the prevalence of these diseases in the world and in Russia are presented. The main points in the formationof the doctrine of peptic ulcer disease are described and the article discusses in detail the theory of sexual diff erentiation -the infl uence of age, menstruation, pregnancy, lactation, menopause on ulceration. Views on the key mechanisms of the eff ect of sex hormones on the gastrointestinal tract are revealed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>язвенная болезнь у женщин</kwd><kwd>язвенная болезнь желудка и двенадцатиперстной кишки</kwd><kwd>эстроген</kwd><kwd>тестостерон</kwd><kwd>эстрогеновые рецепторы</kwd><kwd>обзор литературы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Peptic ulcer in women</kwd><kwd>gastric ulcer and duodenal ulcer</kwd><kwd>estrogen</kwd><kwd>testosterone</kwd><kwd>estrogen receptors</kwd><kwd>literature review</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cовалкин В. И., Биквавова В. Р., Смирнова Л. М., Кокухина Н.С Язвенная болезнь желудка и двенадцатиперстной кишки: история взглядов на патогенез и лечение. Омский научный вестник, 2013, Т. 2, c. 54–58.</mixed-citation><mixed-citation xml:lang="en">Sovalkin  V.I., Bikvavova V. 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