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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">.31146/1682-8658-ecg-180-8-4-9</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-1419</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПЕРЕДОВАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LEADING ARTICLE</subject></subj-group></article-categories><title-group><article-title>COVID-19 и поражение внутренних органов: что мы знаем, выходя на плато?</article-title><trans-title-group xml:lang="en"><trans-title>COVID-19 and organs damage: what do we know, coming to the ﬂ attening of the curve?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хлынова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Khlynova</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хлынова Ольга Витальевна - заведующая кафедрой госпитальной терапии и кардиологии, член-корр. РАН, доктор медицинских наук, профессор.</p><p>Пермский край, Пермь, ул. Петропавловская, 26, 614000</p></bio><bio xml:lang="en"><p>Olga V. Khlynova - Head of the Department of Hospital Therapy and Cardiology PSMU, Corresponding Member of the Russian Academy of Sciences, Ph.D., Professor.</p><p>614000, Perm, st. Petropavlovskaya, 26</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карпунина</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Karpunina</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Карпунина Наталья Сергеевна - профессор кафедры госпитальной терапии и кардиологии.</p><p>Пермский край, Пермь, ул. Петропавловская, 26, 614000</p></bio><bio xml:lang="en"><p>Nataliya S. Karpunina - Department of Hospital Therapy and Cardiology, PSMU, PhD, Professor.</p><p>614000, Perm, st. Petropavlovskaya, 26</p></bio><email xlink:type="simple">karpuninapsma@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Василец</surname><given-names>Л. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilets</surname><given-names>L. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Василец Любовь Михайловна - профессор кафедры госпитальной терапии и кардиологии.</p><p>Пермский край, Пермь, ул. Петропавловская, 26, 614000</p></bio><bio xml:lang="en"><p>Lubov M. Vasilets - Department of Hospital Therapy and Cardiology, PSMU, PhD, Professor.</p><p>614000, Perm, st. Petropavlovskaya, 26</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение «Пермский государственный медицинский университет имени академика Е. А. Вагнера» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Perm State Medical University named after Academician E. A. Wagner PSMU</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>17</day><month>10</month><year>2020</year></pub-date><volume>0</volume><issue>8</issue><fpage>4</fpage><lpage>9</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Хлынова О.В., Карпунина Н.В., Василец Л.М., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Хлынова О.В., Карпунина Н.В., Василец Л.М.</copyright-holder><copyright-holder xml:lang="en">Khlynova O.V., Karpunina N.S., Vasilets L.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/1419">https://www.nogr.org/jour/article/view/1419</self-uri><abstract><p>Цель представления настоящего обзора заключается в изложении современных данных о поражении сердечно-сосудистой системы и желудочно-кишечного тракта при новой коронавирусной инфекции (COVID-19). Обзор посвящен обобщению мировых данных, известных к июню 2020 года. Предпринята попытка дать патофизиологическое обоснование структурным и функциональным изменениям внутренних органов. Основное внимание в статье уделено поражению сердечно-сосудистой системы, печени и тонкой кишки, а также вопросам диагностики и рационализации базисной терапии воспалительных заболеваний кишечника, артериальной гипертензии и ишемической болезни сердца.</p></abstract><trans-abstract xml:lang="en"><p>The aim of this review is to summarize the world data about cardiovascular and digestive systems damage, caused by COVID-19 infection, known by June 2020. An attempt was made to suggest a pathophysiological explanation of structural and functional changes in internal organs. The main focus of the article is on the damage of the cardiovascular system, liver and small intestine, as well as on the diagnosing and optimizing the basic therapy for inﬂammatory bowel diseases, arterial hypertension and coronary heart disease.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>поражение печени</kwd><kwd>тонкой кишки</kwd><kwd>сердца и сосудов</kwd><kwd>оптимизация лечения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>liver and small intestine damage</kwd><kwd>cardiovascular disorders</kwd><kwd>treatment strategies</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Шляхто Е. В., Конради А. О. Виллевальде С. В. и др. Руководство по диагностике и лечению болезней системы кровообращения (БСК) в контексте пандемии COVID-19. 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