<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-188-4-150-154</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-1641</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Целиакия: некариозные поражения зубов</article-title><trans-title-group xml:lang="en"><trans-title>Celiac disease: non-carious lesions of the teeth</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орешко</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Oreshko</surname><given-names>L. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Орешко Людмила Саварбековна, доктор медицинских наук, профессор, врач-терапевт, гастроэнтеролог, аллерголог высшей квалификационной категории</p><p>191015, st. Kirochnaya, 41, St. Petersburg</p></bio><bio xml:lang="en"><p>Lyudmila S. Oreshko, Doct. of Med Sci., professor, therapist, gastroenterologist, allergist of the highest qualification category</p><p>191015, st. Kirochnaya, 41, St. Petersburg</p></bio><email xlink:type="simple">oreshkol@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алиева</surname><given-names>Г. Ч.</given-names></name><name name-style="western" xml:lang="en"><surname>Alieva</surname><given-names>G. Ch.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алиева Гюнель Чингизовна, студентка 4 курса</p><p>191015, st. Kirochnaya, 41, St. Petersburg</p></bio><bio xml:lang="en"><p>Gunel Ch. Alieva, 4th year student</p><p>191015, st. Kirochnaya, 41, St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО СЗГМУ им. И. И. Мечникова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Mechnikov North-West State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>20</day><month>07</month><year>2021</year></pub-date><volume>0</volume><issue>4</issue><fpage>150</fpage><lpage>154</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Орешко Л.С., Алиева Г.Ч., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Орешко Л.С., Алиева Г.Ч.</copyright-holder><copyright-holder xml:lang="en">Oreshko L.S., Alieva G.C.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/1641">https://www.nogr.org/jour/article/view/1641</self-uri><abstract><p>Большая распространенность некариозных проявлений у больных целиакией описана многочисленными авторами, которые рассматриваются как диагностический ключ к атипичным формам целиакии. К проявлениям, тесно связанным с целиакией, относятся: дефекты зубной эмали, патологическая стираемость зубов, как нарушение минерализации зубных коронок, и морфофункциональные дефекты твердых тканей зубов.</p><sec><title>Материалы и методы</title><p>Материалы и методы. Были обсмотрены 45 пациентов в возрасте от 23 до 36 лет с диагнозом целиакии, установленным на основании результатов клинико- анамнестического, генетического, инструментального исследований, морфологического изучения биоптата слизистой оболочки кишки.</p></sec><sec><title>Результат</title><p>Результат. Обследование зубочелюстной системы больных показало, что у 100% обследованных патологическая стираемость зубной эмали. У 32 пациентов выявлена скученность зубов. У 5 пациентов диагностирована частичная симметричная адентия врожденного характера.</p></sec><sec><title>Вывод</title><p>Вывод. Выявленные зубочелюстные аномалии можно отнести к оральным проявлениям целиакии, являющиеся диагностическим критерием при подозрении заболевания.</p></sec></abstract><trans-abstract xml:lang="en"><p>The high prevalence of non-carious manifestations in patients with celiac disease is described by numerous authors, who are considered as a diagnostic key to atypical forms of celiac disease. The manifestations closely associated with celiac disease include: defects in tooth enamel, pathological tooth abrasion, as a violation of the mineralization of dental crowns, and morphofunctional defects in the hard tissues of the teeth.