nogrЭкспериментальная и клиническая гастроэнтерологияExperimental and Clinical Gastroenterology1682-8658«Global Media Technologies»10.31146/1682-8658-ecg-183-11-74-79nogr-1480Research ArticleОБЗОРREVIEWМетаболический синдром и беременность. Есть ли гастроэнтерологический след?Metabolic syndrome and pregnancy. Is there a gastroenterological trace?https://orcid.org/0000-0002-2785-6699ИванюкЕ. С.IvanyukE. S.

Иванюк Елена Сергеевна, к. м. н., преподаватель 2 кафедры (терапии усовершенствования врачей)

194044, Санкт-Петербург, улица Академика Лебедева, дом 6

Elena S. Ivanyuk, assistant Professor

194044, St. Petersburg, Akademika Lebedev street, 6

gastroperm@gmail.comhttps://orcid.org/0000-0003-4839-9578СаликоваС. П.SalikovaS. P.

Саликова Светлана Петровна, д. м. н., доцент, доцент 2 кафедры (терапии усовершенствования врачей)

194044, Санкт-Петербург, улица Академика Лебедева, дом 6

Svetlana P. Salikova, doctor of medical Sciences, associate Professor 2 chair (therapy postgraduate doctors)

194044, St. Petersburg, Akademika Lebedev street, 6

ИванюкГ. Ю.IvanyukG. Y.

Иванюк Галина Юрьевна, заведующая женской консультацией Пермского краевого перинатального центра, врачакушер-гинеколог высшей квалификационной категории

614990, г. Пермь, ул. Пушкина, д. 85

Galina Yu. Ivanyuk, head of the women’s consultation of the Perm regional perinatal center, obstetrician-gynecologist of the highest qualification category

614990, Perm, Pushkin street, 85

ФГБВОУ ВО «Военно-медицинская академия им. С. М. Кирова» МО РФРоссияMilitary Medical Academy named after S. M. KirovRussian FederationГосударственное бюджетное учреждение здравоохранения Пермского края «Ордена «Знак Почёта» Пермская краевая клиническая больницаРоссияState budgetary healthcare institution of the Perm region “Order of the Badge of Honor” Perm regional clinical hospitalRussian Federation202014112020183117479Copyright © Иванюк Е.С., Саликова С.П., Иванюк Г.Ю., 20202020Иванюк Е.С., Саликова С.П., Иванюк Г.Ю.Ivanyuk E.S., Salikova S.P., Ivanyuk G.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.nogr.org/jour/article/view/1480

В последние годы в патогенезе метаболического синдрома (МС) большое значение придается неалкогольной жировой болезни печени (НАЖБП) и нарушению микробно-тканевого комплекса кишечника. В настоящем обзоре обобщены современные данные о возможных патофизиологических механизмах, связывающих НАЖБП, нарушение микробно-тканевого комплекса кишечника и беременность. Анализируются клинические последствия влияния НАЖБП на беременность, развитие акушерских осложнений и неблагоприятных перинатальных исходов.

In recent years, in the pathogenesis of metabolic syndrome (MS), great importance has been attached to non-alcoholic fatty liver disease (NAFLD) and violation of the intestinal microbial-tissue complex. This review summarizes current data on possible pathophysiological mechanisms that link NAFLD, pregnancy, and intestinal microbiota disorders. The clinical consequences of NAFLD influence on pregnancy and development of obstetric complications and adverse perinatal outcomes are analyzed.

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The authors declare that there are no conflicts of interest present.