nogrЭкспериментальная и клиническая гастроэнтерологияExperimental and Clinical Gastroenterology1682-8658«Global Media Technologies»10.31146/1682-8658-ecg-188-4-84-95nogr-1633Research ArticleПЕРЕДОВАЯ СТАТЬЯLEADING ARTICLEСовременное представление о целиакии взрослыхModern understanding of adult celiac diseasehttps://orcid.org/0000-0002-2726-9996ОрешкоЛ. С.OreshkoL. S.

Орешко Людмила Саварбековна, доктор медицинских наук, профессор кафедры пропедевтики внутренних болезней, гастроэнтерологии и диетологии им. С. М. Рысса

191015, ул. Кирочная д. 41, Санкт- Петербург

Ludmila S. Оrеshkо, MD, professor of the Department of Internal Medicine Propedeutics, Gastroenterology and Dietetics n. a. S. M. Ryss

191015, Kirochnay street, 41, Saint- Petersburg

Scopus ID: 24081182800

oreshkol@yandex.ruБакулинИ. Г.BakulinI. G.

 

Бакулин Игорь Геннадьевич, доктор медицинских наук, профессор, заведующий кафедрой пропедевтики внутренних болезней, гастроэнтерологии и диетологии им. С. М. Рысса

191015, ул. Кирочная д. 41, Санкт- Петербург

Igor G. Bakulin, doctor of Medical Sciences, Professor, Head of the Department of Internal Medicine Propedeutics, Gastroenterology and Dietetics n. a. S. M. Ryss

191015, Kirochnay street, 41, Saint- Petersburg

https://orcid.org/0000-0001-6011-0998АвалуеваЕ. Б.AvaluevaE. B.

Авалуева Елена Борисовна, доктор медицинских наук, профессор кафедры пропедевтики внутренних болезней, гастроэнтерологии и диетологии им. С. М. Рысса

191015, ул. Кирочная д. 41, Санкт- Петербург

Elena B. Avalueva, doctor of Medical Sciences, Professor of the Department of Internal Medicine Propedeutics, Gastroenterology and Dietetics n. a. S. M. Ryss

191015, Kirochnay street, 41, Saint- Petersburg

https://orcid.org/0000-0001-7606-2556СеменоваЕ. А.SemenovaE. A.

Семенова Елена Анатольевна, кандидат медицинских наук, ассистент кафедры пропедевтики внутренних болезней, гастроэнтерологии и диетологии им. С. М. Рысса

191015, ул. Кирочная д. 41, Санкт- Петербург

Elena A. Semenova, candidate of medical sciences, assistant of the Department of Internal Medicine Propedeutics, Gastroenterology and Dietetics n. a. S. M. Ryss

191015, Kirochnay street, 41, Saint- Petersburg

Scopus ID: 56677811200

https://orcid.org/0000-0003-0331-0963СиткинС. И.SitkinS. I.

Ситкин Станислав Игоревич, кандидат медицинских наук, доцент кафедры пропедевтики внутренних болезней, гастроэнтерологии и диетологии им. С. М. Рысса; заведующий НИГ эпигенетики и метагеномики Института перинатологии и педиатрии

191015, ул. Кирочная д. 41, Санкт- Петербург, 

197341, ул. Аккуратова, 2, Санкт- Петербург

Stanislav I. Sitkin, Doctor of Medicine, Associate Professor of the Department of Internal Medicine Propedeutics, Gastroenterology and Dietetics n. a. S. M. Ryss; Head of the Epigenetics & Metagenomics Research Group of the Institute of Perinatology and Pediatrics

191015, Kirochnay street, 41, Saint- Petersburg, 

Akkuratova St., 2, St. Petersburg 197341

СПб ФГБОУ ВО СЗГМУ им. И. И. МечниковаРоссияNorth- Western State Medical University named after I. I. Mechnikov, Ministry of Health of Russian FederationRussian FederationСПб ФГБОУ ВО СЗГМУ им. И. И. Мечникова; ФГБУ «Национальный медицинский исследовательский центр имени В. А. Алмазова» Министерства здравоохранения Российской ФедерацииРоссияNorth- Western State Medical University named after I. I. Mechnikov, Ministry of Health of Russian Federation; Federal State Budgetary Institution “Almazov National Medical Research Centre” of the Ministry of Health of the Russian FederationRussian Federation202120072021048495Copyright © Орешко Л.С., Бакулин И.Г., Авалуева Е.Б., Семенова Е.А., Ситкин С.И., 20212021Орешко Л.С., Бакулин И.Г., Авалуева Е.Б., Семенова Е.А., Ситкин С.И.Oreshko L.S., Bakulin I.G., Avalueva E.B., Semenova E.A., Sitkin S.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.nogr.org/jour/article/view/1633

В статье представлены современные представления о целиакии в рамках классификационной концепции глютенассоциированных состояний. Рассмотрены вопросы распространенности заболевания, представлена современная модель этиопатогенеза целиакии, обсуждены клинические проявления и возможности дифференциальной диагностики. Согласно Европейским рекомендациям представлена стратегия мониторинга больных целиакией на амбулаторном этапе, основанная на исходных характеристиках заболевания, регулярности взаимодействия врача с пациентом и профилактике глютен- ассоциированных состояний.

The article presents a modern view of celiac disease within the framework of the classification concept of gluten- associated disorders. The prevalence of the disease, the modern model of the etiopathogenesis of celiac disease, clinical manifestations, and the possibilities of differential diagnosis are discussed. According to the European guidelines, a strategy for monitoring outpatients with celiac disease is presented, based on baseline characteristics of the disease, regular doctor- patient interaction, and prevention of gluten- associated disorders.

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The authors declare that there are no conflicts of interest present.