</p><sec><title>Materials and methods</title><p>Materials and methods. We examined 45 patients aged 23 to 36 years with a diagnosis of celiac disease, established on the basis of the results of clinical anamnestic, genetic, instrumental studies, morphological study of a biopsy specimen of the intestinal mucosa.</p></sec><sec><title>Result</title><p>Result. Examination of the dentition of the patients showed that 100% of the examined had pathological abrasion of tooth enamel. Crowded teeth were found in 32 patients. Partial symmetric congenital adentia was diagnosed in 5 patients.</p></sec><sec><title>Conclusion</title><p>Conclusion. The revealed dentoalveolar anomalies can be attributed to oral manifestations of celiac disease, which is a diagnostic criterion for suspected disease.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>целиакия</kwd><kwd>кариес</kwd><kwd>зубная эмаль</kwd><kwd>оральные проявления</kwd></kwd-group><kwd-group xml:lang="en"><kwd>celiac disease</kwd><kwd>caries</kwd><kwd>tooth enamel</kwd><kwd>oral manifestations</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Патологическое стирание зубов / В. А. Алексеев, А. М. Брозголь. – Москва: Медицина, 1970. – 88 с.</mixed-citation><mixed-citation xml:lang="en">Alekseev V. A., Brozgol A. M. Patologicheskoe stiranie zubov [Pathological tooth abrasion]. Moscow, Medicine publ., 1970. 88 p.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Стоматология. Международная классификация болезней. Клиническая характеристика нозологических форм: учеб. пособие / М. Я. Алимова и др. – М.: ГЭОТАР-Медиа, 2016. – 204 с.</mixed-citation><mixed-citation xml:lang="en">Alimova M.Y. et al. Stomatologia. Mezhdunarodnaya klasifi katsia bolezney. Klinicheskaya harakteristika nozologicheskih form. [Dentistry. International classification of diseases. Clinical characteristics of nosological forms]. Moscow, GEOTAR-Media Publ., 2016. 204 p.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Казеко, Л. А. Повышенное стирание зубов: учеб.-метод. пособие / Л. А. Казеко, О. А. Круглик. – Минск: БГМУ, 2009. – 48 с.</mixed-citation><mixed-citation xml:lang="en">Kazeko L.A., Kruglik O. A. Povishenoe stiranie zubov. [Increased abrasion of teeth]. Minsk, BSMU, 2009. 48 p.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Грошиков, М. И. Некариозные поражения тканей зуба / М. И. Грошиков. – М.: Медицина, 1985. – 172 с.</mixed-citation><mixed-citation xml:lang="en">Groshikov M. I. Nekariozniye porazhenia tkaney zuba. [Non-carious lesions of tooth tissues]. Moscow, Medicine Publ., 1985. 172 p.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Мышечно- суставная дисфункция и её взаимосвязь с окклюзионными нарушениями / В. В. Коннов, Е. Н. Пичугина, Е. С. Попко, А. Р. Арушанян, Э. В. Пылаев // Современные проблемы науки и образования. – 2015. – № 6. – С. 199.</mixed-citation><mixed-citation xml:lang="en">Konnov V.V., Pichugina E. N., Popko E. S., Arushanyan A. R., Pilaev E. V. Mishechno- sustavnaya disfunkcia i yeyo vzaimosvaz s okluzionimi narusheniyami. [Musculo- articular dysfunction and its relationship with occlusive disorders]. Sovremeniyi problemi nauki i obrazovania. 2015, no 6, 199 p.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Wierink C.D., van Diermen D. E., Aartman I. H., Heymans H. S. Dental enamel defects in children with coeliac disease. Int. J. Paediatr. Dent. 2007;17(3):163–168. doi: 10.1111/j.1365–263X.2006.00816.x</mixed-citation><mixed-citation xml:lang="en">Wierink C.D., van Diermen D. E., Aartman I. H., Heymans H. S. Dental enamel defects in children with coeliac disease. Int. J. Paediatr. Dent. 2007;17(3):163–168. doi: 10.1111/j.1365–263X.2006.00816.x</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Cheng J., Malahias T., Brar P., Minaya M. T., Green P. H. Th e association between celiac disease, dental enamel defects, and aphthous ulcers in a United States cohort. J. Clin. Gastroenterol. 