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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-179-7-92-95</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-1401</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ ГАСТРОЭНТЕРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL GASTROENTEROLOGY</subject></subj-group></article-categories><title-group><article-title>Лечение гастроэзофагеальной рефлюксной болезни с синдромом вегетативной дистонии комбинацией ингибитора протонной помпы рабепразола и нейролептика сульпирида</article-title><trans-title-group xml:lang="en"><trans-title>Treatment of gastroesophageal reflux disease with autonomic dystonia syndrome with combination of proton pump inhibitor Rabeprazole and neuroleptic sulpiride</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хамрабаева</surname><given-names>Ф. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Khamrabaeva</surname><given-names>F. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хамрабаева Феруза Ибрагимовна - доктор медицинских наук, профессор, заведующая кафедрой гастроэнтерологии и физиотерапии, декан терапевтического факультета.Ташкент, ул. Паркентская, 51, 10007.</p></bio><bio xml:lang="en"><p>Feruza I. Khamrabaeva - Doctor of Medical Sciences, professor, head of the Department of Gastroenterology and Physiotherapy, Dean of the Faculty of Medicine.10007, Tashkent, st. Parkentskaya 51.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ташкентский институт усовершенствования врачей</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>Tashkent Institute of Postgraduate Medical Education</institution><country>Uzbekistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>27</day><month>09</month><year>2020</year></pub-date><volume>0</volume><issue>7</issue><fpage>92</fpage><lpage>95</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Хамрабаева Ф.И., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Хамрабаева Ф.И.</copyright-holder><copyright-holder xml:lang="en">Khamrabaeva F.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/1401">https://www.nogr.org/jour/article/view/1401</self-uri><abstract><p>По результатам исследования в основной группе пациентов, которые получали комплексное лечение (ИПП и нейролептик), наблюдалась существенная положительная динамика основных клинических проявлений, по сравнению с группой контроля. Все пациенты отмечали значительное уменьшение интенсивности изжоги и болевого синдрома. Применение в комплексном лечение больных ГЭРБ с СВД сульпирида с вегетокорректирующим действием позволило более эффективно купировать болезненные проявления (возможно за счет коррекции вегетативного дисбаланса и как следствие этого снижения выраженности болей) и снизить степень эмоционального переживания телесного дискомфорта, улучшить эмоциональное состояние и психическое здоровье пациентов, а также, повысить уровень их КЖ.</p></abstract><trans-abstract xml:lang="en"><p>According to the results of the study in the main group of patients who received complex treatment (IPP and neuroleptic), there was a significant positive dynamics of the main clinical manifestations, compared with the control group. All patients reported a significant decrease in the intensity of heartburn and pain.The use of probulin with vegetative-corrective action in the complex treatment of patients with GERD with vegetative dystonia syndrome allowed to more effectively stop the painful manifestations and reduce the emotional experience of bodily discomfort, improve the emotional state and mental health of patients, as well as improve their quality of life.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гастроэзофагеальная рефлюксная болезнь</kwd><kwd>синдром вегетативной дистонии</kwd><kwd>ингибитор протонного насоса</kwd><kwd>нейролептик</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gastroesophageal reflux disease</kwd><kwd>vegetative dystonia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Веселова Е. Н. 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