nogrЭкспериментальная и клиническая гастроэнтерологияExperimental and Clinical Gastroenterology1682-8658«Global Media Technologies»10.31146/1682-8658-ecg-189-5-57-69nogr-1659Research ArticleОБЗОРREVIEWНутритивный статус и состав тела детей с муковисцидозомNutritional status and body composition in children with Cystic Fibrosishttps://orcid.org/0000-0001-9430-3448СоколовИ.SokolovI.

Соколов Ина, аспирант отделения пульмонологии

Москва, Россия

Ina Sokolov, postgraduate student of the department of pulmonology

119991 Moscow, Russia

ina.sokolova.1985@mail.ruhttps://orcid.org/0000-0002-2367-9920СимоноваО. И.SimonovaO. I.

Симонова О. И., д. м. н., профессор, заведующая отделением пульмонологии

Москва, Россия

Olga I. Simonova, Doctor of Medical Sciences, Professor, Head of the Department of Pulmonology

119991 Moscow, Russia

Moscow, Russia

https://orcid.org/0000-0002-3993-1246РославцеваЕ. А.RoslavtsevaE. A.

Рославцева Е. А., к. м. н, старший научный сотрудник лаборатории питания здорового и больного ребенка

Москва, Россия

Elena A. Roslavtseva, Ph. D., Senior Researcher, Laboratory of Healthy and Sick Child Nutrition

119991 Moscow, Russia

https://orcid.org/0000-0002-6529-958XЧерневичВ. П.ChernevichV. P.

Черневич В. П., младший научный сотрудник Лаборатории редких и наследственных болезний у детей

Москва, Россия

Vera P. Chernevich, researcher, Laboratory of Rare and Hereditary Diseases in Children

119991 Moscow, Russia

https://orcid.org/0000-0002-3977-0657БушуеваТ. В.VinokurovaA. V.

Бушуева Т. В., д. м. н., ведущий научный сотрудник лаборатории питания здорового и больного ребенка

Москва, Россия

Anya V. Vinokurova, resident

119991 Moscow, Russia

ВинокуроваА. В.BushuevaT. V.

Винокурова А. В., ординатор

Москва, Россия

Tatiana V. Bushueva, Doctor of Medical Sciences, Leading Researcher of the Laboratory of Healthy and Sick Child Nutrition

119991 Moscow, Russia

Moscow, Russia

БоровикТ. Э.BorovikT. E.

Боровик Т. Э., д. м. н., профессор, заведующая лабораторией питания здорового и больного ребенка

Москва, Россия

Tatiana E. Borovik, Doctor of Medical Sciences, Professor, Head of the Laboratory for Healthy and Sick Child Nutrition

119991 Moscow, Russia

Moscow, Russia

https://orcid.org/0000-0002-6182-0788ПоляковС. Д.PolyakovS. D.

Поляков С. Д., д. м. н., профессор

Москва, Россия

Sergey D. Polyakov, Doctor of Medical Sciences, Professor

119991 Moscow, Russia

ФГАУ «Национальный медицинский центр здоровья детей» МЗ РФРоссияNational Medical Research Center for Children’s Health Federal State Autonomous Institution of the Ministry of Health of the Russian FederationRussian FederationФГАУ «Национальный медицинский центр здоровья детей» МЗ РФ; Первый Московский государственный медицинский университет им. И. М. Сеченова МЗ РФ (Сеченовский университет)РоссияNational Medical Research Center for Children’s Health Federal State Autonomous Institution of the Ministry of Health of the Russian Federation; First Moscow State Medical Sechenov UniversityRussian FederationФГАУ «Национальный медицинский центр здоровья детей» МЗ РФ; ФГБУ Медико- генетический научный центр им. акад. Н. П. БочковаРоссияNational Medical Research Center for Children’s Health Federal State Autonomous Institution of the Ministry of Health of the Russian FederationRussian FederationФГАУ «Национальный медицинский центр здоровья детей» МЗ РФРоссияNational Medical Research Center for Children’s Health Federal State Autonomous Institution of the Ministry of Health of the Russian Federation; Medical Genetic Research CenterRussian FederationФГАУ «Национальный медицинский центр здоровья детей» МЗ РФ; Первый Московский государственный медицинский университет им. И. М. Сеченова МЗ РФ (Сеченовский университет)РоссияNational Medical Research Center for Children’s Health Federal State Autonomous Institution of the Ministry of Health of the Russian Federation; Moscow State Medical Sechenov UniversityRussian Federation202119082021155769Copyright © Соколов И., Симонова О.И., Рославцева Е.А., Черневич В.П., Бушуева Т.В., Винокурова А.В., Боровик Т.Э., Поляков С.Д., 20212021Соколов И., Симонова О.И., Рославцева Е.А., Черневич В.П., Бушуева Т.В., Винокурова А.В., Боровик Т.Э., Поляков С.Д.Sokolov I., Simonova O.I., Roslavtseva E.A., Chernevich V.P., Vinokurova A.V., Bushueva T.V., Borovik T.E., Polyakov S.D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.nogr.org/jour/article/view/1659

Сохранная функция лёгких, определяющая прогноз заболевания у больных муковисцидозом (МВ), напрямую зависит от нутритивного статуса пациента. Считается, что нормальный индекс массы тела (ИМТ) для данного возраста/пола пациента свидетельствует о нормальном нутритивном статусе. Однако известно, что у больных МВ только безжировая масса тела (костно-мышечная и висцеральная) напрямую коррелирует с функцией легких. Метод оценки состава тела у детей с муковисцидозом с помощью биоимпедансометрии является современным, информативным и доступным в педиатрической практике. Показатели состава тела можно использовать у этих пациентов не только с диагностической и прогностической целью, но и для мониторинга за течением болезни у конкретного больного, составления программы коррекции питания и двигательной активности.

Биоимпедансный метод оценки состава тела детей с муковицидозом, проведенный в данной работе, показывает, что у детей с нормальным и даже низким ИМТ процент безжировой/тощей массы тела оказывается низким, что требует мер по увеличению мышечной/костной массы, особенно — силе дыхательной мускулатуры, как путем коррекции белкового компонента рациона, так и по увеличению физической/спортивной активности, в дополнение к обязательной кинезитерапии.

The pulmonary function which determines the prognosis of the disease in patients with cystic fibrosis (CF) depends directly on their nutritional status. Normal body mass index (BMI) for a given age/sex of the patient is considered to correspond with normal nutritional status. However, it is known that in CF patients only lean body mass (musculoskeletal and visceral) correlates directly with lung function. Bioimpedansometry, as the he method for assessing body composition in children with cystic fibrosis is actual, informative and available in pediatric practice. Body composition indicators can be used in these patients not only for diagnostic and prognostic purposes, but also for monitoring the course of the disease in a particular patient and correction of nutrition.

The estimation of body composition with bioimpedance method in children with CF, carried out in this study, shows that in children with normal and even low BMI, the percentage of lean body mass is low, which requires measures to increase muscle/bone mass, the strength of the respiratory muscles especially, both by correcting the protein component of the diet, and by increasing physical / sports activity, in addition to compulsory respiratory physiotherapy.

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The authors declare that there are no conflicts of interest present.