2010;44(3):191–194. doi: 10.1097/MCG.0b013e3181ac9942</mixed-citation><mixed-citation xml:lang="en">Cheng J., Malahias T., Brar P., Minaya M. T., Green P. H. Th e association between celiac disease, dental enamel defects, and aphthous ulcers in a United States cohort. J. Clin. Gastroenterol. 2010;44(3):191–194. doi: 10.1097/MCG.0b013e3181ac9942</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Procaccini M., Campisi G., Bufo P., Compilato D., Massaccesi C., Catassi C., Lo Muzio L. Lack of association between celiac disease and dental enamel hypoplasia in a case-control study from an Italian central region. Head Face Med. 2007;3:25. doi: 10.1186/1746–160X-3–25</mixed-citation><mixed-citation xml:lang="en">Procaccini M., Campisi G., Bufo P., Compilato D., Massaccesi C., Catassi C., Lo Muzio L. Lack of association between celiac disease and dental enamel hypoplasia in a case-control study from an Italian central region. Head Face Med. 2007;3:25. doi: 10.1186/1746–160X-3–25</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Avşar A., Kalayci A. G. Th e presence and distribution of dental enamel defects and caries in children with celiac disease. Turk. J. Pediatr. 2008;50(1):45–50.</mixed-citation><mixed-citation xml:lang="en">Avşar A., Kalayci A. G. Th e presence and distribution of dental enamel defects and caries in children with celiac disease. Turk. J. Pediatr. 2008;50(1):45–50.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Cantekin K, Arslan D, Delikan E. Presence and distribution of dental enamel defects, recurrent aphthous lesions and dental caries in children with celiac disease. Pak J Med Sci. 2015;31(3):606–9. doi: 10.12669/pjms.313.6960. PMID: 26150853; PMCID: PMC4485280.</mixed-citation><mixed-citation xml:lang="en">Cantekin K, Arslan D, Delikan E. Presence and distribution of dental enamel defects, recurrent aphthous lesions and dental caries in children with celiac disease. Pak J Med Sci. 2015;31(3):606–9. doi: 10.12669/pjms.313.6960. PMID: 26150853; PMCID: PMC4485280.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Bramanti E, Cicciù M, Matacena G, Costa S, Magazzù G. Clinical Evaluation of Specific Oral Manifestations in Pediatric Patients with Ascertained versus Potential Coeliac Disease: A Cross- Sectional Study. Gastroenterol Res Pract. 2014;2014:934159. doi: 10.1155/2014/934159. Epub 2014 Aug 13. PMID: 25197270; PMCID: PMC4147289.</mixed-citation><mixed-citation xml:lang="en">Bramanti E, Cicciù M, Matacena G, Costa S, Magazzù G. Clinical Evaluation of Specific Oral Manifestations in Pediatric Patients with Ascertained versus Potential Coeliac Disease: A Cross- Sectional Study. Gastroenterol Res Pract. 2014;2014:934159. doi: 10.1155/2014/934159. Epub 2014 Aug 13. PMID: 25197270; PMCID: PMC4147289.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Bossù M, Bartoli A, Orsini G, Luppino E, Polimeni A. Enamel hypoplasia in coeliac children: a potential clinical marker of early diagnosis. Eur J Paediatr Dent. 2007 Mar;8(1):31–7. PMID: 17359212.</mixed-citation><mixed-citation xml:lang="en">Bossù M, Bartoli A, Orsini G, Luppino E, Polimeni A. Enamel hypoplasia in coeliac children: a potential clinical marker of early diagnosis. Eur J Paediatr Dent. 2007 Mar;8(1):31–7. PMID: 17359212.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Krzywicka B., Herman K., Kowalczyk- Zając M., Pytrus T. Celiac disease and its impact on the oral health status–review of the literature. Adv. Clin. Exp. Med. 2014; 23(5):675–681. doi: 10.17219/acem/37212</mixed-citation><mixed-citation xml:lang="en">Krzywicka B., Herman K., Kowalczyk- Zając M., Pytrus T. Celiac disease and its impact on the oral health status–review of the literature. Adv. Clin. Exp. Med. 2014; 23(5):675–681. doi: 10.17219/acem/37212</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Carvalho F. K., de Queiroz A. M., Bezerra da Silva R. A., Sawamura R., Bachmann L., Bezerra da Silva L. A., Nelson- Filho P. Oral aspects in celiac disease children: Clinical and dental enamel chemical evaluation. