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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-183-11-102-112</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-1482</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Фекальная трансплантация: клинические реалии и перспективы в терапии метаболического синдрома</article-title><trans-title-group xml:lang="en"><trans-title>Fecal transplantation: clinical realities and prospects in the treatment of metabolic syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8445-8363</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сас</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Sas</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сас Евгений Иванович, д. м. н., профессор 2 кафедры (терапии усовершенствования врачей)</p><p>194044, Санкт-Петербург, улица Академика Лебедева, д. 6</p></bio><bio xml:lang="en"><p>Evgeny I. Sas, M.D., D. Sc. (Medicine), Professor of 2nd Therapy department of postgraduate education</p><p>194044, St. Petersburg, Akademika Lebedev street, 6</p></bio><email xlink:type="simple">doctorsas@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1095-8787</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гриневич</surname><given-names>В. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Grinevich</surname><given-names>V. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гриневич Владимир Борисович, заведующий 2 кафедрой (терапии усовершенствования врачей), д. м. н., профессор</p><p>194044, Санкт-Петербург, улица Академика Лебедева, д. 6</p></bio><bio xml:lang="en"><p>Vladimir B. Grinevich, Head of 2nd Therapy department of postgraduate education, DSci, professor; Scopus Author ID: 7005167197</p><p>194044, St. Petersburg, Akademika Lebedev street, 6</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барнакова</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Barnakova</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Барнакова Васалина Анатольевна, к. м. н., доцент 2 кафедры (терапии усовершенствования врачей)</p><p>194044, Санкт-Петербург, улица Академика Лебедева, д. 6</p></bio><bio xml:lang="en"><p>Vasalina A. Barnakova, PhD, associate professor of 2nd Therapy department of postgraduate education</p><p>194044, St. Petersburg, Akademika Lebedev street, 6</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБВОУ ВО «Военно-медицинская академия имени С. М. Кирова» МО РФ<country>Россия</country></aff><aff xml:lang="en">Military Medical Academy named after S. M. Kirov<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>14</day><month>11</month><year>2020</year></pub-date><volume>183</volume><issue>11</issue><fpage>102</fpage><lpage>112</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сас Е.И., Гриневич В.Б., Барнакова В.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Сас Е.И., Гриневич В.Б., Барнакова В.А.</copyright-holder><copyright-holder xml:lang="en">Sas E.I., Grinevich V.B., Barnakova V.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/1482">https://www.nogr.org/jour/article/view/1482</self-uri><abstract><p>В обзоре приведен анализ имеющихся данных по клинической эффективности фекальной трансплантации при различных заболеваниях. Определены перспективные направления данного вида терапии, а также нерешенные вопросы, касающиеся как собственно методики, так и оценки эффективности.</p></abstract><trans-abstract xml:lang="en"><p>The review provides an analysis of the available data on the clinical eﬃcacy of fecal transplantation in various diseases. Promising areas of this type of therapy are identiﬁed, as well as unresolved issues regarding both the methodology itself and the evaluation of eﬀectiveness.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>фекальная трансплантация</kwd><kwd>микробиота</kwd><kwd>Clostridium diﬃcile инфекция</kwd><kwd>аутизм</kwd></kwd-group><kwd-group xml:lang="en"><kwd>fecal transplantation</kwd><kwd>microbiota</kwd><kwd>Clostridium diﬃcile infection</kwd><kwd>autism</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Whitman WB, Coleman DC, Wiebe WJ. 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