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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-184-12-16-22</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-1490</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>COVID-19</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>COVID-19</subject></subj-group></article-categories><title-group><article-title>Особенности поражения кишечника при COVID-19</article-title><trans-title-group xml:lang="en"><trans-title>Features of intestinal damage in COVID-19</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сарсенбаева</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Sarsenbaeva</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сарсенбаева Айман Силкановна, кафедра терапии ИДПО, профессор, доктор математических наук</p><p>454092, Уральский федеральный округ, Челябинская область, г. Челябинск, ул. Воровского, 64</p></bio><bio xml:lang="en"><p>Aiman S. Sarsenbaeva, Department of Therapy ICPE, Professor, Doctor of Medical Sciences</p><p>454092, Chelyabinsk, Vorovskogo, 64</p><p>Scopus Author ID: 8580282400</p></bio><email xlink:type="simple">aiman-ss@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8736-5851</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лазебник</surname><given-names>Л. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Lazebnik</surname><given-names>L. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лазебник Леонид Борисович, кафедра Поликлинической терапии, профессор, доктор математических наук</p><p>ул. Делегатская, 20\1, г. Москва, 127473 </p></bio><bio xml:lang="en"><p>Leonid B. Lazebnik, Department of Polyclinic therapy, Professor, doctor of medical Sciences</p><p>Delegatskay str., 20\1, Moscow, 127473</p><p>Scopus Author ID: 7005446863</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО ЮУГМУ Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Higher Education “South-Ural State Medical University” of the Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Московский государственный медико-стоматологический университет им. АИ Евдокимова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Higher Education “A. I. Yevdokimov Moscow State University of Medicine and Dentistry” of the Ministry of Healthcare of the Russion Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>21</day><month>12</month><year>2020</year></pub-date><volume>0</volume><issue>12</issue><fpage>16</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сарсенбаева А.С., Лазебник Л.Б., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Сарсенбаева А.С., Лазебник Л.Б.</copyright-holder><copyright-holder xml:lang="en">Sarsenbaeva A.S., Lazebnik L.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/1490">https://www.nogr.org/jour/article/view/1490</self-uri><abstract><p>Настоящий обзор представляет систематизацию литературного материала о характере вовлечении кишечника в патологический процесс при COVID-19; обсуждается роль феномена «ось кишечник-легкие» в реализации инфекционного процесса, приводится алгоритм выбора безопасной лекарственной терапии у пациентов с воспалительными заболеваниями кишечника, анализ факторов риска антибиотик-ассоциированной диареи.</p></abstract><trans-abstract xml:lang="en"><p>This review presents a systematization of the literature on the nature of intestinal involvement in the pathological process in COVID-19; discusses the role of the “gut-lung axis” phenomenon in the implementation of the infectious process, provides an algorithm for choosing safe drug therapy in patients with inflammatory bowel diseases, and analyzes risk factors for antibiotic-associated diarrhea.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ось кишечник-легкие</kwd><kwd>воспалительные заболевания кишечника</kwd><kwd>COVID-19</kwd><kwd>антибиотик-ассоциированная диарея</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gut-lung axis</kwd><kwd>inflammatory bowel diseases</kwd><kwd>COVID-19</kwd><kwd>antibiotic-associated diarrhea</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Pan A, Liu L, Wang C, et al. 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