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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-190-6-82-87</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-1680</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ХИРУРГИЧЕСКАЯ ГАСТРОЭНТЕРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SURGICAL GASTROENTEROLOGY</subject></subj-group></article-categories><title-group><article-title>Применение модифицированного тонко-толстокишечного анастомоза «конец-в-бок» у больных с острой обструкцией терминального отдела тонкой и правой половины ободочной кишки</article-title><trans-title-group xml:lang="en"><trans-title>The use of a modified “end-to-side” small intestine anastomosis in patients with acute obstruction of the terminal section of the small and right colon</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8742-0424</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вайнер</surname><given-names>Ю. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Vajner</surname><given-names>Yu. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Вайнер Юрий Сергеевич, к. м. н., доцент кафедры факультетской хирургии</p><p>Россия, 630091, Сибирский федеральный округ, Новосибирская обл., г. Новосибирск, Красный проспект, 52</p></bio><bio xml:lang="en"><p>Yuri S. Vajner, candidate of medical Sciences, docent of the Department of faculty surgery</p><p>630091, Russia, Siberian Federal district, Novosibirsk region, Novosibirsk, Krasny prospect, 52</p></bio><email xlink:type="simple">doctorenco@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Атаманов</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Atamanov</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Атаманов Константин Викторович, д. м. н., доцент, заведующий кафедрой факультетской хирургии</p><p>Россия, 630091, Сибирский федеральный округ, Новосибирская обл., г. Новосибирск, Красный проспект, 52</p></bio><bio xml:lang="en"><p>Konstantin V. Atamanov, doctor of medical Sciences, associate Professor, head of the Department of faculty surgery</p><p>630091, Russia, Siberian Federal district, Novosibirsk region, Novosibirsk, Krasny prospect, 52</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Атаманова</surname><given-names>Э. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Atamanova</surname><given-names>E. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Атаманова Эльвира Радиковна, студент 5 курса лечебного факультета</p><p>Россия, 630091, Сибирский федеральный округ, Новосибирская обл., г. Новосибирск, Красный проспект, 52</p></bio><bio xml:lang="en"><p>El’vira R. Atamanova, 5th year student of the medical faculty</p><p>630091, Russia, Siberian Federal district, Novosibirsk region, Novosibirsk, Krasny prospect, 52</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чеканов</surname><given-names>М. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Chekanov</surname><given-names>M. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чеканов Михаил Николаевич, д. м. н., профессор кафедры общей хирургии</p><p>Россия, 630091, Сибирский федеральный округ, Новосибирская обл., г. Новосибирск, Красный проспект, 52</p></bio><bio xml:lang="en"><p>Mikhail N. Chekanov, doctor of medical Sciences, Professor of the Department of General Surgery</p><p>630091, Russia, Siberian Federal district, Novosibirsk region, Novosibirsk, Krasny prospect, 52</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Верещагин</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Vereshchagin</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Верещагин Евгений Иванович, д. м. н., заведующий кафедрой анестезиологии и реаниматологии им. проф. И. П. Верещагина</p><p>Россия, 630091, Сибирский федеральный округ, Новосибирская обл., г. Новосибирск, Красный проспект, 52</p></bio><bio xml:lang="en"><p>Evgeniy I. Vereshchagin, doctor of medical Sciences Head of the Department of Anesthesiology and Reanimatology named after V.I. prof. I. P. Vereshchagin</p><p>630091, Russia, Siberian Federal district, Novosibirsk region, Novosibirsk, Krasny prospect, 52</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пешкова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Peshkova</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пешкова Инесса Викторовна, д. м. н., доцент кафедры анестезиологии и реаниматологии им. проф. И. П. Верещагина</p><p>Россия, 630091, Сибирский федеральный округ, Новосибирская обл., г. Новосибирск, Красный проспект, 52</p></bio><bio xml:lang="en"><p>Inessa V. Peshkova, doctor of medical Sciences, Associate Professor of the Department of Anesthesiology and Intensive Care. prof. I. P. Vereshchagin</p><p>630091, Russia, Siberian Federal district, Novosibirsk region, Novosibirsk, Krasny prospect, 52</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полякевич</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Polyakevich</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Полякевич Алексей Станиславович, д. м. н., доцент кафедры госпитальной и детской хирургии</p><p>Россия, 630091, Сибирский федеральный округ, Новосибирская обл., г. Новосибирск, Красный проспект, 52</p></bio><bio xml:lang="en"><p>Alexey S. Polyakevich, doctor of medical Sciences Associate Professor of the Department of Hospital and Pediatric Surgery</p><p>630091, Russia, Siberian Federal district, Novosibirsk region, Novosibirsk, Krasny prospect, 52</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования Новосибирский государственный медицинский университет Минздрава России (ФГБОУ ВО НГМУ Минздрава России)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal state budgetary educational institution of higher education Novosibirsk state medical University of the Ministry of health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>31</day><month>08</month><year>2021</year></pub-date><volume>1</volume><issue>6</issue><fpage>82</fpage><lpage>87</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Вайнер Ю.