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. 2015;119(6):636–643. doi: 10.1016/j.oooo.2015.02.483</mixed-citation><mixed-citation xml:lang="en">Carvalho F. K., de Queiroz A. M., Bezerra da Silva R. A., Sawamura R., Bachmann L., Bezerra da Silva L. A., Nelson- Filho P. Oral aspects in celiac disease children: Clinical and dental enamel chemical evaluation. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. 2015;119(6):636–643. doi: 10.1016/j.oooo.2015.02.483</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Muñoz F., Del Río N., Sóñora C., Tiscornia I., Marco A., Hernández A. Enamel defects associated with coeliac disease: Putative role of antibodies against gliadin in pathogenesis. Eur. J. Oral Sci. 2012;120(2):104–112. doi: 10.1111/j.1600–0722.2012.00949.x</mixed-citation><mixed-citation xml:lang="en">Muñoz F., Del Río N., Sóñora C., Tiscornia I., Marco A., Hernández A. Enamel defects associated with coeliac disease: Putative role of antibodies against gliadin in pathogenesis. Eur. J. Oral Sci. 2012;120(2):104–112. doi: 10.1111/j.1600–0722.2012.00949.x</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Hill I. D., Dirks M. H., Liptak G. S., Colletti R. B., Fasano A., Guandalini S., Hoffenberg E. J., Horvath K., Murray J. A., Pivor M., Seidman E. G. North American Society for pediatric gastroenterology, hepatology and nutrition. guideline for the diagnosis and treatment of celiac disease in children: Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J. Pediatr. Gastroenterol. Nutr. 2005;40(1):1–19. doi: 10.1097/00005176–200501000–00001</mixed-citation><mixed-citation xml:lang="en">Hill I. D., Dirks M. H., Liptak G. S., Colletti R. B., Fasano A., Guandalini S., Hoffenberg E. J., Horvath K., Murray J. A., Pivor M., Seidman E. G. North American Society for pediatric gastroenterology, hepatology and nutrition. guideline for the diagnosis and treatment of celiac disease in children: Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J. Pediatr. Gastroenterol. Nutr. 2005;40(1):1–19. doi: 10.1097/00005176–200501000–00001</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">El- Hodhod MA, El- Agouza IA, Abdel- Al H, Kabil NS, Bayomi KA. Screening for celiac disease in children with dental enamel defects. ISRN Pediatr. 2012;2012:763783. doi: 10.5402/2012/763783. Epub 2012 Jun 7. PMID: 22720168; PMCID: PMC3376764.</mixed-citation><mixed-citation xml:lang="en">El- Hodhod MA, El- Agouza IA, Abdel- Al H, Kabil NS, Bayomi KA. Screening for celiac disease in children with dental enamel defects. ISRN Pediatr. 2012;2012:763783. doi: 10.5402/2012/763783. Epub 2012 Jun 7. PMID: 22720168; PMCID: PMC3376764.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Некариозные поражения зуба: учеб.-метод. пособие для преподавателей и студентов стом. фак-та / под ред. Н. Н. Гаража. – Ставрополь, 2011. – 33 с.</mixed-citation><mixed-citation xml:lang="en">Garazh N. N. Nekarioznie porazheniya zuba. [Noncarious tooth lesions]. Stavropol, 2011. 33 p.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Сесорова И. С., Шниткова Е. В., Лазоренко Т. В., Здорикова М. А., Подосенкова А. А. Дисплазия соединительной ткани как фактор риска развития зубочелюстных аномалий // Современные проблемы науки и образования. – 2016. – № 6.</mixed-citation><mixed-citation xml:lang="en">Sesorova  I.S., Shnitkova E. V., Lazorenko T. V., Zdorikova M. A., Podosenkova A. A. Connective tissue dysplasia as a risk factor for the development the dentalveolar of anomalies. Sovremeniyi problemi nauki i obrazovania. 2016, no 6.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
