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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-179-7-131-136</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-1406</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭКСПЕРИМЕНТАЛЬНАЯ ГАСТРОЭНТЕРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERIMENTAL GASTROENTEROLOGY</subject></subj-group></article-categories><title-group><article-title>Влияние жиров и их продуктов гидролиза на протеолитическую активность поджелудочного и желудочного соков</article-title><trans-title-group xml:lang="en"><trans-title>The effect of fats and their hydrolysis products on the proteolytic activity of pancreatic and gastric juices</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джалалова</surname><given-names>О. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzhalalova</surname><given-names>O. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Джалалова Озода Козимжановна - соискатель докторант.Андижан, 170127.</p></bio><bio xml:lang="en"><p>Ozoda K. Dzhalalova - doctoral candidate.Andijan, 170127.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алейник</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Aleinik</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алейник Владимир Алексеевич - доктор медицинских наук, профессор, профессор кафедры нормальной физиологии.Андижан, 170127.</p></bio><bio xml:lang="en"><p>Vladimir A. Aleinik - MD, professor, professor of the Department of Normal Physiology.Andijan, 170127.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8338-1122</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жураева</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhuraeva</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жураева Мохигуль Азимжановна - кандидат медицинских наук, доцент, доцент кафедры ВОП-1 лечебный факультет.Андижан, 170127.</p></bio><bio xml:lang="en"><p>Mohigul A. Juraeva - candidate of medical sciences, associate professor, associate professor of the Department of GP-1, Faculty of Medicine.Andijan, 170127.</p></bio><email xlink:type="simple">mohigul_azimovna@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бабич</surname><given-names>С. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Babich</surname><given-names>S. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бабич Светлана Михайловна - кандидат медицинских наук, доцент, заведующая кафедрой социальной гигиены и управления здравоохранением.Андижан, 170127.</p></bio><bio xml:lang="en"><p>Svetlana M. Babich - Candidate of Medical Sciences, Associate Professor, Head of the Department of Social Hygiene and Health Management.Andijan, 170127.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хамракулов</surname><given-names>Ш. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Khamrakulov</surname><given-names>Sh. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хамракулов Шариф Хошимович - доктор медицинских наук, профессор, заведующий кафедрой патологической физиологии.Андижан, 170127.</p></bio><bio xml:lang="en"><p>Sharif K. Khamrakulov - MD, professor, head of the department of pathological physiology.Andijan, 170127.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Андижанский государственный медицинский институт</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Andijan State Medical Institute</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>27</day><month>09</month><year>2020</year></pub-date><volume>0</volume><issue>7</issue><fpage>131</fpage><lpage>136</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Джалалова О.К., Алейник В.А., Жураева М.А., Бабич С.М., Хамракулов Ш.Х., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Джалалова О.К., Алейник В.А., Жураева М.А., Бабич С.М., Хамракулов Ш.Х.</copyright-holder><copyright-holder xml:lang="en">Dzhalalova O.K., Aleinik V.A., Zhuraeva M.A., Babich S.M., Khamrakulov S.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/1406">https://www.nogr.org/jour/article/view/1406</self-uri><abstract><p>Исследовалось влияние различной концентрации продуктов гидролиза жиров на ОПА поджелудочного и желудочного соков с использованием казеиново-жировой эмульсии (казеин + трибутирин, казеин + подсолнечное масло). Сделаны выводы, что продукты гидролиза подсолнечного масла, способствует достоверному снижению ОПА поджелудочного сока, которые менее выражены под влиянием продуктов гидролиза трибутирина. Продукты гидролиза, как подсолнечного масла, так и трибутирина менее выражены в кислой среде на снижение ОПА желудочного сока. Повышение концентрации, как подсолнечного масла, а также трибутирина в составе эмульсии с казеином способствует достоверному повышению ОПА поджелудочного сока. В тоже время эффект трибутирина менее выражен, чем при использовании подсолнечного масла. При этом повышение концентрации как трибутирина, так и подсолнечного масла в меньшей мере влияет на увеличение ОПА желудочного сока.</p></abstract><trans-abstract xml:lang="en"><p>The effect of various concentrations of fat hydrolysis products on the pancreatic and gastric juices OPA using casein-fat emulsion (casein + tributyrin, casein + sunflower oil) was studied. It is concluded that the hydrolysis products of sunflower oil, contributes to a significant decrease in pancreatic juice OPA, which are less pronounced under the influence of tributyrin hydrolysis products.The hydrolysis products of both sunflower oil and tributyrinare less pronounced in an acidic environment to reduce the gastric juice OPA. An increase in the concentration of both sunflower oil and tributyrin in the emulsion with casein contributes to a significant increase in pancreatic juice OPA. At the same time, the effect of tributyrinis less pronounced than when using sunflower oil. At the same time, an increase in the concentration of both tributyrin and sunflower oil to a lesser extent affects the increase in the gastric juice gastric arteries.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>поджелудочный сок</kwd><kwd>желудочный сок</kwd><kwd>протеолитическая активность</kwd><kwd>казеиново-жировая эмульсия</kwd><kwd>продукты гидролиза жиров</kwd><kwd>казеин</kwd><kwd>трибутирин</kwd><kwd>подсолнечное масло</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pancreatic juice</kwd><kwd>gastric juice</kwd><kwd>proteolytic activity</kwd><kwd>casein-fat emulsion</kwd><kwd>fat hydrolysis products</kwd><kwd>casein</kwd><kwd>tributyrin</kwd><kwd>sunflower oil</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Андреева Ю. В. 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