С., Атаманов К.В., Атаманова Э.Р., Чеканов М.Н., Верещагин Е.И., Пешкова И.В., Полякевич А.С., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Вайнер Ю.С., Атаманов К.В., Атаманова Э.Р., Чеканов М.Н., Верещагин Е.И., Пешкова И.В., Полякевич А.С.</copyright-holder><copyright-holder xml:lang="en">Vajner Y.S., Atamanov K.V., Atamanova E.R., Chekanov M.N., Vereshchagin E.I., Peshkova I.V., Polyakevich A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/1680">https://www.nogr.org/jour/article/view/1680</self-uri><abstract><sec><title>Введение</title><p>Введение. Распространенность колоректального рака в мире ежегодно увеличивается. У более 40% пациентов заболевание дебютирует клинической картиной острой кишечной непроходимости, при этом в трети случаев опухоль располагается в правых отделах толстой кишки. Это ведет к необходимости выполнения резекционных или внутренних дренирующих вмешательств, основным этапом которых является тонко-толстокишечный анастомоз. Однако, до 15% таких соустий в конечном итоге являются несостоятельными. Имеется необходимость в разработке способов надежного формирования такого анастомоза.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В исследование включено 37 пациентов с острой кишечной непроходимостью, разделенных на 2 группы(17 и 20 человек). Всем им в качестве хирургического этапа лечения выполняли формирование тонко-толстокишечного анастомоза после правосторонней гемиколэктомии, либо в обходном варианте. Применяли в группе сравнения двухрядный анастомоз «бок-в-бок», в основной группе — однорядный «конец-в-бок» (патент № 2709253). Оценивали частоту развития несостоятельности анастомоза и летальность. Сравнение выполняли с помощью точного критерия Фишера.</p></sec><sec><title>Результаты</title><p>Результаты. В основной группе не было случаев несостоятельности анастомоза и летальности. В группе сравнения — 5 несостоятельностей и 1 смертельный исход.</p></sec><sec><title>Обсуждение</title><p>Обсуждение. При формировании модифицированного тонко-толстокишечного анастомоза сохраняется адекватный кровоток в стенках анастомозируемых петель кишечника, что способствует адекватной регенерации.</p></sec><sec><title>Выводы</title><p>Выводы. Первый опыт клинического применения модифицированного тонко-толстокишечного анастомоза «конец- в-бок» является успешным. Планируется дальнейший набор пациентов и изучение особенностей послеоперационного периода.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. The prevalence of colorectal cancer in the world is increasing every year. In more than 40% of patients, the disease debuts with a clinical picture of acute intestinal obstruction, while in one third of cases the tumor is located in the right half of the colon. This leads to the necessity to perform colon resection or bypass surgery, the main stage of which is making entero- colic anastomosis. However, up to 15% of these anastomoses has a leakage. Development of methods of forming a reliable anastomosis is thus critical.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. 37 patients with acute intestinal obstruction, divided into 2 groups (17 and 20 people), are included into the study. All of them, as a surgical stage of treatment, underwent a right hemicolectomy with the formation of an entero- colic anastomosis or a bypass surgery. A double-row side-to-side anastomosis was used in the comparison group, and a single-row “end-to-side” anastomosis in the main group (patent No. 2709253). The incidence of anastomotic leakage and mortality were assessed. Comparison was performed using Fisher’s exact test.</p></sec><sec><title>Results</title><p>Results. There were no cases of anastomotic leakage and mortality in the main group. In the comparison group, there were 5 leakages and 1 death.</p></sec><sec><title>Discussion</title><p>Discussion. When a modified entero-colic anastomosis is formed, adequate blood flow is maintained in the walls of the anastomosed intestinal loops, which contributes to adequate regeneration.</p></sec><sec><title>Conclusion</title><p>Conclusion. The first clinical experience with the modified end-to-side entero- colic anastomosis is successful. It is planned to further recruit patients and study the features of the postoperative period.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>тонко-толстокишечный анастомоз</kwd><kwd>острая кишечная непроходимость</kwd><kwd>несостоятельность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>entero-colic anastomosis</kwd><kwd>acute intestinal obstruction</kwd><kwd>anastomotic leakage</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Состояние онкологической помощи населению России в 2019 году под редакцией А. Д. Каприна, В. В. Старинского, А. О. Шахзадовой. Москва. 2020.</mixed-citation><mixed-citation xml:lang="en">Kaprin A.D., Starinski V. V., Petrova G. V. Sostoyaniye onkologicheskoy pomoshchi naseleniyu Rossii v 2019 godu [A condition of the oncological help to the population of Russia in 2019]. Moscow. 2020. 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