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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-187-3-186-193</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-1616</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Ранний артрит и заболевания органов пищеварения. Взгляд ревматолога</article-title><trans-title-group xml:lang="en"><trans-title>Early arthritis and digestive diseases. A rheumatologist’s view</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галушко</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Galushko</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">egalushko@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гордеев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gordeev</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лила</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Lila</surname><given-names>A. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное научное учреждение «Научно-исследовательский Институт ревматологии имени В. А. Насоновой» (ФГБНУ НИИР им. В. А. Насоновой)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V. A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное научное учреждение «Научно-исследовательский Институт ревматологии имени В. А. Насоновой» (ФГБНУ НИИР им. В. А. Насоновой); ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» (РМАНПО) Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V. A. Nasonova Research Institute of Rheumatology; Department of Rheumatology, Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>22</day><month>05</month><year>2021</year></pub-date><volume>0</volume><issue>3</issue><fpage>186</fpage><lpage>193</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Галушко Е.А., Гордеев А.В., Лила А.М., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Галушко Е.А., Гордеев А.В., Лила А.М.</copyright-holder><copyright-holder xml:lang="en">Galushko E.A., Gordeev A.V., Lila A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/1616">https://www.nogr.org/jour/article/view/1616</self-uri><abstract><p>Периферический артрит относится к числу самых частых проявлений суставного синдрома, не всегда связанного с ревматическими заболеваниями. Определение его нозологической принадлежности и рациональная терапия на ранней стадии (ранний артрит) представляют сложную клиническую и диагностическую проблему, требующей междисциплинарного подхода. В обзоре представлены вопросы дифференциальной диагностики раннего артрита при таких заболеваниях желудочно-кишечного тракта как воспалительные заболевания кишечника, целиакия, синдром РРР (Панкреатит Паникулит и Полиартрит), Pancreatitis, panniculitis and polyarthritis (PPP-) syndrome) и др., проявляющиеся сходной клинической симптоматикой с такими ревматическими заболеваниями как ранний ревматоидный артрит и спондилоартриты. Большинство представленных в обзоре иммунновоспалительных заболеваний мультисистемны и гетерогенны по клинической симптоматике, течению и исходам. Поэтому диагностический процесс, особенно при раннем артрите с типичным многосистемным вовлечением, носит комплексный познавательный характер и требует синтеза многих данных, обычно не учитываемых в простом алгоритме, основой которого является набор классификационных критериев.</p></abstract><trans-abstract xml:lang="en"><p>Peripheral arthritis is one of the most common manifestations of articular syndrome, not always associated with rheumatic diseases. Determination of its nosological affiliation and rational therapy at an early stage (early arthritis) present a complex clinical and diagnostic problem requiring an interdisciplinary approach. The review presents the differential diagnosis of early arthritis in diseases of the gastrointestinal tract such as inflammatory bowel disease, celiac disease, PPP syndrome (Pancreatitis, panniculitis and polyarthritis (PPP-) syndrome), etc., manifested by similar clinical symptoms with rheumatic diseases such as early rheumatoid arthritis and spondylitis. Most of the immuno-inflammatory diseases presented in the review are multisystemic and heterogeneous in clinical symptoms, course and outcomes. Therefore, the diagnostic process, especially in case of early arthritis with typical multisystem involvement, is comprehensive and cognitive in nature and requires the synthesis of many data that are usually not taken into account in a simple algorithm based on a set of classification criteria.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ранний артрит</kwd><kwd>внекишечные проявления</kwd><kwd>дифференциальный диагноз</kwd><kwd>целиакия</kwd><kwd>воспалительные заболевания кишечника</kwd><kwd>ревматоидный артрит</kwd><kwd>спондилоартрит</kwd></kwd-group><kwd-group xml:lang="en"><kwd>early arthritis</kwd><kwd>extraintestinal manifestations</kwd><kwd>differential diagnosis</kwd><kwd>celiac disease</kwd><kwd>inflammatory bowel disease</kwd><kwd>rheumatoid arthritis</kwd><kwd>spondylitis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Nasonov EL. 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